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All Journal Archives of The Medicine and Case Reports
Olga Simó-Servat
Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain / Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ICSIII), Madrid, Spain
Health Professions Medicine & Pharmacology Nursing Public Health

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Pathogenesis Aspects of Microvascular Complications in Diabetic Retinopathy: Narrative Literature Review Olga Simó-Servat; Cristina Hernández; Rafael Simó
Archives of The Medicine and Case Reports Vol. 3 No. 2 (2022): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v3i2.197

Abstract

Chronic hyperglycemic conditions in diabetes mellitus can cause changes that result in chronic complications, both macrovascular and microvascular. There are several mechanisms thought to cause microvascular damage and retinopathy in diabetes, namely the polyol pathway, formation of advanced glycation end products (AGE), activation of protein kinase C (PKC), oxidative stress, and increased activity of the hexosamine pathway.
Co-Authors Cristina Hernández Rafael Simó