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FORMULASI GRANUL INSTAN EKSTRAK HERBA PEGAGAN (Centella asiatica) DAN ANALISIS ASIATIKOSIDA - Prasetyorini; Bina Lohitasari; Ahmad Amirudin
EKOLOGIA Vol 12, No 1 (2012): JURNAL ILMIAH ILMU DASAR DAN LINGKUNGAN HIDUP
Publisher : Universitas Pakuan

The research was conducted in the month from February until April 2011 in the laboratory of Pharmacy Faculty of Mathematics and Natural Sciences, University Pakuan. The research objective is to make a health drink formulation of herbs gotu kola extract and determine the form of instant granules asiatikosida content. Herb gotu kola is used in this study is the collection BALITRO. In this study of instant granules prepared by wet granulation method and made three formulas are: FI (formula without essence), F II (formula with caramel essence, and F III (formula with mango essence.) Asiatikosida analysis performed on dry ekstrakt by TLC method the scanner. the results showed all formulas have the instant granule flow rate and good Sagat compressibility, organoleptic tests (smell and color), which are the F III, asiotikosida content showed a decrease during processing. Gynecology asiatikosida ekstrakt dry is 1.75% (4.375 mg asiatikosida) , instant granules FI of 0.46% (0.052 mg asiatikosida), F II by 0.68% (0.072 mg asiatikosida), and F III amounting to 0.48% (0.056 mg asiatikosida). Rf value on testing asiatikosida in extracts obtained 0.81 with a standard 0.80. Rf value on testing for FI 0.28 instant granules; FII 0.28, and F III 0.29, the standard used for Rf value of 0.28Kata kunci : ekstrak herba pegagan, granul instan, asiatikosida

AKTIFITAS BERBAGAI SEDIAAN BUAH SIRSAK (Annona muricata Linn) DALAM PENURUNAN KADAR ASAM URAT TIKUS PUTIH Sprague-Dawley - Prasetyorini; - Moerfiah; Sri Wardatun; - Affandi
EKOLOGIA Vol 14, No 2 (2014): JURNAL ILMIAH ILMU DASAR DAN LINGKUNGAN HIDUP
Publisher : Universitas Pakuan

Research potential of juice, extract ethanol, ethyl acetate extracts with different doses of soursop fruit as down as the asamurat has been performed. The treatment given these supplies juice with doses of 930 mg, 1870 2810 mg and mg: 96% ethanol extract with a dose of 26.79 g/100 ml, 53.58 g/100 ml and 80.37 g/100 ml; and extract with ethyl acetate dose 2.58 g/100 ml, 5.16 g/100 ml and 7.74 g/100 ml. The making of extracts is done with methods of maceration of fruit juice, and squeeze the flesh of the fruit directly with Batiste. The results of qualitative testing all positive preparations contain a flavanoid, alkaloids, tannins, saponins and polyphenols. The content of polyphenols 100 g ingredients for fruit juice, extract 96% ethanol and ethyl acetate extracts of consecutive 0.473 g SAG: SAG 0.324 g; and 0.194 mg SAG. Vitamin C 100 g of ingredients for fruit juice, extract 96% ethanol and ethyl acetate extracts of consecutive 38.24 mg; 30.56 mg; 35.66 mg. for 100 g K Content material to juice, extract the ethanol 96% ethyl acetate extracts and a row of 0.39 g; 0.26 g; 0.22 g. Content of 100 g each Na ingredients for fruit juice, extract the ethanol 96% ethyl acetate extracts and a row of 0.0269 g; 0.0416 g; 0.0436 g. The results showed the treatment given the very real effect of lowering uric acid levels of rats, a third dose of juice lowers blood uric acid levels up to 40%, 96% ethanol extract Dosage dose 53.58 g/100 ml and 80.37 g/100mlserta ethyl acetate extract dosage 7.74 g/100 ml can also lower blood uric acid levels exceed the positive control.Key words: Uric acid, fruit juice, ethanol and ethyl acetate extract fruit soursop (Annona muricata Linn),

PERBEDAAN STRUKTUR ANATOMI TUMBUHAN PENGHASIL GAHARU Aquilaria spp. DAN Gyrinops versteegii - Widoyanti; - Prasetyorini; - Ismanto
EKOLOGIA Vol 17, No 1 (2017): JURNAL ILMIAH ILMU DASAR DAN LINGKUNGAN HIDUP
Publisher : Universitas Pakuan

The cross and longitudinal section anatomical structure of Aquilaria malaccensis, A. beccariana, A. decipiens, A. microcarpa and Gyrinops versteegii has been studied using paraffin method following Sass (1951) as well as paraderm section and maceration as described in Cutler (1978). The results showed that there were differences in the type of crystal, the number of neighboring cells, the epidermal cells form on upper and lower leaf surfaces and in stomatal index. Further more the differences were also appeared at fingers pith and niche forms. The stomatal index percentage was different significantly with the highest percentage found in A. decipiens 8.47%, followed by A. beccariana 6.73%; A. microcarpa 3.84%; A. malaccensis 3.49% and the lowest percentage was G. versteegiiie 1.60%.Key words: Aquilaria spp., Gyrinops versteegii, plant anatomy, stomatal index

ANALISIS KANDUNGAN TIMBAL, TEMBAGA DAN ARSEN PADA DAUN KANGKUNG (Ipomoea aquatica) YANG DIJUAL DI TEMPAT YANG BERBEDA DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM - Prasetyorini; Sri Wardatun
EKOLOGIA Vol 11, No 2 (2011): JURNAL ILMIAH ILMU DASAR DAN LINGKUNGAN HIDUP
Publisher : Universitas Pakuan

Kangkung merupakan sumber gizi yang murah harganya dan mudah untuk mendapatkannya. Kangkung yang ditanam dan disiram dengan air yang tercemar kemungkinan besar akan mengandung logam pencemar tersebut. Penelitian ini menganalisis kandungan logam pencemar pada kangkung yang dijual di pasaran dengan metode spektrofotometri serapan atom (AAS). Hasil menunjukkan bahwa kangkung yang dijual di pasaran mengandung logam timbal, arsen dan tembaga dengan kadar di bawah kisaran maksimum yang diijinkan dalam pangan. Kata kunci : Kangkung, logam berat, AAS

PENERAPAN TEKNOLOGI NANOPARTIKEL PROPOLIS TRIGONA SPP ASAL BOGOR SEBAGAI ANTIBAKTERI ESCHERICHIA COLI SECARA IN-VITRO - Prasetyorini; AE. Zainal Hasan; Rofiqoh Siregar
EKOLOGIA Vol 11, No 1 (2011): JURNAL ILMIAH ILMU DASAR DAN LINGKUNGAN HIDUP
Publisher : Universitas Pakuan

Penelitian penerapan nanopartikel propolis Trigona spp asal Bogor sebagai antibakteri Escherichia coli secara in-vitro bertujuan membuat sediaan nanopartikel dari propolis Trigona spp asal Bogor (nanopropolis). Pembuatan nanopropolis dilakukan dengan cara penyalutan dan homogenizer pada kecepatan 22.000 rpm selama satu jam. Dalam penelitian ini dilakukan melalui empat tahap, yaitu tahap ekstraksi raw propolis Trigona spp, tahap pembuatan sediaan nanopropolis, tahap melakukan uji aktivitas nanopropolis sebagai antibakteri dan menentukan konsentrasi hambat tumbuh minimum (KHTM) nanopropolis terhadap bakteri Escherichia coli. Hasil penelitian menunjukkan bahwa Propolis Trigona spp asal Bogor dapat dibuat nanopartikel dengan ukuran partikel mencapai 192 273 nm. Ukuran partikel nanopropolis dideteksi menggunakan Scanning Electron Microscopy. Hasil uji aktivitas antibakteri menunjukkan bahwa pada konsentrasi 0,02%-10% nanopropolis aktif sebagai antibakteri terhadap bakteri Escherichia coli. Konsentrasi hambat tumbuh minimum nanopropolis berada di bawah konsentrasi 0,02%. Ketika dibandingkan dengan sediaan tanpa teknologi nano (propolis biasa), pada kondisi konsentrasi sama nanopropolis lebih efektif daripada propolis biasa karena zona hambat yang dihasilkan lebih besar.Kata kunci : Trigona spp, propolis, dan teknologi nano

FORMULASI DAN UJI STABILITAS GRANUL EFERVESEN SARI BUAH SIRSAK (Annona muricata L.) - Prasetyorini; Ike Yulia Wiendarlina; Murni Tiradisuci
EKOLOGIA Vol 15, No 2 (2015): JURNAL ILMIAH ILMU DASAR DAN LINGKUNGAN HIDUP
Publisher : Universitas Pakuan

This event will be based on research by the large number of reports on the benefits of soursop for various diseases especially antihipertensi and antihiperuresemia. Forms need to be developed so that a more practical preparations and ketersediannya continuous, one of which is in the form of effervescen granule juice. This research aims to find out whether the soursop fruit juice can be a formulation in granule material of efervesen who meet the requirements of quality, standards and terms of efervesen granule and making it acceptable in society. In the study of fruit juice made with the soursop fruit flesh filter using Batiste, juice drained using Freezedryer with the addition of maltodekstrin 20%. The powder is then made 3 fruit formula granule effervesent with the difference of acid-catalyzed and the manufacturing process is done by the method of smelting using alcohol 70% without binder. Test results show the BSLT fruit pollen have toxic effects against larvae of shrimp Artemiasalina Leach with LC50 108.914 ppm. The results of the evaluation of the third shows the formula for granule corner quietly and solubility are eligible, cohesive, and the granule flow values test froth above 70%, the test results of licentious formula2 has the most preferred taste. Stability test for efervesen granule 8 weeks the most stable at a temperature of 15 C containing Sodium ion levels 3, 97g/100 ggranul, potassium of 0, 24g/100 ggranul, 2, 19mg SAG polyphenols/ggranul and vitamins C51, 91mg/100ggranul.Key words : granul, efervesen, stabilitas, sirsak

FORMULASI GRANUL INSTAN EKSTRAK HERBA PEGAGAN (Centella asiatica) DAN ANALISIS ASIATIKOSIDA - Prasetyorini; Bina Lohitasari; Ahmad Amirudin
Ekologia: Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Vol 12, No 1 (2012): Ekologia : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/ekol.v12i1.252

The research was conducted in the month from February until April 2011 in the laboratory of Pharmacy Faculty of Mathematics and Natural Sciences, University Pakuan. The research objective is to make a health drink formulation of herbs gotu kola extract and determine the form of instant granules asiatikosida content. Herb gotu kola is used in this study is the collection BALITRO. In this study of instant granules prepared by wet granulation method and made three formulas are: FI (formula without essence), F II (formula with caramel essence, and F III (formula with mango essence.) Asiatikosida analysis performed on dry ekstrakt by TLC method the scanner. the results showed all formulas have the instant granule flow rate and good Sagat compressibility, organoleptic tests (smell and color), which are the F III, asiotikosida content showed a decrease during processing. Gynecology asiatikosida ekstrakt dry is 1.75% (4.375 mg asiatikosida) , instant granules FI of 0.46% (0.052 mg asiatikosida), F II by 0.68% (0.072 mg asiatikosida), and F III amounting to 0.48% (0.056 mg asiatikosida). Rf value on testing asiatikosida in extracts obtained 0.81 with a standard 0.80. Rf value on testing for FI 0.28 instant granules; FII 0.28, and F III 0.29, the standard used for Rf value of 0.28Â Kata kunci :Â Â ekstrak herba pegagan, granul instan, asiatikosida

AKTIFITAS BERBAGAI SEDIAAN BUAH SIRSAK (Annona muricata Linn) DALAM PENURUNAN KADAR ASAM URAT TIKUS PUTIH Sprague-Dawley - Prasetyorini; - Moerfiah; Sri Wardatun; - Affandi
Ekologia: Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Vol 14, No 2 (2014): Ekologia : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/ekol.v14i2.215

Research potential of juice, extract ethanol, ethyl acetate extracts with different doses of soursop fruit as down as the asamurat has been performed. The treatment given these supplies juice with doses of 930 mg, 1870 2810 mg and mg: 96% ethanol extract with a dose of 26.79 g/100 ml, 53.58 g/100 ml and 80.37 g/100 ml; and extract with ethyl acetate dose 2.58 g/100 ml, 5.16 g/100 ml and 7.74 g/100 ml. The making of extracts is done with methods of maceration of fruit juice, and squeeze the flesh of the fruit directly with Batiste. The results of qualitative testing all positive preparations contain a flavanoid, alkaloids, tannins, saponins and polyphenols. The content of polyphenols Â 100 g ingredients for fruit juice, extract 96% ethanol and ethyl acetate extracts of consecutive 0.473 g SAG: SAG 0.324 g; and 0.194 mg SAG. Vitamin C 100 g of ingredients for fruit juice, extract 96% ethanol and ethyl acetate extracts of consecutive 38.24 mg; 30.56 mg; 35.66 mg. for 100 g K Content material to juice, extract the ethanol 96% ethyl acetate extracts and a row of 0.39 g; 0.26 g; 0.22 g. Content of 100 g each Na ingredients for fruit juice, extract the ethanol 96% ethyl acetate extracts and a row of 0.0269 g; 0.0416 g; 0.0436 g. The results showed the treatment given the very real effect of lowering uric acid levels of rats, a third dose of juice lowers blood uric acid levels up to 40%, 96% ethanol extract Dosage dose 53.58 g/100 ml and 80.37 g/100mlserta ethyl acetate extract dosage 7.74 g/100 ml can also lower blood uric acid levels exceed the positive control.Â Key words:Â Â Uric acid, fruit juice, ethanol and ethyl acetate extract fruit soursop (Annona muricata Linn),

ANALISIS KANDUNGAN TIMBAL, TEMBAGA DAN ARSEN PADA DAUN KANGKUNG (Ipomoea aquatica) YANG DIJUAL DI TEMPAT YANG BERBEDA DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM - Prasetyorini; Sri Wardatun
Ekologia: Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Vol 11, No 2 (2011): Ekologia : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/ekol.v11i2.258

Kangkung merupakan sumber gizi yang murah harganya dan mudah untuk mendapatkannya. Kangkung yang ditanam dan disiram dengan air yang tercemar kemungkinan besar akan mengandung logam pencemar tersebut. Penelitian ini menganalisis kandungan logam pencemar pada kangkung yang dijual di pasaran dengan metode spektrofotometri serapan atom (AAS). Hasil menunjukkan bahwa kangkung yang dijual di pasaran mengandung logam timbal, arsen dan tembaga dengan kadarÂ di bawah kisaran maksimumÂ yang diijinkan dalam pangan. Â Kata kunci : Kangkung, logam berat, AAS

PENERAPAN TEKNOLOGI NANOPARTIKEL PROPOLIS TRIGONA SPP ASAL BOGOR SEBAGAI ANTIBAKTERI ESCHERICHIA COLI SECARA IN-VITRO - Prasetyorini; AE. Zainal Hasan; Rofiqoh Siregar
Ekologia: Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Vol 11, No 1 (2011): Ekologia : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/ekol.v11i1.237

Penelitian penerapan nanopartikel propolis Trigona spp asal Bogor sebagai antibakteri Escherichia coli secara in-vitro bertujuan membuat sediaan nanopartikel dari propolis Trigona spp asal Bogor (nanopropolis). Pembuatan nanopropolis dilakukan dengan cara penyalutan dan homogenizer pada kecepatan 22.000 rpm selama satu jam. Dalam penelitian ini dilakukan melalui empat tahap, yaitu tahap ekstraksi raw propolis Trigona spp, tahap pembuatan sediaan nanopropolis, tahap melakukan uji aktivitas nanopropolis sebagai antibakteri dan menentukan konsentrasi hambat tumbuh minimum (KHTM) nanopropolis terhadap bakteri Escherichia coli. Hasil penelitian menunjukkan bahwa Propolis Trigona spp asal Bogor dapat dibuat nanopartikel dengan ukuran partikel mencapai 192 â€“ 273 nm. Ukuran partikel nanopropolis dideteksi menggunakan Scanning Electron Microscopy. Hasil uji aktivitas antibakteri menunjukkan bahwa pada konsentrasi 0,02%-10% nanopropolis aktif sebagai antibakteri terhadap bakteri Escherichia coli.Â Konsentrasi hambat tumbuh minimumÂ nanopropolis berada di bawah konsentrasi 0,02%. Ketika dibandingkan dengan sediaan tanpa teknologi nano (propolis biasa), pada kondisi konsentrasi sama nanopropolis lebih efektif daripada propolis biasa karena zona hambat yang dihasilkan lebih besar.Â Kata kunciÂ : Â Trigona spp, propolis, dan teknologi nano

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