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All Journal Indonesian Journal of Cardiology Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Ali Nafiah Nasution
Universitas Sumatera Utara
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Precordial ST Segment Depression on Admission Electrocardiogram as a Simple Noninvasive Tool for Predicting Coronary Artery Disease Complexity in Patients with Inferior Myocardial Infarction Jaya Suganti; Anggia Chairuddin Lubis; Abdullah Afif Siregar; Andika Sitepu; Cut Aryfa Andra; Ali Nafiah Nasution; Harris Hasan
Jurnal Kardiologi Indonesia Vol 40 No 4 (2019): Indonesian Journal of Cardiology: October-December 2019
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v40i4.849

Abstract

Precordial ST Segment Depression on Admission Electrocardiogram as a Simple Noninvasive Tool for Predicting Coronary Artery Disease Complexity in Patients with Inferior Myocardial Infarction Jaya Suganti, Anggia Chairuddin Lubis, Abdullah Afif Siregar, Andika Sitepu, Cut Aryfa Andra, Ali Nafiah Nasution, Harris Hasan Department of Cardiology and Vascular Medicine, Faculty of Medicine University of Sumatera Utara, Haji Adam Malik General Hospital, Medan, Indonesia Background: Whether a precordial ST segment depression (PSTD) is merely a benign electrical phenomena or a sign of multivessel coronary artery disease (MVCAD) in inferior myocardial infarction (MI) remains unclear. The objective of this study is to analyze the complexity of coronary artery disease (CAD) in inferior MI patients with PSTD and to investigate whether PSTD can be used as a predictor of MVCAD in inferior MI. Methods: Patients with inferior MI were divided into two groups based on the presence of PSTD on admission ECG and were compared based on the patient’s coronary artery complexities. Results: A total of 215 patients with inferior MI were found in this study period, with 102 patients meet the inclusion and exclusion criteria. Patients with PSTD had a higher incidence of MVCAD and SYNTAX score. Further analyzes showed PSTD on admission ECG was an independent predictor of MVCAD in inferior MI [45 (66%) vs 23 (34%); OR 4.097; 95% CI 1.638-10.247; p=0.003). Conclusion: In daily clinical practice, PSTD on admission ECG may serve as a simple noninvasive tool for predicting MVCAD or a more complex CAD in inferior MI. Keywords: Precordial ST Segment depression, inferior myocardial infarction, SYNTAX score
Characteristics of Heart Failure Patients with Reduced Left Ventricular Ejection Fraction (HFrEF) Using Angiotensin Receptor-Neprilysin Inhibitors (ARNI) Compared to Angiotensin Converting Enzyme-Inhibitor (ACE-I)/Angiotensin Receptor Blocker (ARB) Therap Grace Nikensari; Cut Aryfa Andra; Ali Nafiah Nasution; Anggia Chairuddin Lubis; Kamal Kharrazi Ilyas
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 8 No. 1 (2026): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v8i1.25086

Abstract

BACKGROUND: Heart failure with reduced ejection fraction (HFrEF) remains a major cause of cardiovascular morbidity. While guideline-directed medical therapy, including Angiotensin Receptor Neprylisin Inhibitor (ARNI) dan Angiotensin Converting Enzyme-Inhibitor (ACE-I)/Angiotensin Receptor Blocker (ARB), is well-established, real-world clinical profiling of these patients in Indonesia remains limited. OBJECTIVES: To evaluate and compare the baseline clinical, demographic, and pharmacological characteristics of HFrEF patients receiving ARNI versus ACE/ARB therapies at Haji Adam Malik Hospital, Medan. METHODS: This cross-sectional, descriptive study was conducted at the integrated heart center polyclinic from August to December 2025. We consecutively enrolled 50 eligible HFrEF outpatients, consisting of 25 patients receiving ACE/ARB and 25 patients receiving ARNI therapies. Data regarding demographics, medical history, and medication records were extracted and analyzed. RESULTS: The cohort had an overall mean age of 57.6 years and was predominantly male (78%). The primary underlying etiology was Ischemic Cardiomyopathy (86%). Key comorbidities included hypertension (54%) and diabetes mellitus (32%). Overall analysis demonstrated that demographic and clinical parameters, including age, systolic blood pressure, and comorbidities, were not significantly different between patients receiving ACE/ARB and those receiving ARNI (all p > 0.05). CONCLUSION: HFrEF patients in our center are predominantly male with an ischemic etiology and a significant burden of cardiometabolic comorbidities. Baseline clinical profiles are highly comparable between those prescribed ARNI and ACE/ARB therapies, providing valuable real-world data for the optimization of HFrEF management.
Co-Authors Abdullah Afif Siregar Andra, Cut Aryfa Grace Nikensari Harris Hasan Jaya Suganti Kamal Kharrazi Ilyas Lubis, Anggia Chairuddin Sitepu, Andika