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Imam Boediman
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Health Professions Medicine & Pharmacology

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Characteristics of HIV-infected children born to HIV-positive mothers in Cipto Mangunkusumo Hospital between 2002 and 2007 Fransisca Mayer; Arwin Akib; Imam Boediman
Paediatrica Indonesiana Vol 49 No 2 (2009): March 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (125.055 KB) | DOI: 10.14238/pi49.2.2009.112-8

Abstract

Background In 2003, the Joint United Nation Program onHIV/AIDS and the World Health Organisation estimatedthat there will be 36.2 million people living with HIV /AIDSthrougout the world by the end of2003, and that 2.1 millionof them will be children less than 15 years old. The profileof children with HIV in the Department of Child Health,Cipto Mangunkusumo Hospital has not been studied.Objective To identify the characteristics of HIV-infectedchildren born to HIV-positive mothers, and to evaluate thePrevention Programme for Mother-to-Child Transmissionat Cipto Mangunkusumo Hospital.Methods This was a cross-sectional study conductedbetween March and May 2008 based on medical records.The study population consisted of all mother-child pairswho were admitted between January 2002 and December2007.Results Between 2002 and 2007,342 children were born toHIV-infected mother, with 201 (58.5%) children contractingHIV The median age of children was 20 months. Therewere 121 (35.4%) cases involved in prevention of motherto-child transmission. Triple-drug antiretroviral therapywas prescribed to 78.1 o/o children. The most frequentmorbidities were chronic diarrhea, wasting syndrome, andoropharyngeal candidiasis. Thirty-six children died; mostlydue to sepsis (30.5%)Conclusion The majority of cases of HIV were between 1and 5 years old. The most frequent morbidities were chronicdiarrhea, wasting syndrome, and oropharyngeal candidiasis.Thirty-six children died mostly due to sepsis. The preven-tion program for mother-to-child transmission should beencouraged among pregnant women who are known to beHIV-positive.
Effect of inhaled procaterol and budesonide on right ventricular diastolic function in children with asthma Alit Utamayasa; Najib Advani; Imam Boediman; Sudigdo Sastroasmoro; Bambang Madiyono
Paediatrica Indonesiana Vol 49 No 3 (2009): May 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (142.917 KB) | DOI: 10.14238/pi49.3.2009.131-4

Abstract

Objectives To study changes in parameters of right ventricular(RV) diastolic function after procaterol and budesonide inhalationin children with asthma.Methods This was a one-group pretest-posttest design to determinechanges in right ventricular diastolic function followingfour weeks of inhaled procaterol and budesonide administration.Subjects were children aged 8 to 18 years with frequent episodicasthma recruited consecutively at the Department of ChildHealth, Cipto Mangunkusumo Hospital. M-mode and 2-Dechocardiography examinations were performed to determine RVisovolumetric relaxation time (IVRT), acceleration time (AT),deceleration time (DT), E wave, A wave, E/ A ratio, and tricuspidannular plane systolic excursion (TAPSE). Means of the RVfunction parameters before and after treatment were comparedusing the paired t-test or Wilcoxon test.Results There were 29 patients comprising 16 boys and 13 girls. Themeans or medians of theE wave, A wave, E/A ratio, accelerationtime (AT), deceleration time (DT), and isovolumetric relaxationtime (IVRT) before and after treatment were 0.55 and 0.55 em/sec(P=0.709), 0.45 and 0.35 em/sec (P<O.OOOl), 1.17 and 1.58 em/sec(P<0.0001), 52.73 and 55.03 m/sec (P=0.04), 55.39 and 58.10 m/sec (P=0.03), and 46.50 and 70.0 m/sec (P<0.0001), respectively.The median pre- and post-inhalation TAPSE were 1.63 and 1.84em, respectively (P<0.001).Conclusions In children with frequent episodic asthma, thereare changes in RV diastolic functions IVRT, AT, DT, E/A ratioand A wave following procaterol and budesonide inhalation.There was no increase in E wave following inhalation. TAPSEwas increased following procaterol and budesonide inhalation.
Co-Authors Alit Utamayasa Arwin Akib Bambang Madiyono Fransisca Mayer Najib Advani Sudigdo Sastroasmoro