Garuda - Garba Rujukan Digital

The Level of Ca125 in Preand Postoperative of Endometriosis Asriyanti Amsir; Andi M Tahir; Nusratuddin Abdullah
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No.3, July 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To determine the Ca-125 level in pre- and post-operative of endometriosis and its correlation to endometriosis stage and severity of dysmenorrhea. Method: This was a cross-sectional study design conducted at Dr. Wahidin Sudirohusodo dan some affiliated hospitals. We took the patients undergoing laparoscopy or laparotomy consecutively. Result: The mean value of preoperative Ca-125 level in stage I-II was 21.53 (SD 12.64) IU/ml vs 72.52 (SD 8.52) IU/ml in stage III-IV. The mean value of postoperative Ca-125 level was 14.82 (SD 10.00) IU/ml (stage I-II) vs 61.03 (SD 8.43) IU/ml (stage III-IV); they were significantly different (p

AntiMÃ¼llerian Hormone Level in Laparoscopic Cystectomy Edwin Budipramana; Nusratuddin Abdullah; Telly Tessy
Indonesian Journal of Obstetrics and Gynecology Volume 4, No. 4, October 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To evaluate the impact of laparoscopic cystectomy using cautery and suturing technique on the ovarian reserve represented by the level of Anti-MÃ¼llerian Hormone (AMH) serum. Method: This used prospective cohort study design conducted in Dr. Wahidin Sudirohusodo Hospital, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Hasanuddin, Makassar, from November 2014 to October 2015. We got total samples of 60 subjects divided into cautery and suturing group. Anti-Mullerian hormone serum test was examined on all subjects pre and post laparoscopic cystectomy. Result: The result indicated a significant decrease of AMH level undergoing laparoscopic cystectomy both cautery and suturing technique; whereas, more dominant results were showed in the cautery group (p0.05). Conclusion: The decline in the number of ovarian reserve as described by the reduction of AMH level occurs significantly in both cauterization and suturing technique, which are more dominant reduction in the cauterization group. [Indones J Obstet Gynecol 2016; 4-4: 203-207] Keywords: Anti-MÃ¼llerian Hormone, laparoscopic cystectomy, ovarian reserve

Anti MÃ¼llerian Hormone (AMH) Level as Ovarian Reserve Marker before and after Cystectomy Laparotomy Rosdiana Sahabuddin; Nusratuddin Abdullah; IMS Murah Manoe
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 1, January 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the comparison of the Anti-Mullerian Hormone (AMH) as the ovarian reserve marker before and after cystectomy. Methods: This study used prospective cohort design which included all women with the ovarian cyst who underwent cystectomy laparotomy. The subjects were examined AMH level before and after the procedure. Data were analyzed using one- way Anova, T- paired test, and T-independent test with p value

The Role of Matrix Metalloproteinase9 (MMP9) in Endometriosis: Peran Matriks MetalloproteinaseÂ9 (MMPÂ9) pada Endometriosi Amalia Amalia; Nusratuddin Abdullah; Umar Malinta
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the role of MMP-9 expression in endometriosis. Methods: The study was conducted from October 2015 to March 2016, an observational study with cross-sectional design. Samples are all endometriosis patients who underwent laparoscopic surgery in Dr. Wahidin Sudirohusodo Hospital and several other hospitals in Makassar. Samples were stored and fixed in the Grand Medika Histopathology Laboratory Makassar for examination the expression of MMP-9 using immunohistochemical methods. Conducted an analysis of 50 samples, of which 11 samples of stage II, 21 stage III samples, and 18 samples of stage IV. The data obtained and analyzed statistically using Mann Whitney and Chi Square test with a significance level of p <0.05. Results: The results reported rankings mean the expression of MMP-9 in stage I-II = 16.68, stage III-IV 27.99 (p = 0.013). There were differences in the expression of MMP-9 based on the stage. Stage I-II endometriosis had a more positive 2 expression of MMP-9 (45.5%), stage III-IV endometriosis have more positive 3 expression of MMP-9 (59.0%). The results of chi square test (p = 0.043). Conclusion: Higher expression of MMP-9 is significantly associated with higher degree of endometriosis. Keywords: matrix metalloproteinase-9, stages of endometriosis

Estradiol Level and Psychosocial Stress in Perimenopausal Women: Kadar Estradiol dan Stres Psikososial pada Perempuan Perimenopause Lucia L Levita; Hadiprodjo Hadiprodjo; Nusratuddin Abdullah; Nugraha U Pelupessy
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 2 April 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective : To determine the relationship between estradiol levels and psychosocial stress in the perimenopausal women. Methods : Sixty perimenopausal included in a cross-sectional study from July to December 2016. Blood samples obtained from the women to measure the estradiol and the cortisol levels. Stress level measured with visual. Data presented as the mean and standard deviation (meanÂ±SD) with p-value <.05 was considered statistically significant. Results : There was no significant difference between the estradiol levels and the stress level (p=0.27) during perimenopause period. The estradiol levels were higher compared with the cortisol levels. The non parametrik correlations analysis show the estradiol levels were not correlated with the cortisol levels (p=0.352). However, the cortisol levels were correlated with the stress levels (p<0.05). Conclusion : Estradiol does not cause psychosocial stress during perimenopause period in our study population Keywords : Estradiol, psychosocial stress, perimenopause

The Effect of Cyclophosphamide Chemotherapy on Ovarian AntiMÃ¼llerian Hormone Levels in Breast Cancer Patients Elisabeth G.K. Liga; Nusratuddin Abdullah; Eddy Tiro; St. Maisuri T. Chalid
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To evaluate cyclophosphamide effects on Anti-MÃ¼llerian hormone (AMH) levels in breast cancer patientstreated with cyclophosphamide chemotherapy.Methods: This cohort prospective study was conducted inDr. Wahidin Sudirohusodo Hospital in the Department of Obstetricsand Gynecology in collaboration with Department of Surgery,Faculty of Medicice, Universitas Hasanuddin between September2015 and June 2016. Serum levels of AMH from forty breast cancerpatients received three series of cyclophosphamide chemotherapydetermined by Enzyme Linked Immuno Sorbent Assay (ELISA).Results: Serum AMH levels decreased significant in the first series(from 2.09ï‚±2.04 ïg/ml to o.65ï‚±1.06 ïg/ml; p<0.05) through thethird series (from 1.53ï‚±1.34 ïg/ml to 0.5ï‚±0.65 ïg/ml; p<0.05) ofcyclophosphamide chemotherapy.Conclusion: AMH levels decreased significant after cyclophosphamideindicated that cyclosphosphamide decrease ovarianreserve.[Indones J Obstet Gynecol 2018; 6-1: 64-67]Keywords: anti-mÃ¼llerian hormone, breast cancer, cyclophosphamide,ovarian reserveObjective: To evaluate cyclophosphamide effects on Anti-MÃ¼llerian hormone (AMH) levels in breast cancer patientstreated with cyclophosphamide chemotherapy.Methods: This cohort prospective study was conducted inDr. Wahidin Sudirohusodo Hospital in the Department of Obstetricsand Gynecology in collaboration with Department of Surgery,Faculty of Medicice, Universitas Hasanuddin between September2015 and June 2016. Serum levels of AMH from forty breast cancerpatients received three series of cyclophosphamide chemotherapydetermined by Enzyme Linked Immuno Sorbent Assay (ELISA).Results: Serum AMH levels decreased significant in the first series(from 2.09ï‚±2.04 ïg/ml to o.65ï‚±1.06 ïg/ml; p<0.05) through thethird series (from 1.53ï‚±1.34 ïg/ml to 0.5ï‚±0.65 ïg/ml; p<0.05) ofcyclophosphamide chemotherapy.Conclusion: AMH levels decreased significant after cyclophosphamideindicated that cyclosphosphamide decrease ovarianreserve.Keywords: anti-mÃ¼llerian hormone, breast cancer, cyclophosphamide,ovarian reserve

The Role of Matrix Metalloproteinase2 (MMP2) in Serum and Peritoneal Fluid of Endometriotic Patients NurIedil Baharuddin; Nusratuddin Abdullah; Telly Tessy; St Maisuri T Chalid
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 2 April 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To determine the role of matrix metalloproteinase-2(MMP-2) in serum and peritoneal fluid of endometrioticpatients.Methods: Researchâ€™s design using cross-sectional method in Dr.Wahidin Sudirohusodo hospital and several other hospitals inMakassar within May 2015 until May 2016. Subjects were chosenusing consecutive sampling technique. The examination usingthe ELISA method. The data were analysed using Fisher exact,t-independent, Mann-Whitney, and Spearman association.Results: A total of 50 subjects were recruited in this study. Mostlythe value of MMP-2 serum and peritoneal fluid in endometriosisgroup was higher compare to study control. There was significantdifferent between the total of MMP-2 serum and peritoneal fluid.There was also a significant association between the value ofMMP-2 serum and peritoneal fluid with endometriosis.Conclusion: The value of MMP-2 serum and peritoneal fluid werehigher in endometriotic patients compared to those withoutendometriosis. The higher the value of MMP-2 serum andperitoneal fluid, the higher the stage of endometriosis.[Indones J Obstet Gynecol 2018; 6-2: 104-109]Keywords: endometriosis, matrix metalloproteinase-2, MMP-2

Risk factors for stress urinary incontinence following vaginal and caesarean delivery: Faktor-faktor risiko stres inkontinensia urin setelah persalinan pervaginam dan perabdominam Nur Waqiah; David Lotisna; Nusratuddin Abdullah
Indonesian Journal of Obstetrics and Gynecology Volume 7, No. 1 January 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Abstract Background: Most of the stress urinary incontinence (SUI) occurs after first delivery and related to the mode of delivery. Objective: To determine the factors that affects the incidence of stress urinary incontinence post partum Methods: Women experienced with stress urinary incontinence 3 months after birth vaginally or section caesarean were enrolled in the present cross sectional study. The strength of the pelvic floor muscle measured with perineometer. All of women were assessed for SUI using Sandvix Severity Index (SSI) dan The three incontinence question (3IQ) questionnaire. A person chi-square test was used to analysis with p value <0.05 was considered significant. Results: Eighty-four women with stress urinary incontinence (SUI) after vaginal delivery or caesarean section enrolled in the study. There was a significant difference between mode of delivery and SUI following delivery (p<0.05). Perineal tear (grade 1-2), BMI, newborn weight and circumference significantly affect the SUI after vaginal or caesarean section. Perineal tear increase SUI after delivery 7-fold compared to other factors (OR=7.367; 95% CI=1.815-29.904). Conclusion : SUI after delivery affected by Mode of delivery, pelvic muscle floor weakness, perineal tear, BMI, newborn weight and head circumference. Keywords: stress urinary incontinence, mode of delivery Abstrak Latar belakang: Sebagian besar kasus stress inkontinensia urin terjadi setelah partus pertama kali dan berhubungan dengan metode persalinan. Tujuan: Untuk mengetahui faktor-faktor yang mempengaruhi terjadinya stress inkontinensia urin post partum Metode: Wanita yang mengalami stres inkontinensia urin 3 bulan postpartum normal atau seksio dilibatkan dalam penelitian cross sectional ini. Kekuatan otot dasar panggul diukur dengan perineometer. Penilaian SUI dilakuakn dengan menggunakan kuesioner Sandvix Severity Index (SSI) dan The three incontinence question (3IQ). Data dianalisis dengan uji Chi-square dengan tingkat kemaknaan p<0,05. Hasil: Delapan puluh empat wanita dengan SIU postpartum per vaginam atau operasi caesar dilibatkan dalam penelitian ini. Terdapat perbedaan signifikan antara cara persalinan dan SIU setelah postpartum (p<0,05). Ruptur perineum (grade 1-2), IMT, berat bayi lahir dan lingkar kepala secara signifikan mempengaruhi SIU postpartum. Ruptur perineum meningkatkan SUI postpartum 7 kali lipat dibandingkan dengan faktor-faktor lainnya (OR = 7,367; 95% CI = 1,815-29,904). Kesimpulan: SIU postpartum dipengaruhi oleh cara persalinan, kelemahan dasar otot panggul, robekan perineum, IMT, berat bayi lahir dan lingkar kepala. Kata kunci : stress inkontinensia urin, metode persalinan

Lidocaine Prilocaine Cream versus LidocaineHCL Injection for Pain Relief during Second Degree of Perineal Tear Suturing after Vaginal Delivery: A Comparative Study: Lidokain Prilokain Topikal versus Injeksi LidokainHCL dalam Menghilangkan Nyeri Selama Penjahitan Luka Perineum Tingkat Dua Pascapersalinan Pervaginam: Sebuah Studi Komparatif Rahmawati Rahmawati; David Lotisna; Nusratuddin Abdullah; Maisuri T Chalid; Telly Tessy
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Abstract Objective : To compare the effectiveness of topically applied lidocaine-prilocaine cream with lidocaine-HCl injection in the reduction of pain during second degree of perineal tear suturing after vaginal delivery. Methods : One hundred and twenty-four of women with second degree of perineal tear after vaginal delivery were enrolled in this randomized clinical trial. Women were assigned randomly to have either application of lidocaine-prilocaine cream (n=62) or local injection of lidocaine-HCl (n=62) for anesthetic during perineal suturing. Pain measured with viasual analog scale (VAS) for the first 5 minutes during the perineal suturing. Statistical analysis was performed by comparative analytic numerical unpaired with independent t test between the two groups and significance was assessed at p<0.05. Data were presented as mean Â± standard deviation (SD). Results : There was no significantly different of pain score between lidocaine-prilocaine cream and lidocaine-HCl injection group (5.66Â±1.07 vs 5.56Â±1.5; p=0.473). Conclusion : Application of lidocaine-prolicaine cream as effective as injection of lidocaine for reducing pain during second degree of perineal tear suturing after vaginal delivery. Keywords : Lidocaine-prilocaine cream, lidocaine-HCl injection, pain, perineal suturing, vaginal delivery Abstrak Tujuan: Untuk membandingkan efektivitas antara lidokain-prilokain topikal dan lidokain-HCl injeksi dalam mengurangi nyeri selama penjahitan luka perineum tingkat dua setelah persalinan normal. Metode: Seratus dua puluh empat perempuan dengan robekan perineum tingkat dua postpartum pervaginam mengikuti uji coba klinis secara acak ini. Enam puluh dua perempuan (n=62) menggunakan lidokain-prilokain topikal dan 62 perempuan lainnya (n=62) menggunakan injeksi lokal lidokain-HCl untuk anestesi selama penjahitan perineum. Nyeri diukur dengan visual analog scale (VAS) untuk 5 menit pertama selama penjahitan perineum. Analisis statistik dilakukan dengan uji numerik komparatif tidak berpasangan dengan uji t independen antara kedua kelompok dengan tingkat kemaknaan p<0,05. Data disajikan sebagai rerata Â± standar deviasi (SD). Hasil: Tidak terdapat perbedaan signifikan skor nyeri antara kelompok lidokain-prilokain topikal dan kelompok injeksi lidokain-HCl (5,66 Â± 1,07 vs 5,56 Â± 1,5; p = 0,473). Kesimpulan : Efektifitas lidokain-prolikain topikal untuk mengurangi nyeri sama dengan injeksi lidokain-HCl selama penjahitan robekan perineum tingkat dua postpartum pervaginam. Kata kunci : Lidokain-prolikain topical, lidokain-HCl injeksi, nyeri, penjahitan perineum, persalinan normal

Chlamydia Trachomatis Infection and Ectopic Pregnancy: Infeksi Chlamydia Trachomatis dan Kehamilan Ektopik Septian Sima; Nusratuddin Abdullah; Sharvianty Arifuddin; Trika Irinta; Telly Tessy
Indonesian Journal of Obstetrics and Gynecology Volume 8 No. 3 July 2020
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v8i3.1136

Objective: To determine the relationship of Chlamydia trachomatis infection in patient with ruptured ectopic pregnancy through examination of endocervical swabs, tubal tissue using Polymerase chain reaction (PCR) and Enzyme linked immunoabsorb and assay (ELISA) serum IgG antibodies Specific to Chlamydia trachomatis.Method: This study was an observational analytic study with a cross sectional study design. In this study, there were 50 participants consisting of 25 ruptured ectopic pregnancy patients and 25 non-ruptured ectopic pregnancy patients who underwent treatment at Dr.Wahidin Sudirohusodo Hospital as well as networking hospitals at the Universitas Hasanuddin in Makassar City.Results: The results showed that Chlamydia trachomatis infection in patients with ruptured ectopic pregnancies was found to be 84% positive in tubal tissue, 72% with endocervical swabs and 64% with serum examination. There was a significant relationship between chlamydial tracheal infection obtained through examination of tubal tissue, endocervical swab and specific serum IgG in patients with ruptured ectopic pregnancy (p <0.001).Conclusion: Based on the results of the study, it can be concluded that Chlamydia trachomatis infection can significantly affect the occurrence of ruptured ectopic pregnancy.Keywords: Chlamydia trachomatis, endocervical swab, ruptured ectopic pregnancy, serum IgG, tubal tissue. Abstrak Tujuan : Untuk mengetahui hubungan infeksi Chlamydia trachomatis pada pasien penderita Kehamilan Ektopik Terganggu (KET) melalui swab endoserviks dan jaringan tuba menggunakan pemeriksaan Polymerase Chain Reaction (PCR) dan Enzyme linked immunoabsorb and assay (ELISA).Metode : Penelitian ini merupakan studi analitik observasional dengan desain studi potong lintang. Pada penelitian ini terdapat 50 orang partisipan yang terdiri atas 25 orang pasien kehamilan ektopik terganggu dan 25 orang pasien non-kehamilan ektopik terganggu yang menjalani pengobatan di RSUP Dr.Wahidin Sudirohusodo serta RS jejaring Universitas Hasanuddin di Kota Makassar.Hasil : Hasil penelitian menunjukkan bahwa infeksi Chlamydia trachomatis pada pasien dengan kehamilan ektopik tergangu didapatkan sebesar 84% positif di jaringan tuba, 72% dengan swab endoserviks dan 64% dengan pemeriksaan serum. Terdapat hubungan yang signifikan antara infeksi klamidia trakomatis yang didapatkan melalui pemeriksaan jaringan tuba, swab endoserviks maupun serum IgG spesifik pasien kehamilan ektopik terganggu (p<0,001).Kesimpulan : Berdasarkan hasil penelitian, dapat disimpulkan bahwa infeksi Chlamydia trachomatis secara signifikan dapat mempengaruhi terjadinya kehamilan ektopik terganggu.Kata kunci : chlamydia trachomatis, jaringan tuba, kehamilan ektopik terganggu, swab endoserviks, serum IgG

Title

Found 11 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 11 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 11 Documents
Search