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All Journal Nurse Media Journal of Nursing MNJ (Malang Neurology Journal) The Indonesian Biomedical Journal Majalah Kesehatan FKUB Indonesian Journal of Cardiology ACI (Acta Cardiologia Indonesiana) Manuju : Malahayati Nursing Journal Jurnal Respirologi Indonesia Heart Science Journal MAHESA : Malahayati Health Student Journal Narra J Cermin Dunia Kedokteran Indonesian Nursing Journal of Education and Clinic (Jurnal Pendidikan dan Praktik Keperawatan Indonesia) Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute
Bambang Budi Siswanto
Department Of Cardiology And Vascular Medicine, Faculty Of Medicine, University Of Indonesia, And National Cardiovascular Center Harapan Kita, Jakarta
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Comparison of Roles between Alcohol Ablation and Surgical Myectomy in Hypertrophic Cardiomyopathy Kusuma, Nico; Pranata, Raymond; Vania, Rachel; Siswanto, Bambang Budi
Indonesian Journal of Cardiology Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i2.733

Abstract

Hypertrophic cardiomyopathy is a genetic myocardial disease that may extend to leftventricular outflow tract obstruction. Alcohol septal ablation (ASA) is preferred for itsnon-surgical, agreed as the safest way for advanced aged, or those with high risk for surgicalprocedure or comorbidities. On the other hand, surgical myectomy (SM) remainsas gold standard, established to be the most consistent to achieve optimal hemodynamicand spare longevity, regardless selective use. This article reviews the advantages anddisadvantages between SM and ASA ablation from its outcome, mortality, pre- and postprocedural,and patient’s profile selection.
Exercise training in heart failure: role, prescription and program Pranata, Raymond; Yonas, Emir; Siswanto, Bambang B.; Purwowiyoto, Budhi S.
Indonesian Journal of Cardiology Vol 38 No 4 (2017): October - December 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i4.788

Abstract

Heart failure is one of the most common cardiovascular diseases and is a final pathway of various cardiac pathologies. Exercise intolerance and dyspnea accompanied by dete­riorating quality of life are common issues in those suffering from heart failure and may persist despite optimal medical therapy. Exercise training in heart failure theoretically helps to slow down the deterioration of the heart by antagonizing excess neurohormonal activity in heart failure, which translated into better functional capacity and quality of life. Exercise prescription is a mean of assessing and interpreting clinical information and applying the principles of training to develop an appropriate regimen and should be tailored to patient’s clinical condition. Resistance training improves peak VO2, exercise capacity and quality of life in heart failure patients. Both continuous and interval exercise training are linked to better quality of life despite ambiguous results in mortality. The aim of this article is to discuss the benefits of exercise in patients with congestive heart failure, exercise prescription, and exercise program including high-intensity interval training, continuous training and resistance exercise.   Abstrak Gagal jantung adalah salah satu penyakit kardiovaskular yang paling sering ditemui dan merupakan akhir daripada banyak jenis patologi jantung. Intoleransi olahraga dan sesak nafas disertai dengan memburuknya kualitas hidup merupakan beberapa masalah yang sering dihadapi oleh pasien gagal jantung, meskipun telah diberikan pengobatan yang optimal. Latihan olahraga pada gagal jantung secara teoritis dapat memperlambat menurunnya fungsi jantung dengan melawan aktivitas neurohormonal yang meningkat pada kondisi gagal jantung yang dicerminkan dengan kapasitas fungsional dan kualitas hidup yang lebih baik. Preskripsi olahraga meliputi pemeriksaan dan interpretasi dari informasi klinis dan aplikasi dari prinsip latihan untuk membentuk regimen yang sesuai dan harus di sesuaikan dengan keadaan klinis pasien. Latihan beban memperbaiki fungsi VO2 puncak, kapasitas olahraga dan kualitas hidup pada pasien dengan gagal jantung. Kedua metode olahraga baik secara kontinu ataupun interval dihubungkan dengan kualitas hidup yang lebih baik meskipun masih ambigu dalam hal mortalitas. Tujuan artikel ini adalah membahas manfaat latihan fisik pada pasien dengan gagal jantung kongestif, cara peresepan serta membahas program high intensity interval training, continuous training serta latihan beban.
Role of Highly Sensitive Cardiac Troponin T Assay in Stable Coronary Artery Disease Pranata, Raymond; Kusuma, Nico; Vania, Rachel; Siswanto, Bambang Budi
Indonesian Journal of Cardiology Vol 39 No 1 (2018): January - March 2018
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v39i1.794

Abstract

Cardiac troponins (cTn) are the preferred biomarkers of myocardial necrosis, usually used for diagnosis and risk stratification in acute coronary syndromes. Highly sensitive troponin T (hs-cTnT) may be elevated in stable coronary artery disease (SCAD), in which subclinical plaque erosion or rupture and distal embolization and subclinical ischemic episode. hs-cTnT may be used as a prognostic marker in SCAD and can predict cardiovascular events and patient’s mortality rate. In this article, plaque characteristic that is linked to hs-cTnT, it’s used as prognostic biomarker and comparison to other indicators are the focus of discussion.   Abstrak Troponin adalah biomarker yang paling disukai untuk mendeteksi nekrosis miokardium dan untuk mendiagnosis dan stratifikasi risiko pada sindrom koroner akut. Highly sensitive troponin T (hs-cTnT) dapat meningkat pada penyakit jantung koroner stabil dimana terjadi ruptur plak atau erosi dan embolisasi distal sublklinis, dan episode iskemik subklinis. Sehingga biomarker tersebut dapat digunakan sebagai marker prognostik pada penyakit jantung koroner stabil dan dapat memprediksi angka kejadian kardiovaskular dan tingkat mortalitas pasien. Pada artikel ini akan dibahas mengenai karakteristik plak yang dihubungkan dengan peningkatan hs-cTnT, pengunaan sebagai biomarker prognostik dan serta perbandingan dengan indikator lainnya.
ASSOCIATION OF HBA1C AND NEUTROPHIL LYMPHOCYTE RATIO WITH NORMAL-TENSION GLAUCOMA IN METABOLIC SYNDROME AND OBSTRUCTIVE SLEEP APNEA RISK PATIENTS Prayitnaningsih, Seskoati; Asrory, Virna Dwi Oktariana; Nusanti, Synthia; Listyaningsih, Erlin; Siswanto, Bambang Budi; Santoso, Anwar
MNJ (Malang Neurology Journal) Vol. 7 No. 2 (2021): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2021.007.02.14

Abstract

Background: Normal-Tension_Glaucoma (NTG) is an eye disease and characterize with low intraocular pressure (IOP) levels. In population-based settings, the diagnose of glaucoma is based on the IOP levels of 21 mmHg, and its usually delayed. A recent study HbA1c levels could lead to IOP changes. Obstructive Sleep Apnea (OSA) result oxidative stress that results an altered function of neutrophil in patients with NTG. Objective: To_evaluate the association of HbA1c, Netrophil-to-Lymphocyte Ratio_(NLR) toward NTG as its novel early detection.Methods: This study divided into two groups consisted of Metabolic Syndrome ( MS) + OSA without eye disorder as control (15 subjects) and MS + OSA + NTG patients (14 subjects). IDF criteria was used to established MS, and risk of OSA determined by STOP-BANG Questionnaire. The diagnosis of NTG was confirmed by normal IOP measured by Tonopen. Mean Defect (MD) of visual field evaluated by Automated Humphrey Perimetry, Retinal Nerve Fiber Layer (RNFL) established by OCT. HbA1c measured by ELISA and NLR by flowcytometry. Statistical analysis consisted of comparison and correlation testResults: The ratio of CD was significantly higher in NTG patients (0.54 ± 0.13) compared to control (0.26 ± 0.07; p<0.001). MD was also higher in subjects with NTG (6.80 ± 3.90) compared to control (4.97 ± 2.28; p=0.134). Mean RNFL was lower in subjects with NTG (87.95 ± 28.29) compared to control (95.07 ± 26.66; p=0.035). Positive correlation between HbA1C-MD (r = 0.456, p = 0.013) and NLR-RNFL thinning (r = 0.525, p = 0.003) was existed in Metabolic Syndrome (MS) patients.Conclusion: Patients with MS and OSA risk have an increased risk of NTG. A novel association between Hba1C levels, NLR and NTG was also identified.
Pengalaman Awal Tindakan MitraClip di Pusat Jantung Nasional Harapan Kita, Jakarta Almazini, Prima; Hersunarti, Nani; Soerarso, Rarsari; Budi Siswanto, Bambang; Firman, Doni; M Soesanto, Amiliana
Cermin Dunia Kedokteran Vol 43, No 3 (2016): Kardiologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (594.129 KB) | DOI: 10.55175/cdk.v43i3.27

Abstract

Latar Belakang: MitraClip merupakan pilihan terapi untuk pasien regurgitasi katup mitral berat yang berisiko tinggi untuk operasi. Tujuan penelitian ini adalah melaporkan tindakan MitraClip di Pusat Jantung Nasional Harapan Kita Jakarta. Metode: Penelitian retrospektif di Pusat Jantung Nasional Harapan Kita, Jakarta. Data diperoleh dari database komputer dan rekam medis dari Februari 2014 sampai Januari 2015, kemudian dianalisis dengan SPSS. Hasil: Enam orang pasien berusia 51 – 75 tahun, menjalani tindakan MitraClip; 5 pasien regurgitasi katup mitral berat dan 1 pasien regurgitasi katup sedang. Satu pasien perempuan dan 5 pasien laki-laki. Dua pasien merupakan regurgitasi mitral degeneratif dan 4 pasien regurgitasi mitral fungsional. Dua pasien dipasangi satu buah MitraClip dan 4 pasien dipasangi dua buah MitraClip. Setelah tindakan, derajat regurgitasi berkurang menjadi ringan pada 2 pasien dan menjadi sedang pada 4 pasien. Dimensi diastolik akhirventrikel kiri berkurang dari 66 ± 6,5 mm saat awal menjadi 59 ± 7,3 mm (p=0,04) saat pulang. Dimensi sistolik akhir ventrikel kiri berkurang dari 50 ± 10,6 mm saat awal menjadi 48 ± 10,0 mm saat pulang (p=0,27). Satu bulan setelah tindakan MitraClip, 2 pasien dengan kelas fungsional I dan 4 pasien dengan kelas fungsional II. Tidak ada pasien yang meninggal dalam perawatan di rumah sakit. Satu pasien perawatan ulang di rumah sakit karena gagal jantung. Simpulan: MitraClip merupakan pilihan terapi yang efektif dan aman untuk pasien regurgitasi mitral degeneratif dan fungsional yang risiko tinggi untuk operasi. Dimensi ventrikel kiri, kelas fungsional NYHA, derajat keparahan regurgitasi katup, dan tingkat perawatan ulang mengalami perbaikan setelah dipasang MitraClip.
Intoksikasi Digoksin: Bagaimana Cara Mengenali Dan Penatalaksanaannya Dewi H Suprobo; Bambang B Siswanto; Yoga Yuniadi; Ganesja M Harimurti
Jurnal Kardiologi Indonesia Vol. 32, No. 1 Januari - Maret 2011
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v32i1.120

Abstract

Background: Digitalis is the oldest compound in cardiovascular medicine that continues to be used in contemporary clinical practice. It is one of the most frequently prescribed medications and has historically been implicated as one of the most common causes of adverse drug reactions. Despite the fact that digitalis preparations have been used  therapeutically for more than 200 years, diagnosis of digoxin toxicity remains difficult. Signs and symptoms associated with toxicity are nonspecific, as are electrocardiographic changes, and the “therapeutic” and “toxic” concentrations overlap.Objective: to present a case report of digoxin intoxication and to review the diagnosis and management of the disease.Summary: We have reported a case related to intoxication of a drug that is one of the most frequently prescribed medications and has historically been implicated as one of the most common causes of adverse drug reactions. This fact is reasonable since digoxin has a narrow margin of safety, where at the therapeutic dosage digoxin could induce intoxication. Moreover the response to this drug is influenced by many factors. Although the general manifestation of digoxin intoxication is not specified, but in patient who are in digoxin therapy with clinical manifestation of digoxin intoxication, we have to put digoxin intoxication as one of our differential diagnosis. The diagnosis is supported by the ECG manifestation and confirmed by the examination of serum digoxin level. Eventhough, normal digoxin level could also induce intoxication. The initial management of digoxin intoxication is early recog -nition that a dysrhythmia and/or noncardiac manifestation may be related to digitalis intoxication and stop the digoxin therapy. Immunotherapy, in hemodynamically stable or unstable patients, is a first-line therapy.
Korelasi antara kadar plasma NT-proBNP dengan Kecepatan Doppler Jaringan di anulus katup mitral pada penderita Gagal Jantung Raja Adil C Siregar; Harmani Kalim; Bambang Budi Siswanto; Amiliana M Soesanto
Jurnal Kardiologi Indonesia Vol. 31, No. 3 September - Desember 2010
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v31i3.129

Abstract

Background.N-terminal pro brain natriuretic peptide (NT-proBNP) will release from myocite granules in a condition of increased cardiac wall-stress in heart failure (HF) patients, and its plasma level elevation had been widely used as a parameter of diagnosis, functional class, treatment monitoring and prognostication. Pulsed-wave tissue Doppler velocities of mitral annulus (Tissue Doppler Imaging/TDI) currently known had an ability to detect move-ment changes of cardiac wall in HF patients. But only few research to see the correlation between them, with various selection of patients and results.Aim. To determine whether plasma NT-proBNP levels correlate with mitral annulus velocities measured by TDI and to search which component had the strongest correlation.Methods.One hundred consecutive patients with HF who came for echocardiography examination in The National Cardiac Center Harapan Kita Jakarta underwent an additional TDI procedure (Sm, Emand E/Em component). Before or after echocardiography, venous blood sample was collected for plasma NT-proBNP examination. We determined the cor-relation between plasma NT-proBNP level and TDI results, and assessed which component had the strongest correlation.Results.There were 74 men and 26 women of HF patients with mean of age 54 y.o. Functional NYHA Class II were 28 patients, NYHA Class III 42 patients and NYHA Class IV 30 patients. The causes of HF were CAD 49 patients, HHD 19 patients, Valve Disease 23 patients, DCM 8 patients and other 1 patient. There were 64 patients with sinus rhythm and 36 patients with atrial fibrillation. There were 17 diastolic HF patients and 83 systolic HF patients. Fifty patients with significant MR and 50 patients without significant MR. We found the strongest significant negative correlation (r= -0,713, p0,000) between plasma NT-proBNP level and Emcomponent. Smalso had a significant negative correlation, but Emhad a stronger correlation than Sm. E/Emcomponent had a weak significant positive correlation.Conclusion.Elevated plasma NT-proBNP levels correlates strongly with declining velocities of TDI early diastolic Emcomponent in HF patients.
Intervensi penyakit jantung koroner dengan Sindroma Gagal Jantung I Made Putra Swi Antara; Yoga Yuniadi; Bambang Budi Siswanto
Jurnal Kardiologi Indonesia Vol. 30, No. 1 Januari - April 2009
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v30i1.176

Abstract

Revaskularisasi koroner pada pasien dengan gagal jantung seringkali menjadi keputusan yang sulit akibat diperlukannya pertimbangan antara keuntungan dan risiko perioperatif yang lebih besar pada kelompok pasien seperti ini. Sementara itu, angka mortalitas pasca tindakan CABG pada pasien dengan gagal jantung di Pusat Jantung Nasional Harapan Kita (PJNHK) cukup tinggi. Data yg tercatat pada tahun 2006-2008 menunjukkan bahwa 14 dari 85 orang (16,4%) pasien akhirnya meninggal di rumah sakit.Apakah revaskularisasi dengan PCI pada penyakit jantung koroner (PJK) dengan EF rendah namun miokardium yang viabel memiliki peranan di PJNHK? Melaui pemaparan kasus ini akan didiskusikan manajemen Sindroma Gagal Jantung yang disebabkan oleh PJK dengan EF buruk menggunakan revaskularisasi PCI pada pasien yang menolak CABG.
Korelasi Antara Durasi QRS, Fungsi Ventrikel Kanan dan Disinkroni Ventrikel Kiri Pasca Koreksi Tetralogi Fallot Retna Dewayani; Bambang Budi Siswanto; Poppy S Roebiono; Anna Ulfah Rahajoe; Indriwanto Sakidjan; Ganesja M Harimurti
Jurnal Kardiologi Indonesia Vol. 28, No. 4 Juli 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i4.229

Abstract

Background. QRS duration has long been established as a strong predic-tor of sudden cardiac death in patients after surgical correction of Tetral-ogy of Fallot (TOF). Several factors has been correlated to QRS duration, i.e severity of pulmonal regurgitation and right ventricular volume after TOF correction. But there is no established relation between right ven-tricular function and QRS duration after surgical correction TOF.Objectives. We aimed to investigate the relation between QRS duration and right ventricular function and whether patients after TOF repair with right bundle branch block have left ventricular dissynchrony.Methods.50 patients with repaired TOF were studied. Right ventricular function were derived from tissue Doppler imaging Tei index. Left ven-tricular dissynchrony were derived from tissue Doppler imaging. The time interval between the onset of QRS complex and the onset of systolic ejec-tion was measured for six left ventricular basal wall, i.e septal, lateral, anteroseptal, posterior, anterior and inferior wall. Mechanical delay from septal to lateral wall, antero-septal to posterior wall and anterior to infe-rior wall was calculated. Measured data were correlated with QRS dura-tion.Results.There was relation between QRS duration and right ventricular function (P = 0.028, r = 0.44). Ten (20%) of the examined patients after TOF repair had LV dissnynchrony particularly in patients with RBBB and prolonged QRS duration (160 ± 9 ms).Conclusions.There is correlation between right ventricular function and QRS duration. Left ventricular dissynchrony may exist in patients after TOF repair with RBBB.
Natrium Urin Petanda Surrogate Brain Natriuretic Peptide Plasma Pasien Infark Miokard dengan Elevasi ST? Januar W Martha; Hariadi Hariawan; S Taofan; Nani Hersunarti; Bambang B Siswanto
Jurnal Kardiologi Indonesia Vol. 28, No. 1 Januari 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i1.263

Abstract

Background. High level of Brain Natriuretic Peptide (BNP) was suspected as a predictor of adverse events in acute ST Elevation Myocardial Infarc-tion (STEMI). Unfortunately, the cost and availability of BNP assay had hampered its use. Natriuresis is one of the hallmark effect of raised BNP and measuring urinary sodium might offer insight to the plasma BNP. This study aims to search for any correlation between measured plasma BNP and urinary sodium in patients presenting with acute STEMI.Methods. In an observational descriptive analytic study, we selectively in-cluded patients presenting with acute STEMI and checked for plasma BNP and urinary sodium. All patients had no symptoms or therapy of heart failure prior to admission, had no prior MI, had no valvular abnormalities, and had normal renal function. Plasma BNP was tested using immunoassay method from Abbot Diagnostics, while urinary sodium with ionic specific electrode method. Specimen for plasma BNP were taken at the admission while urinary sodium in the next morning, taking account of urine volume. Results. There were 17 patients, 15 were (82.4%) men, with age 55.1+8.2 years old, onset of STEMI 18.6+2.3 hours, and left ventricular ejection fraction (LVEF) 47.6+11.6%. The urinary sodium was 85.1+34.3 mEq/L, and plasma BNP 449.7+48.8 pg/ml. Pearson’s correlation and linear re-gression analysis showed positive correlation between urinary sodium and plasma BNP (r = 0.71). In multivariate analysis, plasma BNP (p<0.01) and LVEF (p<0.05) were the major influencing factors for urinary sodium level.Conclusion.This study revealed a strong correlation between plasma BNP and urinary sodium in patients presenting with acute STEMI. While mea-surement of urinary sodium cannot replace plasma BNP, it might actually reflect plasma BNP level.
Co-Authors Achir Yani S. Hamid Adi, Andi Wahjono Agung Waluyo Ambari, Ade Meidian Amiliana M Soesanto Amiliana M. Soesanto Andi Mahavira Andy Kristyagita Anna Ulfah Rahajoe Anwar Santoso Aria Kekalih Asrory, Virna Dwi Oktariana Astari Pranindya Sari Basuni Radi BRM Ario S. Kuncoro Budhi Antariksa Budhi S. Purwowiyoto Dedi Afandi Desandri, Dwita Rian Dewi H Suprobo Dewi H Suprobo DEWI IRAWATI Dewi Irawati Dewi Irawati Diana Septiyanti Doni Firman Dwiputra, Bambang Emir Yonas Endang Ratnaningsih Erwin Mulia Fatoni, Mukhamad Ganesja M Harimurti Ganesja M Harimurti Gipta Galih Widodo Hadrian Deka Hananto Andriantoro Harahap, Alida R. Harahap, Alida Rosita Hari Utomo Hariadi Hariawan Harmani Kalim Herliana , Rini Huda , Khoirul I Made Putra Swi Antara Idrus Alwi Ikhda Ulya, Ikhda Indarto, Malik Jantra Indriwanto Sakidjan Januar W Martha Jaya, Irvantri Aji Junaiti Sahar Jusup Endang Juzni Alkatiri Katsukawa, Hajime Kusuma, Nico Listyaningsih, Erlin Lukman H. Makmun Muhammad Munawar Nani Hersunarti Nani Hersunarti Nani Hersunarti Nani Hersunarti Nani Hersunarti Nani Hersunarti Nani Hersunarti Nani Hersunarti Nico Kusuma Nico Kusuma Nitia A. Asbarinsyah Nur Haryono Nurhay Abdurachman Nusanti, Synthia Oktarina, Virna Dwi Pius Almindu Leki Berek Poppy S Roebiono Pranata, Raymond Pratama, Erlan Anugrah Prima Almazini Purwowiyoto, Budhi S. Rachel Vania Rachel Vania Radityo Prakoso Raja Adil C Siregar Rarsari S. Soerarso Rarsari Soerarso Rarsari Soerarso Rarsari Soerarso Rarsari Soerarso Rarsari Soerarso Raymond Pranata Retna Dewayani Rif'ati, Lutfah Rizki Rizki Rony Mario Candrasatria, S Taofan Sadikaningtya, Lirasati Sekarsari, Rita Seskoati Prayitnaningsih Siska Sulistiowati Sri Yona Syntia Nusanti Tambunan, Tresia Fransiska Ulianna Tambunan, Tresia FU. Teuku Heriansyah, Teuku Tony Suharsono, Tony Triangto, Kevin Vania, Rachel Vidya Gilang Rejeki Wahju Aniwidyaningsih Wendy M. Saragih Wienta Diarsvitri William Sanjaya Wisnu Jatmiko Yoga Yuniadi Yonas, Emir