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All Journal Indonesian Journal of Cardiology
Vidya Gilang Rejeki
Departemen Kardiologi dan Vaskular Universitas Indonesia / RSJPD Harapan Kita
Health Professions Medicine & Pharmacology

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Aktivasi Neurohormonal dan Remodeling Atrium Kiri pada Stenosis Mitral Vidya Gilang Rejeki; Bambang Budi Siswanto; Nani Hersunarti
Jurnal Kardiologi Indonesia Vol. 37, No. 1 Januari - Maret 2016
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v37i1.555

Abstract

Mitral stenosis is closely related with the hemodynamic consequences of obstructed mitral leaflet. Definitive therapy in mitral stenosis is mechanical intervention. Late presentation of mitral stenosis patients to medical facilities due to limited health facilities and Indonesian’s demographic, often make patients’ condition deteriorates, in which intervention need to be delayed or even no longer suitable. Stretched left atrium and reduced cardiac output stimulate several neurohormonal activation; renin-angiotensin-aldosterone and symphatetic nervous system. Left atrial remodeling further worsen hemodynamic ststus. Renin-angiotensin-aldosterone and sympathetic blockage could improve mitral stenosis patients’ condition with close observation to hypotension status.
Co-Authors Bambang Budi Siswanto Nani Hersunarti