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All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
B Rusli
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

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POLA KUMAN BERDASARKAN SPESIMEN DAN SENSITIVITAS TERHADAP ANTIMIKROBA Rostina Rostina; B Rusli; M Arief; Hardjoeno Hardjoeno
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.890

Abstract

High prevalence of infectious diseases in Indonesia lead to the use of uncontrollable anti microbial treatment with less concern todrug resistance, marked with fewer requests for sensitivity testing. This leads to irrational anti microbial treatment and increasing drugresistance. With unsupported condition for using a sensitivity test prior to anti microbial treatment, a common guide for choosing ananti microbial agent for infection of specific organ system is needed. A descriptive study of retrospectively collected data of sensitivity testresults was done on 841 spesimens from sources of infected organs in Wahidin Sudirohusodo Hospital of Makassar during 2005–2006periods. Objectives of this study are to know the microbial pattern of specific organ infection (represented by microbes of the specimens),antimicrobial sensitivity pattern of the microorganisms, and whether there is shifting of the pattern within a 1 year period. Shiftingof microbial patterns during 2005–2006 period was found. Klebsiella aeroginosa, Enterobacter agglomerans, Alkaligenes faecalis andEscherichia coli were the most frequent micro organisms found from spesimens examined. Most of antimicrobial drugs commonlyused were found effective to most of micro organisms, while amikacin, cefepime, gentamycin, sulbactam, tobramycin, vancomycin andmeropene were still sensitive enough to the majority of the infectious agents.
NILAI TROPONIN T (cTnT) PENDERITA SINDROM KORONER AKUT (SKA) R A Nawawi; Fitriani Fitriani; B Rusli; Hardjoeno Hardjoeno
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 12, No 3 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v12i3.872

Abstract

Acute Coronary Syndrome (ACS) is an emergency cardiac condition manifested by chest pain or other symptoms as the result ofischemic myocardium. Myocardial damage can be detected by Creatine Kinase MB (CK-MB), Lactate Dehydrogenase (LDH) and cTnTtests. CTnT can be used as criteria of therapy determination. The combination of CK-MB and cTnT are the most effective tests if theearly myocardium damage is unknown, to evaluate cTnT, CK-MB, and LDH values in patients with Acute Coronary Syndrome (ACS) atWahidin Sudirohusodo Hospital, Makassar. Secondary data were collected from the medical records (from March to July 2005 period)at Wahidin Sudirohusodo Hospital, Makassar. Chi-square and Spearman correlation were carried out to analyze the collected data. Theinvestigators found 90 patients with ACS consisted of 57 males (63.33%) and 33 females (36.67%). The highest cTnT Value of 0.1 to2.0 ng/ml was found in 39 patients (43.33%), 30 females (52.63%). Significant correlation showed by Chi-square test between IMAEKG and cTnT values (p < 0.05). Spearman correlation test demonstrated significant correlation between cTnT value and CK-MB andLDH (p = 0.001). Most cTnT values were found in the male patients with ACS, aged 60 to 69 years and significantly correlated withIMA’s ECG, CK-MB and LDH.
Co-Authors Fitriani Fitriani Hardjoeno Hardjoeno M Arief R A Nawawi Rostina Rostina