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Zulvia Faridatul Munawaroh
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Darussalam Gontor

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Uji Efektivitas Seduhan Kopi Biji Okra (Abelmoschus esculentus) terhadap Penurunan Kadar Glukosa Darah pada Mencit yang diinduksi Aloksan Zulvia Faridatul Munawaroh; Rahmat A.H. Wahid; Nurul Marfu'ah
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 3, No 2 (2019): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (481.44 KB) | DOI: 10.21111/pharmasipha.v3i2.3405

Abstract

Diabetes mellitus is a degenerative disease characterized by high blood glucose levels. Various ways that people use for treatment, herbal is one of the choices. God will not create an illness unless Him has created the medicine. One of the plants that is often used to treatment diabetes mellitus is okra plants. Okra seeds could be processed into coffee which is used as a substitute for caffeinated coffee. Based on community experience, so this research to know the effectiveness test of steeping coffee from okra (Abelmoschus esculentus) seeds in alloxan-induced diabetic mice and to know the effective concentration of steeping coffee from okra (Abelmoschus esculentus) seeds in alloxan-induced diabetic mice. This research was an experimental study. The research design used was a Completely Randomized Design (CRD) consisting of 4 treatments and 4 replications. The sample consisted of 16 male mice. The study was divided into 4 groups, The sample consisted of16 male mice and divided into 4 group, giving aquadest as a positive control (PC) while in treatment T1 by giving steeping coffee from okra seeds with a concentration of 1.82 mg/grBW/day, 3.64 mg/grBW/day for T2 and T3 with a concentration of 5.46 mg/mgBW/day for 10 days . Data were analyzed using the SPSS 16.0. According to the results of the One Way ANOVA test with a significance level of 95% were obtained at 0,000 (p = <0.05) which means that, between treatments given by okra seeds coffee, okra seeds coffee were effective against blood glucose levels of mice after alloxan was induced. Based on the three treatments for the administration of okra seeds coffee with various concentrations, group T3 (5.46 mg/mgBW/day) with a significance value of 0,000 (p<0.05) which was the most effective for reducting blood glucose levels in alloxan-induced diabetic mice.
Uji Aktivitas Antibakteri Ekstrak Etanol Biji Mangga (Mangifera indica L.) terhadap Propionibacterium acnes Zulvia Faridatul Munawaroh
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 1, No 1 (2017): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v1i1.1122

Abstract

This study aims to utilize mango seed waste and to determine the antibacterial activity of the mango seed. Utilization of mango seeds can be used as an alternative to prevent and treat acne due Propionibcterium acnes.In this study tested the in vitro antibacterial activity against Propionibacterium acnes bacteria. Crude drug percolation mango seed made with ethanol, antibacterial activity of mango seed extract was tested by paper disc diffusion method to determine the value of Minimal Inhibitory concentration (MIC).The ethanol extract mango seed with a concentration of 60% or 0,6g / ml ethanol extract of mango seed has inhibitory zone up to 13.67 mm, at a concentration of 40% or 0,4g / ml extract menghasilkan10,1 mm and at a concentration of 20% or 0,2g / ml extract resulted in inhibition zone diameter of 10.43 mm contained in Kisara 10-20 mm. The ethanol extract mango seed has antibacterial effectiveness against bacteria Propionibacterium acnes that is strong enough. are expected to inhibit the growth of bacteria that causes acne so as to prevent and eliminate acne.