Purnama Wati S. P.
Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta

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Graves' Disease and Diabetes Mellitus M. Suttan Assin; Jusuf Rukman; Jose R. L. Batubara; Purnama Wati S. P.
Paediatrica Indonesiana Vol 32 No 11-12 (1992): November - December 1992
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.322 KB) | DOI: 10.14238/pi32.11-12.1992.327-31

Abstract

Thyroid hormones play an important role in the metabolic propesses. Its disturbances will involve several organs, consequently. A 5 year old girl with Graves' diseases, after several weeks of treatment with propylthiouracil (PTV), developed thyrotoxicosis crisis and diabetes mellitus with ketoacidosis; a condition which is usually fatal. Treatment toward the hyperthyroid state overcome the diabetic stage, eventually. This report is an example of an endocrinological interaction in a hyperthyroid patient. Therefore, the diabetogenic effect of hyperthyroxinemia should not be overlooked.