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Boed Sinai Singadipoera
Department of Child Health, Universitas Padjadjaran Medical School/Dr. Hasan Sadikin Hospital, Bandung, West Java
Health Professions Medicine & Pharmacology

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Renal tubular function of the child with thalassemia major who received repeated blood trransfusion Dany Hilmanto; Boed Sinai Singadipoera; Ponpon Ijradinata
Paediatrica Indonesiana Vol 39 No 7-8 (1999): July - August 1999
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (535.391 KB) | DOI: 10.14238/pi39.7-8.1999.193-200

Abstract

A descriptive study was done from December 2 , 1994 to January 5,1995, at the Department of Child Health of Hasan Sadikin General Hospital Bandung. A total of 50 thalassemia major patients who bad received 5,000 ml or more of blood transfusions and never received desfenioxamine underwent a renal tubular function test using a radionuclide technique (l-123 Hippuran) to determine the effective renalplasmft flow (ERPF). The subjects were div:ided into two groups according to the amount of transfusion. Group A who received a total of 5,000 to 10,000 mL of blood transfusion consisted of 23 children (11 boys and 12 girls); group B, those who received a total of 10,000 ml or more of blood transfusion, consisted of 27 children (14 boys and 13 girls). The total average of blood transfused for group A and B were 7563.91 (1780.59) and 20,665.93 (6632.39) rnl, respectively. The ERPF of all subjects were below the normal standard. The average value of ERPF of group A and B were 205.78 (62 .08) and 214.09 (59.44) ml/minute/1.73 m2, respectively. The correlation between the total amount of blood transfusion and ERPF of the subjects was not significant (Group A had r=O.l63, p=0.458; Group B had r=0.084, p=0 .934).
Co-Authors Dany Hilmanto Ponpon Ijradinata