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All Journal Paediatrica Indonesiana Detector: Jurnal Inovasi Riset Ilmu Kesehatan
Eko Kristanto Kunta Adjie
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Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Plasma NT-proBNP and pulmonary to systemic blood flow ratio in congenital heart defects with left-to-right shunts Eko Kristanto Kunta Adjie; Ni Putu Veny Kartika Yantie; Made Gede Dwi Lingga Utama; Eka Gunawijaya; Ketut Ariawati; Ida Bagus Subanada; Anak Agung Ngurah Ketut Putra Widnyana
Paediatrica Indonesiana Vol 60 No 6 (2020): November 2020
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi60.6.2020.310-5

Abstract

Background Cardiac left-to-right shunts changes to the pulmonary-to-systemic blood flow ratio (Qp/Qs ratio). This ratio can be used to monitor the hemodynamics of the heart. Left-to right-shunts cause the release of amino terminal proB-ty natriuretic peptide (NT-proBNP) that can be utilized as a specific marker for the presence of heart failure in children with congenital heart defects (CHDs). Early intervention such as defect closure in CHD is important to prevent heart failure. Objective To assess for a correlation between the level of NT pro-BNP and Qp/Qs ratio in CHD patients with left-to-right shunts. Methods This cross-sectional, analytical study was conducted in 32 children who underwent cardiac catheterization at Sanglah General Hospital, Denpasar, Bali, and were recruited by consecutive sampling. NT-proBNP levels were measured by ELISA with a two-step sandwich assay system; Qp/Qs ratio using Fick rules. Statistical analyses included Shapiro-Wilk test, descriptive analysis for subject characteristics, and Pearson’s correlation analysis. A P value of <0.05 was considered to be statistically significant. Age and defect size were analyzed as confounding factors by partial correlation test. Results The correlation value between NT-proBNP and Qp/Qs ratio was r=0.384 (P<0.05), after controlling for age and defect size as cofounding factors. Conclusion There is a weak positive correlation between NT-proBNP levels and pulmonary-to-systemic blood flow ratio in patients with left-to-right shunt, after controlling for age and defect size as confounding factors.
Aktifitas Fisik dan Status Gizi Siswa Kelas VIII dan IX di MTS Negeri 1 Murung Dian Hafsari Fitri; Eko Kristanto Kunta Adjie
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 1 No. 3 (2023): Agustus : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (785.468 KB) | DOI: 10.55606/detector.v1i3.2065

Abstract

The problem of malnutrition status is a serious concern in children and teenagers because it affects their growth and development period. Nutritional status really affects physical development. Nutritional status is influenced by eating habits and daily physical activities. Lack of physical activity is increasing the chance of being overweight or obese. The aims of this research were to examine the correlation between physical activity and nutritional status of the students in VIII and IX grades at MTS Negeri 1 Murung. This research was conducted by using the observational method and cross sectional design. The research was conducted from July to December 2022 at MTS Negeri 1 Murung, in Central Borneo province. The sample of the research was 166 students. The results of the research showed that the majority of the students were in the IX grade (63.9%). Based on the age, the majority of students were 15 years old (63.9%). Based on gender, the majority of the students were females (68.1%). The physical activity of the students in VIII and IX grades at MTS Negeri 1 Murung was in the moderate category with 111 students (66.9%). The majority of nutritional status of the students in VIII and IX grades at MTS Negeri 1 Murung was in the normal category with 88 students (53%). There was a strong correlation between the physical activity and nutritional status of the students in the VIII and IX grades at MTS Negeri 1 Murung, the value of it was p=0.003.
Co-Authors Anak Agung Ngurah Ketut Putra Widnyana Dian Hafsari Fitri Eka Gunawijaya Ida Bagus Subanada Ketut Ariawati Made Gede Dwi Lingga Utama NP Veny Kartika Yantie