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All Journal Berkala Penelitian Hayati
Bambang Soekardjo
Fakultas Farmasi, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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AKTIVITAS ANTIBAKTERI NBENZOILAMOKSISILIN DAN N34DIKLOROBENZOILAMOKSISILIN TERHADAP Staphylococcus ATCC 25923 DAN Escherichia coli ATCC 35218 Harry Santosa; Bambang Soekardjo; Ami Soewandi J S
JURNAL PENELITIAN BIOLOGI BERKALA PENELITIAN HAYATI Vol 5 No 2 (2000): June 2000
Publisher : The East Java Biological Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23869/470

Abstract

N-Benzolamoxicillin and N-3,4-dichlorobenzolamoxicillin were synthesized from amoxicillin by acylation with benzoylchloride and 3,4-dichlorobenzoylchloride respectively. Structure characterization of the amoxicillin derivative compounds were done by UV, IR and 1H-NMR spectroscopy. Both derivative compound has antibacterial antivity against Staphylococcus aureus and Escherichia coli. The activity of N-3,4-dichlorobenzolamoxicillin is more active than N-Benzolamoxicillin.
Co-Authors Ami Soewandi J S Harry Santosa