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All Journal Journal of Midwifery and Nursing Jurnal Kesehatan Farmasi
Hepni Hepni
Sekolah Tinggi Ilmu Kesehatan (STIKes) Arjuna Laguboti
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Tlc Profile And Antifungal Activity Test Of Ethylacetat Extract Of The Flower Moon Herbs (Tithoniadiversifolia (Hemsl.) Gray) Againts Candida Albicans And Microsporum Canis Hepni Hepni; Fitri Yanti; Faisal Yusuf
Journal of Midwifery and Nursing Vol. 4 No. 2 (2022): Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v4i2.2183

Abstract

The moon flower herb is a plant species known and used as traditional medicine in Indonesia for generations. In previous studies it was known that moonflower (Tithonia diversifolia (Hemsl) Gray) has antihyperglycemic, antidiabetic, antimicrobial and antimalarial effects, and it is known that the roots, stems, leaves and essential oil of moonflower (Tithonia diversifolia (Hemsl) Gray) contain alkaloids, compounds phenolics, steroids, saponins and flavonoids. The purpose of this study was to determine the activity of ethylacetate extract of moonflower herb against Candida albicans and Microsporum canis. This research was carried out in several stages, starting with the process of collecting and processing samples, testing the characteristics of simplicia, maceration of the ethylacetate extract of the moonflower herb (Tithonia diversifolia (Hemsl) Grey), testing Thin Layer Chromatography (TLC) and testing antifungal activity. The results of the research that the moon flower herb has a water content of about 10.2%. Thin Layer Chromatography (TLC) test of moonflower herbs on ethyl acetate extract containing polyphenolic compounds, steroids and alkaloids. The minimum inhibitory concentration (MIC) of ethylacetate extract of moonflower herb against Candida albicans ATCC 10231 was at a concentration of 200 mg/mL, ie 3.00 mm, while in Microsporum canis it was found at a concentration of 300 mg/mL. which is equal to 13.21mm.
Pola Peresepan Obat Antihipertensi Pada Pasien BPJS Kesehatan di Apotek Kimia Farma Ahmadyani Faisal Yusuf; Hepni Hepni; Ully Widya Rochmatil Ulla
Jurnal Kesehatan Farmasi Vol 4, No 2 (2022)
Publisher : Jurusan Farmasi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (665.179 KB) | DOI: 10.36086/jpharm.v4i2.1451

Abstract

Latar Belakang: Hipertensi merupakan “silent killer” ( pembunuh diam-diam) yang secara luas dikenal sebagai penyakit kardiovaskular yang sangat umum. Dengan meningkatnya tekanan darah dan gaya hidup yang tidak seimbang dapat meningkatkan faktor resiko munculnya berbagai penyakit seperti jantung, gagal ginjal dan stroke. Sampai saat ini, hipertensi masih merupakan tantangan besar di Indonesia. Metode: Design penelitian ini bersifat deskriptif dengan pendekatan waktu retrospektif, dengan sampel resep sebanyak 240 resep, dengan tehnik pengambilan sampel simple random sampling. Hasil : Hasil penelitian menunjukkan bahwa antihipertensi yang paling banyak digunakan adalah golongan antagonis kalsium yakni 128 kasus (52,67%), kombinasi antihipertensi yang paling sering diberikan adalah kombinasi ARB dan antagonis kalsium yaitu sebanyak 71 kasus (53,79%). Penderita hipertensi terbanyak berdasarkan usia yaitu usia 66 tahun keatas yaitu 97 kasus ( 39,92%), dan Penderita hipertensi yang berjenis kelamin perempuan lebih dominan terkena hipertensi yakni 138 kasus(56.79%). Kesimpulan: Persentase perbandingan jumlah peresepan obat antihipertensi terapi kombinasi dan terapi tunggal pada pasien BPJS di Apotek Kimia Farma Ahmadyani Pematang Siantar. Jumlah penggunaan obat tunggal yakni 110 kasus (45,27%) dan 133 kasus (54,73%) yang menggunakan obat kombinasi.
Co-Authors Faisal Yusuf Faisal Yusuf Fitri Yanti Ully Widya Rochmatil Ulla