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All Journal Paediatrica Indonesiana Alami Journal (Alauddin Islamic Medical) Journal
Martira Maddeppungeng
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Education Health Professions Medicine & Pharmacology

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Dermatoglyphic patterns of goitrous children in endemic iodine deficiency area Martira Maddeppungeng; R Satriono
Paediatrica Indonesiana Vol 44 No 3 (2004): May 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (683.896 KB) | DOI: 10.14238/pi44.3.2004.117-20

Abstract

Background Goiter mapping on elementary school students in1998 showed that the prevalence of endemic goiter was still highat Enrekang regency, South Sulawesi despite various programs tomanage this problem. This raised questions if there were any otherfactors that contribute to the occurrence of goiter e.g. genetic fac-tor, which can be assessed indirectly by dermatoglyphic pattern.Objective To determine the dermatoglyphic pattern in goitrouschildren and compare it to normal children.Methods A cross sectional study was done to investigate the cor-relation between goiter and dermatoglyphic patterns on 115 el-ementary school students at Anggeraja and Baraka subdistricts,Enrekang regency. Dermatoglyphic patterns of finger tips of bothhands and right hallux were scanned using Prolink scanner withMaximum Resolution of 19200x19200dpi and interpreted usingphoto/image editing computer program.Results Seventy two (62.6%) of 115 children were goitrous, sev-enty (97%) were of stage1, and 2 (3%) of stage 2. No significantdifference was found in dermatoglyphic patterns between normaland goitrous children. Tibial loop pattern of the right hallux tendedto be more frequent in goitrous children than that of normal chil-dren, but it was not statistically different (in level of significancy of0.05) compared to normal children (p=0.085).Conclusions This study indicates that the possibility of the role of ge-netic factor in the development of goiter in endemic area is unlikely
Beyond Ear Discharge: Multisystem Langerhans Cell Histiocytosis with Temporal and Calvarial Involvement in a Child Nadirah Rasyid Ridha; A Alfiah Mutmainnah; Martira Maddeppungeng
Alami Journal (Alauddin Islamic Medical) Journal Vol 10 No 1 (2026): JANUARY
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/alami.v10i1.62266

Abstract

Introduction: Langerhans cell histiocytosis (LCH) is a rare clonal myeloid neoplasm that commonly affects the bone and skin in children. Temporal bone involvement is uncommon and often mimics chronic otitis media, which may lead to delayed diagnosis. Case Presentation: We report a 4-year-5-month-old girl who presented with persistent right ear discharge and a visible mass in the external auditory canal for four months. Physical examination revealed diffuse papular and crusted lesions on the scalp and trunk, along with frequent nocturnal urination. The patient had a previous history of right ear tumor excision and parietal craniotomy. Histopathological analysis confirmed Langerhans cell histiocytosis, supported by positive S-100 immunohistochemical staining. Imaging demonstrated a soft-tissue mass obliterating the external ear canal and a parieto-occipital lesion with osseous destruction but no intracranial extension. The patient received vincristine and prednisone chemotherapy following the LCH-IV protocol, resulting in significant clinical improvement. Conclusion: Temporal bone LCH may clinically resemble chronic ear disease. Early recognition through biopsy and immunohistochemistry is crucial for establishing the diagnosis and initiating timely systemic therapy, thereby improving long-term outcomes.
Co-Authors A Alfiah Mutmainnah Nadirah Rasyid Ridha, Nadirah Rasyid R Satriono