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All Journal Buletin Farmatera Indonesian Journal of Cardiology Sumatera Medical Journal SCRIPTA SCORE Scientific Medical Journal Heart Science Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) The Journal of Society Medicine (JSOCMED)

Lubis, Anggia Chairuddin

Departemen Kardiologi Dan Kedokteran Vaskular Fakultas Kedokteran Universitas Sumatera Utara/RS Haji Adam Malik Medan

Author-ID : 1249408

Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Corelation Between Sum of Precordial ST Depression in Acute Inferior Myocardial Infarction with Stenosis Severity of Left Anterior Descending Artery Karo, Kartika br; Ketaren, Andre Pasha; Hasan, Refli; Hasan, Harris; Mukhtar, Zulfikri; Lubis, Anggia Chairuddin
Sumatera Medical Journal Vol. 2 No. 1 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Background : There were many studies proved that precordial ST depression in Inferior STEMI show LAD disease from angiografi, but there were also many who unproved . Altought LAD disease was not the main cause of precordial ST depression in Inferior STEMI, but there were many patients with Inferior STEMI who had high grade LAD disease. Sum of precordial ST depression is one of ECG criteria that can help us to prove it . The aim of this study in to know if there is corelation between sum of precordial ST depression with LAD disease and the severity of LAD disease in Inferior STEMI patients with precordial ST depression . Methods : We analized 60 patients inferior STEMI with precordial ST depression onset less than 24 hours that hospitalized in Haji Adam Malik General Hospital since December 2013-June 2017. Patients were divided in to 4 groups based on sum of precordial ST depression. Bivariate analysis were made to see the corelation between sum of precordial ST depression with LAD disease and severity of LAD, p value < 0.05 is statistically significant. Result : Bivariate analysis show that there is strong corelation between sum of precordial ST depression with LAD disease (p=0.01). Sum of precordial ST depression also corelate with severity of LAD (p=0.01). There are also corelation with location of the lesion in proximal LAD and the complexity of the lesion but not statistically significant (p=0.233 and p=0.102). Analysis ROC curve sum of precordial ST depression to LAD disease give the cut off ≥5.15 mm with sensitivity 70% and spesificity 76.2%(AUC 0,752 ,95% CI: 0,620 – 0,883 p<0,001) Conclusion : There is strong corelation between sum of precordial ST depression with high grade LAD disease. The more the sum of precordial ST depression the more posibility high degree LAD disease ( p=0.01).

Perubahan Fungsi Ventrikel Kiri pada Penderita HIV Anggia Chairuddin Lubis; Abdullah Afif Siregar; Sutomo Kasiman
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.72

Background. Patients with HIV have increased risk for myocardial dysfunction but the underlying mechanisms remain unknown.Methods & Results. This study evaluated noninvasively ventricular function in HIV infected patients with no clinical evidence of cardiovascular disease, with determination of left ventricular systolic and diastolic function, as well as measurement of CD 4. Between November 2009 and June 2010, 22 patients agreed to participate in a follow up study. All patients had normal LVEF and FS at both examinations. There was no evidence for a relationship between LVEF changes and either CD 4 changes, CD 4 nadir and HIV stadium. However an increase in mean EPSS was observed at follow up (p=0.045) and associated with lower CD 4 cell counts. At the initial visit, 1 patient had left ventricular dysfunction, and 4 patients at follow up. All patients had normal TAPSE values at both examinations.Conclusion. HIV related cardiomyopathy appears not to constitute a problem in HAART era. However subclinical cardiac abnormalities are frequently observed. The usefulness of systematic noninvasive screening in this population should be considered.

Value of Fragmented QRS Complex on 12-lead ECG as A Valuable Marker of Myocardial Damage of CAD Patients andrico tobing; Anggia Chairuddin Lubis; Edison Bun; Harris Hasan
Jurnal Kardiologi Indonesia Vol 40 No 2 (2019): Indonesian Journal of Cardiology: April-June 2019
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v40i2.736

Background: Presence of Fragmented QRS (fQRS) on a 12-lead Electrocardiogram (ECG) was associated with various cardiac diseases. This phenomenon could represent as an electrical disruption of conduction system following myocardial damage due to coronary artery disease (CAD). We aimed to investigate the value of fQRS to detect the myocardial scar as detected by SPECT Myocardial Perfusion Imaging (MPI). Methods: A cross-sectional study of patients with clinical diagnosis of CAD who underwent Cardiac SPECT. The fQRS defined as morphologies of QRS wave (<120 ms), which included an additional R wave (Râ€™), notching in the nadir of S wave, or >1 Râ€™ (fragmentation) in 2 contiguous leads, corresponding to a major coronary artery territory. Pathological Q wave, paced rhythm, typical right or left bundle branch block pattern with QRS duration of â‰¥ 120 ms were excluded. MPI was interpreted by visual analysis and semi-quantitative scores on 17-segment assessment according to standard nomenclature. Results: Total of 72 patients (49 males, mean age 54.7 Â± 9.8 years). fQRS was found in 46 patients (64%). The frequency of myocardial scar was significantly higher in patients with fQRS (89% vs. 15%, p<0.05). Sensitivity, specificity, positive and negative predictive value of fQRS for any of myocardial scar as detected by SPECT analysis were 91%, 81%, 89%, and 84%, respectively. From regional scar analysis, fQRS has sensitivity and specificity of 87% and 90% for anterior wall, 76% and 80% for inferior wall, 73% and 79% for lateral wall. LVEF was significantly lower in patients with fQRS (36.9Â±2.1 vs. 53.2Â±2.2, p< 0.05). Conclusion: The fragmented QRS could serve as a novel ECG marker to detect and localize the myocardial damage in CAD patients. Regional fQRS patterns denote the presence of regional myocardial scar and are a valuable diagnostic marker of CAD with good sensitivity and specificity. Keywords: fragmented QRS, SPECT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v40i4.849

Precordial ST Segment Depression on Admission Electrocardiogram as a Simple Noninvasive Tool for Predicting Coronary Artery Disease Complexity in Patients with Inferior Myocardial Infarction Jaya Suganti, Anggia Chairuddin Lubis, Abdullah Afif Siregar, Andika Sitepu, Cut Aryfa Andra, Ali Nafiah Nasution, Harris Hasan Department of Cardiology and Vascular Medicine, Faculty of Medicine University of Sumatera Utara, Haji Adam Malik General Hospital, Medan, Indonesia Background: Whether a precordial ST segment depression (PSTD) is merely a benign electrical phenomena or a sign of multivessel coronary artery disease (MVCAD) in inferior myocardial infarction (MI) remains unclear. The objective of this study is to analyze the complexity of coronary artery disease (CAD) in inferior MI patients with PSTD and to investigate whether PSTD can be used as a predictor of MVCAD in inferior MI. Methods: Patients with inferior MI were divided into two groups based on the presence of PSTD on admission ECG and were compared based on the patientâ€™s coronary artery complexities. Results: A total of 215 patients with inferior MI were found in this study period, with 102 patients meet the inclusion and exclusion criteria. Patients with PSTD had a higher incidence of MVCAD and SYNTAX score. Further analyzes showed PSTD on admission ECG was an independent predictor of MVCAD in inferior MI [45 (66%) vs 23 (34%); OR 4.097; 95% CI 1.638-10.247; p=0.003). Conclusion: In daily clinical practice, PSTD on admission ECG may serve as a simple noninvasive tool for predicting MVCAD or a more complex CAD in inferior MI. Keywords: Precordial ST Segment depression, inferior myocardial infarction, SYNTAX score

Gambaran Hasil Pemeriksaan Ekokardiografi Pasien Gagal Jantung di RSUP H. Adam Malik pada Tahun 2021 Trifena Aurelya Rimna Surbakti; Anggia Chairuddin Lubis
SCRIPTA SCORE Scientific Medical Journal Vol. 5 No. 1 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v5i1.10867

Pendahuluan. Angka kejadian penyakit gagal jantung masih terus meningkat di tingkat global. Dalam mendiagnosis dan mengevaluasi penyakit gagal jantung, terdapat beberapa modalitas yang dapat diandalkan, salah satunya adalah ekokardiografi. Metode pemeriksaan ekokardiografi berguna dalam banyak aspek termasuk penilaian fungsi dan diameter jantung, yang secara klinis menjadi landasan dalam pilihan pengobatan dan prognosis penderita gagal jantung. Tujuan. Tujuan penelitian ini adalah untuk mengetahui gambaran hasil pemeriksaan ekokardiografi pasien gagal jantung di RSUP H. Adam Malik Medan pada tahun 2021. Metode. Penelitian ini memiliki desain deskriptif retrospektif dengan pendekatan potong lintang (cross sectional). Hasil. Mayoritas penderita berasal dari kalangan usia produktif. 73,62% pasien berjenis kelamin laki-laki. Etiologi terbanyak pada penelitian ini adalah penyakit iskemik. Ditemukan 49,08% sampel mengalami hipertrofi eksentrik, 46,63% mengalami hipertrofi konsentrik, 1,84% mengalami remodelling konsentrik, dan 2,45% memiliki geometri LV yang normal. Rata rata LVEF adalah 44,70% dengan HFpEF yang paling mendominasi. 77,30% memiliki TAPSE normal dan dari 121 data yang tersedia, 46,63% mengalami disfungsi diastolik grade I, 14,72% mengalami disfungsi diastolik grade III, dan sisanya, 12,88% mengalami disfungsi diastolik grade II. Kesimpulan. Kebanyakan pasien gagal jantung di RSUP H. Adam Malik Medan pada tahun 2021 berasal dari kalangan usia produktif. Etiologi tersering adalah penyakit iskemik. Dimensi dan volume LV mayoritas pasien hipertrofi eksentrik. HFpEF mendominasi dan TAPSE kebanyakan normal. Dari 121 data mengenai disfungsi diastolik LV, disfungsi grade I merupakan yang terbanyak. Kata Kunci: gagal jantung, ekokardiografi, LVEF, TAPSE, gambaran

Measurement of Thoracic Aortic Diameter Using Contrast-Enhanced CT Chest Based on Age, Gender, and Hypertension Irma, Ade; Daulay, Elvita Rahmi; Lubis, Anggia Chairuddin
Journal of Society Medicine Vol. 2 No. 3 (2023): March
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i3.39

Introduction: CT is widely used to evaluate patients with aneurysm or aortic dissection. Therefore, it is very important to assess accurate aortic size in detecting aneurysm and dissection. The thoracic aortic diameter varies depending on the measurement level. Several demographic factors affect the thoracic aorta diameter such as age and gender. Risk factors for cardiovascular disease such as hypertension also have a relationship with the diameter of the thoracic aorta. To determine the difference of thoracic aorta diameter based on age, sex, and history of hypertension in patients with contrast-enhanced CT chest. Method: A case-control study in 140 patients with contrast-enhanced CT chest without signs or symptoms of car¬diovascular diseases. Thoracic aortic diameters were measured at seven predetermined levels on CT images. Analysis of data was performed with regard to age, sex, and hypertension. Results: The mean diameters of the thoracic aorta at the level of the aortic valve sinus is 3.06 ± 0.39 cm, ascending aorta 2.90 ± 0.39 cm, proximal to innominate artery 2.73 ± 0.39 cm, transverse aortic arch 2.53 ± 0.38, distal transverse aortic arch 2.37 ± 0.35, aortic isthmus 2.17 ± 0.33, and descending aorta at the level of diaphragm 1.91 ± 0.33 cm. There is a significant difference in all thoracic aortic diameters based on age and gender on statistical analysis (p<0.001). There is a significant difference in all thoracic aortic diameters between subjects with history of hypertension and without history of hypertension, except at the level of transverse aortic arch (p<0.051). Conclusion: There is a difference in the mean thoracic aortic diameter at each level of measurement based on age, sex, and history of hypertension in patients with contrast-enhanced CT chest.

Correlation of P Wave Dispersion and Quality of Life of Heart Failure Due to Coronary Heart Disease Patient in Haji Adam Malik General Hospital Hillary, Lastri; Nasution, Ali Nafiah; Lubis, Anggia Chairuddin
Journal of Society Medicine Vol. 3 No. 4 (2024): April
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i4.138

Introduction: P wave dispersion is a more sensitive cardiovascular marker which obtained by the ECG to elaborate structural and electrophysiological abnormalities in patients. This study aims to elucidate P wave dispersion prevalence in heart failure due to coronary heart disease patients and the correlation with their quality of life. Method: This analytical cross-sectional study is done in RSUP Haji Adam Malik in 133 patients with heart failure from May to June 2023. Patients had undergone clinical evaluation, physical examination, 12-lead electrocardiography (ECG), and then were given the MLFHQ to assess the quality of their lives. Data were analyzed using fischer-exact test, with p value less than 0.05 considered to be significant. Results: From the total of 133 sample of patients, there were 55 (43.2%) patients with positive p wave dispersion, among them 2 had low quality of life, 25 had moderate quality of life, and 28 had good quality of life. With mean of PWD is 27.9±15.1 ms. The group of patient with negative p wave dispersion 78 had moderate and good quality of life. P value is less than 0.01. It’s concluded that there was a positive correlation between p wave dispersion and quality of life of heart failure patients in Haji Adam Malik general hospital Conclusion: There is positive correlation between p wave dispersion and quality of life of heart failure due to coronary heart disease patients in Haji Adam Malik general hospital.

Premature Ventricular Complexes: Diagnose, Evaluation, and Management Handayani, Ahmad; Lubis, Anggia Chairuddin
Buletin Farmatera Vol 7, No 1 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i1.9684

Premature ventricular complexes (PVCs) are arrhythmias due to abnormal impulse formation in the ventricles. The incidence is detected as much as 1% on standard electrocardiographic (ECG) examination. The aim of this literature review is to explain the diagnosis, evaluation, and management of PVC. The diagnosis of PVC is determined from the symptoms and evidence from the ECG recording. Symptoms may include a faster heartbeat sensation, chest discomfort, skipped beat, and intermittenly strong heartbeat. Evidence of PVC is established by regular ECG recordings or Holter. A 12-ECG can help determine the location of source. PVC evaluation includes determine the dangerousity, the next examination step, the treatment options, and whether ablation is needed. Managements include medical therapy and catheter ablation. Catheter ablation is performed where treatment is unsatisfactory or if the PVC causing life threathening arrhythmia or cardiomyopathy. PVC is considered dangerous if the underlying disease is found in the form of cardiac structural abnormalities, ischemic heart disease or other arrhythmic disorders, more than 2000 PVC is found in 24 hours, complex morphology, different morphology, increased with exercise, PVC with non-outflow tract form, with short coupling interval, and with a wider QRS duration The incidence of VVC that is considered to be able to induce cardiomyopathy is from 10-26%. PVC requires a structured and systematic diagnosis and evaluation step to determine the appropriate treatment.

Hubungan Peak Left Atrial Longitudinal Strain dengan Derajat Keparahan Penyakit Jantung Katup Mitral di RSUP Haji Adam Malik Medan Ryanti, Dina; Ketaren, Andre Pasha; Mukhtar, Zulfikri; Akbar, Nizam Zikri; Lubis, Anggia Chairuddin; Ardini, Tengku Winda
Jurnal Kardiologi Indonesia Vol 44 No 2 (2023): Indonesian Journal of Cardiology: April - June 2023
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1541

Introduction: Mitral stenosis and regurgitation, are common throughout the world. Peak Left Atrial Strain (PALS) is a parameter for assessing left atrial deformation in the evaluation of atrial function and a predictor of long-term outcome of various heart diseases. In this study, we assessed the relationship between PALS and the severity of mitral stenosis and mitral regurgitation Methods: This is a cross-sectional study on 119 subjects with mitral stenosis and 103 mitral regurgitation who met the inclusion criteria at Haji Adam Malik General Hospital. PALS measurements were taken. Data were analyzed univariate, bivariate, correlate to assess the relationship between PALS and the severity of mitral valve disease Results: 119 patients with severe mitral stenosis. In mitral stenosis, the mean PALS is 8.2 (4.9-22.8). PALS was significantly higher in patients with sinus rhythm than in the group with AF (10.29 ± 3.89 vs 8.63 ± 7.8%; P = 0.002). PALS had a significant correlation with MVA, pressure gradient, and PHT (r = 0.676, P = <0.001; r=-0.594, P= 0.001 and r=-0.594, P= 0.001). Whereas in mitral regurgitation, it has an average PALS of 15.2 (7.8-19.2). PALS was also significantly higher in patients with sinus rhythm than in the group with AF (16.36 ± 2.43 vs 11.64 ± 2.89%, P = 0.001). PALS has a correlation with VC, PISA, EROA and RVol (r = -0.533, P=0.001; r=-0.618; r=-0.563, P=0.001; r= -0.528, P=0.001). Conclusion: PALS has a significant correlation with the assessment of the severity of mitral stenosis and regurgitation.

Prevalence of Congenital Heart Disease and Pediatric Rhythm Disorder or Arrhythmia in Children in Rantau-Prapat City, North Sumatra, Indonesia Lubis, Anggia Chairuddin; Nasution, Ali Nafiah; Lubis, Hilfan Ade Putra
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 4 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i4.14332

Background: Cardiovascular diseases (CVD) are responsible for the leading cause of a 30% global mortality rate and are a major contributor to reducing the quality of life. Approximately 25% of the cardiovascular mortality rate is caused by sudden cardiac deaths and cardiac arrhythmias are one of the causes of sudden cardiac deaths. Besides that, Congenital Heart Disease (CHD) also contributes mortality rate in children. Long-term experience has provided evidence that systematic screening, with 12-lead ECG, after history and physical examination, is effective in identifying individuals with potentially lethal cardiovascular disease for early intervention. However, in Indonesia screening for heart abnormalities and rhythm disorder in children has not yet been systematically established. Method: This study was a descriptive study conducted through a cross-sectional study design. The primary objective was to assess the congenital heart disease (CHD) and Arryhtmia prevalence in children in Rantau City. Data was collected from interviews and on-the-spot examination with validated measurement tools. Data was analyzed using SPSS version 26. Categorical variables were presented using frequency (n) and percentage (%), and numerical variables with normally distributed data were presented with mean and standard deviation (SD). In non-normally distributed data, numerical variables were presented using the median and interquartile range. Results: There were 157 children included in this study. Most subjects were female (n=94, 59.9%) in the age range of 12 to 16 years old. Most subjects (n=129, 82.2%) had normal sinus rhythm. The only rhythm disorder that was found in this study was sinus tachycardia (n=28, 17,8%). One subject (0,9%) had congenital heart disease, which was a secundum atrial septal defect. Conclusion: In the children population in Rantau-Prapat city, the most common arrhythmia found in children was sinus tachycardia. The atrial septal defect was the only congenital heart disease found.

Co-Authors Abdul Halim Raynaldo Abdullah Afif Siregar Abdullah Afif Siregar Achmad, Aziz Ade Irma Ahmad Handayani Akbar, Nizam Zikri Ali Nafiah Nasution Ali Nafiah Nasution Andra, Cut Aryfa Andra, Cut Aryfa andrico tobing Ardini, Tengku Winda Ariestine, Dina Aprilia Asepty, M. Rizky Priyanka Batubara, Gio Justisia Brahmana, Andrew Timanta Cut Aryfa Andra Daulay, Elvita Rahmi Dewita, Auliya Edison Bun Ferhat, Muhammad Hana Fauziyah Harris Hasan Harris Hasan Hasan, Harris Hasan, Harris Hasan, Refli Hillary, Lastri Ilyas, Kamal Kharazzi Irawan, Raja Alfian Jaya Suganti Karo, Kartika br Ketaren, Andre Pasha Ketaren, Andre Pasha Khairunnisah, Dina Lubis, Hilfan Ade Putra Mukhtar, Zulfikli Mukhtar, Zulfikri Nadiah Masyab Napitupulu, Bertha Gabriella Nasution, Ali Nafiah Nasution, Melati Silvanni Nizam Zikri Akbar Purba, Joy Wulansari Raynaldo, Abdul Halim Refli Hasan Ryanti, Dina Safri, Zainal Sarastri, Yuke Siregar, Abdullah Afif Sitepu, Andika Sutomo Kasiman Taufik Sungkar, Taufik Teuku Bob Haykal Trifena Aurelya Rimna Surbakti Yasmine Fitrina Siregar Yuke Sarastri

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