Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal The Indonesian Biomedical Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Sandhy Prayudhana
Faculty of Medicine University of Indonesia/ Dr. Cipto Mangunkusumo National General Hospital Jakarta
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Maternal and Fetal Outcome on Pregnancy in Advanced Maternal Age Dewi, Sianty; Ferry, Ferry; Toynbee, Eddy; Prayudhana, Sandhy
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No.3, July 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.874 KB) | DOI: 10.32771/inajog.v4i3.432

Abstract

Objective: Pregnancy in advanced maternal age (AMA) was classified as high risk. The study aims to provide a better description of pregnancy outcome in AMA. Method: The cross sectional study was to review the demography, medical and obstetrics problems, mode of delivery, maternal and fetal outcome in Tangerang General Hospital as a referral center in Banten. The data were taken from medical records of 35-year-old and above women age who delivered on the period of January to December 2014. Result: The total number of delivery and live birth was 6,107 and 5,926 respectively, including 1,548 (25.36%) pregnancies in AMA. The prevalence of grandmultiparities was 11.4%. The average education level was mostly elementary. The prevalence of hypertension in pregnancy was 34.6%. There was increasing trend of miscarriages from 10.8% in 35-40-year-old group to 25% in above 45- year-old group. Pregnancy complications were higher consisting of 3.2% multifetal, 16.6% malpresentation, and 7.1% placenta previa. Cesarean section rate was 33.6%. Maternal near-missed cases were 56 of 1000 and the maternal mortality rate (MMR) was 932 of 100,000 live births. The prevalence of stillbirth and perinatal mortality were 5.3% and 12.9%; respectively. Conclusion: Adverse maternal and fetal outcome were higher in AMA as it takes special attention and multidiscipline-approached care started from preconception, antenatal, preparation of delivery, and also postpartum care. Keywords: advanced maternal age (AMA), fetal outcome, maternal outcome, pregnancy
Maternal and Fetal Outcome on Pregnancy in Advanced Maternal Age Dewi, Sianty; Ferry, Ferry; Toynbee, Eddy; Prayudhana, Sandhy
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No.3, July 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.874 KB) | DOI: 10.32771/inajog.v4i3.432

Abstract

Objective: Pregnancy in advanced maternal age (AMA) was classified as high risk. The study aims to provide a better description of pregnancy outcome in AMA. Method: The cross sectional study was to review the demography, medical and obstetrics problems, mode of delivery, maternal and fetal outcome in Tangerang General Hospital as a referral center in Banten. The data were taken from medical records of 35-year-old and above women age who delivered on the period of January to December 2014. Result: The total number of delivery and live birth was 6,107 and 5,926 respectively, including 1,548 (25.36%) pregnancies in AMA. The prevalence of grandmultiparities was 11.4%. The average education level was mostly elementary. The prevalence of hypertension in pregnancy was 34.6%. There was increasing trend of miscarriages from 10.8% in 35-40-year-old group to 25% in above 45- year-old group. Pregnancy complications were higher consisting of 3.2% multifetal, 16.6% malpresentation, and 7.1% placenta previa. Cesarean section rate was 33.6%. Maternal near-missed cases were 56 of 1000 and the maternal mortality rate (MMR) was 932 of 100,000 live births. The prevalence of stillbirth and perinatal mortality were 5.3% and 12.9%; respectively. Conclusion: Adverse maternal and fetal outcome were higher in AMA as it takes special attention and multidiscipline-approached care started from preconception, antenatal, preparation of delivery, and also postpartum care. Keywords: advanced maternal age (AMA), fetal outcome, maternal outcome, pregnancy
Lower Ferrum, Selenium, and Cadmium; Higher Chromium and Lead Levels in Preeclampsia Patients’ Erythrocyte: A Cross-Sectional Study Prayudhana, Sandhy; Prasmusinto, Damar; Wibowo, Noroyono; Irwinda, Rima; Purwosunu, Yuditiya; Saroyo, Yudianto Budi
The Indonesian Biomedical Journal Vol 17, No 1 (2025)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v17i1.3257

Abstract

BACKGROUND: Oxidative stress and trace elements in erythrocytes are linked to impaired nitric oxide that can lead to endothelial dysfunction in preeclampsia patients. The morphology of erythrocytes could also be affected by oxidative stress and trace elements. While the relationships between erythrocyte index, superoxide dismutase (SOD) activity, and oxidative stress in preeclampsia have been well established, less attention has been given to the erythrocyte trace elements and their role in disease progression. This study was performed to examine the erythrocyte trace element profile in women with preeclampsia, comparing it with controls. Additionally, it will explore the correlations between erythrocyte trace element levels, the erythrocyte index, and SOD activity.METHODS: A cross-sectional study was conducted involving 40 pregnant women consisting of those with severe preeclampsia and normotensive. Erythrocytes was isolated from blood samples, and analysis of erythrocyte SOD activity and trace elements were performed using the enzyme linked immunosorbent assay (ELISA) and inductively coupled plasma mass spectrometry (ICP-MS), respectively.RESULTS: Among 15 examined erythrocyte trace elements, the levels of ferrum (Fe), selenium (Se), and cadmium (Cd) were significantly lower, meanwhile, the levels of chromium (Cr) and lead (Pb) were significantly higher in preeclampsia subjects. Additionally, preeclampsia subjects exhibited smaller erythrocyte sizes compared to the normotensive subjects. The erythrocyte SOD activity was significantly elevated in the preeclampsia subjects than the normotensive subjects.CONCLUSION: Erythrocyte trace element levels of Fe, Se, Cd, Cr, and Pb were significantly altered in preeclampsia compared to normotensive controls. These findings suggest that these trace elements may serve as potential predictors for preeclampsia.KEYWORDS: preeclampsia, trace elements, antioxidant, oxidative stress, superoxide dismutase, erythrocyte index
Co-Authors Damar Prasmusinto Ferry, Ferry Ferry, Ferry Noroyono Wibowo Purwosunu, Yuditiya Rima Irwinda, Rima Saroyo, Yudianto Budi Sianty Dewi Toynbee, Eddy Wachyu Hadisaputra