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Hakimi Hakimi
Department of Child Health, University of Sumatera Utara Medical School/H. Adam Malik Hospital, Medan, North Sumatera
Health Professions Medicine & Pharmacology

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Body mass index and age of menarche in young girls Dina Olivia; Melda Deliana; Supriatmo Supriatmo; Hakimi Hakimi; Siska Mayasari Lubis
Paediatrica Indonesiana Vol 52 No 6 (2012): November 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.239 KB) | DOI: 10.14238/pi52.6.2012.309-12

Abstract

Background Currently the age at onset of menarche is earlierthan in the past. Nutritional status has an important role inthe onset of menarche. Past studies have shO\vn an associationbetween body mass index (BMI) in young girls and earlier onsetof menarche.Objective To assess an association between BMI and age at onsetof menarche.Methods This cross􀁈sectional study was conducted in younggirls aged 10 to 15 years from Immanuel Elementary and JuniorHigh School, Medan in June 2010. We used purposive samplingto recruit subjects. After subjects underwent height and weightmeasurements, we calculated their BMIs. The association betweenBMI and initial age of menarche was assessed by Chi square test(P<O.05 v.ith a 95% confidence interval).Results Eighty􀁈five subjects participated in this study. There were44 subjects in the 5th􀀊85th percentile ofBMI (nonnoweight), 19subjects with 85th􀀊95th percentile of BMI (overweight) and 12subjects in the> 95th percentile ofBMI (obese). All obese subjectshad an earlier onset of menarche at ages 1O􀁈 11 years, comparedto that of non􀁈obese subjects (P=O.OOOl).Conclusion Young girls v.ith BMI > 95th percentile had anearlier age at onset of menarche than young girls v.ith lower BMls.[Paediatr lndanes. 2012,52:309-12].
Effectiveness of vitamin E as a treatment of primary dysmenorrhea in pubertal adolescents Wagito Wagito; Siska Mayasari Lubis; Melda Deliana; Hakimi Hakimi
Paediatrica Indonesiana Vol 51 No 1 (2011): January 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi51.1.2011.41-6

Abstract

Background Primary dysmenorrhea is a common complaint among adolescents. Absenteeism from work and school are associated with the severity of symptoms. Vitamin E is an alternative treatment for primary dysmenorrhea.Objective To evaluate the effectiveness of vitamin E as a treatment of primary dysmenorrhea.Methods We conducted a randomized, double-blind, controlled trial from August to October 2009. We included female adolescents 'With primary dysmenorrhea in this study. Subjects were divided into 2 groups by simple randomization. Each group received either 200 units of vitamin E or a placebo twice daily, beginning two days before menstruation and continuing until the third day of menstruation. Treatment was repeated for three menstrual cycles. Subjects recorded the severity and duration of pain in a daily diary. Data was analyzed using Chi􀁍square, Mann􀁍W hitney U􀁍test, and independent T-test.Results One hundred􀁍sixteen primary dysmenorrhea subjects enrolled in our study. By simple randomization, they were divided into two groups of 58 subjects each. There were no statistically significant differences between the two groups in the severity and duration of pain before the start of treatment and after 1 month of treatment. After treatment for 2 months and 3 months, there were statistically significant differences in pain severity (P=0.013, 95%CI -0.54 to -0.11; and P=0.0001, 95%CI -0.67 to -0.26, respectively) and pain duration (P=0.025, 95%CI -0.65 to -0.07 and P=0.007, 95%CI -0.75 to -0.12, respectively) between the 2 groups.Conclusion Vitamin E was effective in treatment of primary dysmenorrhea in pubertal adolescents after 2 and 3 months of treatment.
Effectiveness of amitriptyline for treating functional dyspepsia in adolescents Indra Mustawa; Supriatmo Supriatmo; Hakimi Hakimi; Atan Baas Sinuhaji
Paediatrica Indonesiana Vol 56 No 5 (2016): September 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.899 KB) | DOI: 10.14238/pi56.5.2016.262-6

Abstract

Background Functional dyspepsia is common among adolescents. Pain reduces children’s quality of life, psychosocial functioning, and school attendance. Amitriptyline is assumed to be one of the alternative treatments in functional dyspepsia.Objective To investigate the effectiveness of amytriptyline as a treatment  for  functional dyspepsia in adolescents.Methods We conducted a randomized, single-blind, controlled trial from January to March 2011 in junior and senior high school students in Dobo City, Aru Island District, Maluku Province. Adolescents suffering from functional dyspepsia and who fulfilled the inclusion criteria were eligible for the study. Subjects were randomized into two groups. Each group received 10 mg (for body weight < 35 kg) or 20 mg (for body weight ≥ 35 kg) amitriptyline or placebo once per day for 28 days. Pain frequency was measured in terms of abdominal pain episodes per month, and duration was measured in minutes. Data were analyzed using t-test.Results Eighty-eight students participated in this study: the amitriptyline group (43 subjects) and the placebo group (45 subjects). There were no statistically significant differences between the amitriptyline and placebo groups in frequency (P=0.777; 95%CI -0.846 to 1.129) or duration (P=0.728) of abdominal pain after treatment.Conclusion  Amitriptyline is not more effective than placebo for treating functional dyspepsia in adolescents.  
Co-Authors Atan Baas Sinuhaji, Atan Baas Dina Olivia Indra Mustawa Melda Deliana Siska Mayasari Lubis Supriatmo Supriatmo Wagito Wagito