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Windarwati Windarwati
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

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KADAR CTX PEREMPUAN OSTEOPOROSIS LEBIH TINGGI DARIPADA PEREMPUAN NORMAL DAN OSTEOPENIA Ira Puspitawati; Windarwati Windarwati; Usi Sukorini; Erlina Erlina; Pratiwi Herowati; Arlan Prabowo; Riswan Hadi Kusuma
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 19, No 3 (2013)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v19i3.413

Abstract

Regarding to the ageing population in most countries, degenerative and metabolism diseases included osteoporosis are becoming increasingly and need special attention in all country especially in the developing country such as Indonesia. Current WHO recommendation of using a gold standard for establishing osteoporosis is by Dual X-Ray Absorptiometry (DEXA), but it is expensive and not yet widely available. There are some alternatives of biochemical markers that can reflect the bone turn over. One of them is Cterminal cross-linking telopeptide of type I collagen (CTX) or betacrosslabs, a marker of bone resorbtion. There are still limited studies on correlation of CTX and osteoporosis in peri menopausal and post menopausal women. The aim of this study is to know whether there are any differences of CTX level among peri menopausal and post menopausal women with different bone density. This research was a cross sectional study and aimed to know whether there is any correlation between CTX level and Bone Mineral Density Score measured with DEXA. The study was conducted in June-August 2010. The included subjects were women with age more than 45 years old, without apparent history of neoplasm, impaired renal function, bone metabolic diseases, and not currently pregnant. CTX level were measured using immunochemiluminescent. Their data were analysed using One Way ANOVA. This study showed that there are differences of CTX levels among women with osteoporosis, osteopenia, and normal (0.633±0.25 ng/mL vs 0.514±0.21 ng/mL vs 0.406±0.21 ng/mL p=0.02). Osteoporosis women have higher CTX level compared to Osteopenia and Normal women.
RESISTENSI Mycobacterium Tuberculosis TERHADAP OBAT ANTI TUBERKULOSIS A. Nikmawati; Windarwati Windarwati; Hardjoeno Hardjoeno
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 12, No 2 (2005)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v12i2.843

Abstract

Patients infected with resistant Mycobacterium tuberculosis strain will be very difficult to cure by standard treatment. To evaluatethe drug resistance of Mycobacterium tuberculosis. A Cross sectional study was performed from January until July 2005. Samples wereobtained from sputum of the suspect tuberculosis. All samples were cultured in Lowenstein-Jensen Media and followed by sensitivity testaccording to resistance ratio method. Of 236 samples, there were 30% positive cultures. The percentage of mono-resistance to Isoniazidwas 70%, to Rifampicin 64.3%, to Ethambutol 62.8% and Streptomycin 64.3%. The percentage of Multi Drug Resistant Tuberculosis(MDR-TB) was 20–40% and the percentage of poly-resistant (Ethambutol and Streptomycin) was 47.1%. The percentage of suspecttuberculosis with positive culture was 30%. There were also found high percentage of mono-resistant, poly-resistant and MDR-TB.
POLA DAN SENSITIVITAS KUMAN DI PENDERITA INFEKSI SALURAN KEMIH Samirah Samirah; Darwati Darwati; Windarwati Windarwati; Hardjoeno Hardjoeno
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 12, No 3 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v12i3.869

Abstract

The bacterial and sensitivity pattern towards antimicrobials on urinary tract infections (UTI) patients are very important to beknown by clinicians to get a successful treatment. The bacterial and sensitivity pattern towards antimicrobials will be changed in differentplace and time, so that those should be analyzed routinely. To evaluate the bacterial and antimicrobials resistance pattern on urinarytract infections patients. A retrospective study on 220 urinary samples in January until December 2004 at Clinical Microbiology subunit of Dr.Wahidin Sudirohusodo hospital . Of 99 samples of UTI, Prevalence of UTI in woman (54.5%) were higher than man (45.5%).Most of sample (28 samples) were found in 0 to 15 years group. The most bacteries in urine were Escherichia coli (39.4%) and Klebsiella(26.3%). Amikacin was sensitive to all bacteries, while amoxicilin and ampicilin were resistance. Prevalence of UTI in women werehigher than in men. Incidens of UTI was highest in children group. The most bacteries in urine samples were Escherichia coli. Amikacinwas sensitive to all bacteries, while Amoxicilin and Ampicilin were resistance.
Co-Authors A. Nikmawati Arlan Prabowo Darwati, Darwati Erlina Erlina Hardjoeno Hardjoeno Ira Puspitawati Pratiwi Herowati Riswan Hadi Kusuma Samirah Samirah Usi Sukorini