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Miranti Candrarisna
Fakultas Kedokteran Hewan Universitas Wijaya Kusuma Surabaya
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology

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Uji sensitivitas anti bakteri dan anti jamur terhadap megabacterium secara in vitro Miranti Candrarisna; Edi Boedi Santosa; Sudarmanto Indarjulianto; Surya Amanu
VITEK : Bidang Kedokteran Hewan Vol 5 (2015): VITEK - Bidang Kedokteran Hewan
Publisher : Fakultas Kedokteran Hewan Universitas Wijaya Kusuma Surabaya

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Abstract

Uji sensitivitas terhadap bakteri megabacterium penyebab Megabacteriosis pada burung import dilakukan dengan menggunakan beberapa anti bakteri seperti : Ampisillin, Enrofloksasin, Eritromisin, Klindamisin, Kloramfenikol, Streptomisin, dan Tetrasiklin. Sedangkan anti jamur yang digunakan : Griseofulvin, Ketokonazol dan Nystatin. Penelitian ini bertujuan mengkaji potensi obat anti bakterial dan anti jamur terhadap megabacterium. Penelitian dilakukan di Laboratorium Mikrobiologi dan Virologi Fakultas Kedokteran Hewan Universitas Gadjah Mada. Pengujian sensitivitas beberapa obat anti bakterial dan anti jamur dilakukan dengan menggunakan agar disc diffusion method (metode penghambatan cakram dish pada media Muller Hilton Agar plat) secara in vitro. Pengamatan dilakukan pada suhu 370C selama 24-48 jam dalam suasana anaerob. Hasil pengamatan berupa pembentukan diameter zona hambatan di sekitar kertas cakram. Hasil penelitian yang diperoleh dianalisis secara deskriptif. Hasil penelitian menunjukkan: megabacterium resistensi terhadap Ampisillin, dan megabacterium sangat sensitif terhadap Griseofulvin, kemudian diikuti Enrofloksasin, Klindamisin, Kloramfenikol, Nystatin, Ketokonazol, Eritromisin, Tetrasiklin dan Streptomisin.
Perbandingan efektifitas talcum, unguentum, dan pasta ekstrak terstandar kulit manggis (garcinnia mangostana linn) terhadap ringworm disease (tinea corporis) Miranti Candrarisna
VITEK : Bidang Kedokteran Hewan Vol 6 (2016): VITEK - Bidang Kedokteran Hewan
Publisher : Fakultas Kedokteran Hewan Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jv.v6i0.25

Abstract

Purpose of this study was to compare the effectiveness of talcum, unguentum and paste of mangosteen peel extract standardized (Garcinnia mangostana Linn) against Ringworm Disease in vivo. This type of experimental research using completely randomized design. The research sample: male hamster 24 animals, divided 4 groups and 6 replications: a control group, were infected ringworm fungus (Trycophyton mentagophytes) but not given treatment (P0), the treatment group infected ringworm fungus and treated with talcum extract standardized mangosteen rind (P1) treatment group and the untreated ringworm fungus infected unguentum standardized extract of mangosteen peel (P2), a group that ringworm fungus infected and treated with a paste of mangosteen peel extract standardized (P3). Giving a fungal infection ringworm done once, then wait 1-2 weeks until the fungal infection spread to the whole body of experimental animals were then treated according to the treatment dose of 50% twice a day. Observation of wound healing, change in body surface area that has been infected with mildew, scab and reduction of area small dots such as rings and mushrooms are native examination conducted on the 5th, 10th and 15th. Results of the examination of the wound healing, change in body surface area that has been infected with mildew, scab and reduction of area small dots like ring diskoring and analyzed by Analysis of Variance (ANOVA). The results showed: the treatment group was given a fungal infection ringworm and treated with a paste of mangosteen peel extract standardized to 50% dose twice daily (P3) provide most excellent and effective than the group P2, P1 and P0 appears on the 15th day.
Co-Authors Edi Boedi Santosa Sudarmanto Indarjulianto Surya Amanu