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Erny Tandanu
Medical Education Study Program, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia
Health Professions Medicine & Pharmacology Nursing Public Health

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Description of Serum Urea and Creatinine Levels Pre Hemodialysis and Post Hemodialysis at Royal Prima Hospital in Chronic Kidney Disease Raymond Nazimuddin Putra; Valentine Athania Br Perangin-angin; Sahna Ferdinand; Erny Tandanu
Archives of The Medicine and Case Reports Vol. 2 No. 2 (2021): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v2i2.19

Abstract

Chronic kidney failure describes as the gradual loss of kidney function and it is irreversible, to replace the loss of kidney function a therapy for kidney function is needed, which is hemodialysis. The objective of this research is to know the levels of urea and creatinine serum for pre hemodialysis and post hemodialysis at Royal Prima General Hospital Medan. The methods that are being used for this research are descriptive with 54 patients as samples. The results of this research loss of urea and creatinine serum levels, with the average urea level for pre hemodialysis being 128.11 mg/dL, and the average urea level for post hemodialysis is 43.26 mg/dL with 1,8% of patient with low urea level, 50% with normal urea level, and 48.2% with high urea level. The average creatine level for pre hemodialysis is 11.56 mg/dL, and the average creatine level is 4.3 mg/dL, with all of the patients still having a high creatinine level. The conclusion is there is a drop in both urea and creatinine serum levels, but the urea level for half of the patients did not go down to normal, and for the creatinine level there are none of the patients’ creatinine levels that go down to normal.
Acute Toxicity Testing of White Turmeric Extract (Curcuma zedoaria) on Histopathological Imaging of the Lungs Ainge Rasbina Br Saragih; Fiska Maya Wardhani; Erny Tandanu; Rico Alexander
Archives of The Medicine and Case Reports Vol. 2 No. 4 (2021): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v2i4.125

Abstract

White turmeric (Curcuma zedoaria) is a type of plant whose extract contains compounds that can inhibit carcinogenesis. Acute toxicity test was conducted to determine the safe dose and lethal dose (LD) 50 from the use of a drug substance. This research aimed to determine the effect of the acute toxicity test of white turmeric extract on the histopathological imaging of the lungs. This study is an experimental study with a post test only control group design. A total of 30 Wistar rats was divided into six groups. Data analysis was using one-way ANOVA statistical test, while for lung histopathology using ordinal data which were analyzed descriptively. In conclusion, the acute toxicity test of white turmeric extract on Wistar rats was not toxic and there was no death and no toxic symptoms and no necrosis, congestion and inflammation were found on the histopathological picture of the lungs.
Co-Authors Ainge Rasbina Br Saragih Fiska Maya Wardhani Raymond Nazimuddin Putra Rico Alexander Sahna Ferdinand Valentine Athania Br Perangin-angin