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All Journal Buletin Farmatera Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) JURNAL ILMIAH SIMANTEK Medicina Biomedica Journal
Dedi Ansyari
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health

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APO B/APO A-I RATIO IN PATIENTS WITH STENOSIS CORONARY HEART DISEASE GREATER OR LESS THAN 70% Dedi Ansyari; Tapisari Tambunan; Harris Hasan
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 23, No 3 (2017)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v23i3.1198

Abstract

Penyakit kardiovaskular adalah salah satu penyebab terbesar kematian di dunia, termasuk di Indonesia. Salah satunya adalahpenyakit jantung koroner yang disebabkan adanya aterosklerosis. Perlu adanya petanda pengganti proses aterosklerosis sebagai faktorkebahayaan dan sebagai peramal aterosklerosis dan PJK. Apo B dan rasio Apo B/Apo A-I dianggap sebagai petanda yang terbaik. Tujuanpenelitian untuk mengetahui rasio Apo B/Apo A-I di pasien PJK dengan stenosis lebih besar atau sama dengan 70% dan lebih kecil 70%.Metode penelitian dengan potong lintang di 69 pasien PJK, yaitu 46 pasien PJK dengan stenosis lebih besar atau sama dengan 70% dan23 pasien PJK dengan stenosis lebih kecil 70% di Departemen Kardiologi FK. USU/RSUP H. Adam Malik Medan bekerja sama denganDepartemen Patologi Klinik FK. USU/RSUP. H Adam Malik Medan masa waktu Juli 2015 sampai dengan November 2015. Hasil telitiandidapatkan kadar Apo B di pasien PJK dengan stenosis lebih besar atau sama dengan 70% adalah 115,63±30,96 dan pasien PJK denganstenosis lebih kecil 70% adalah 96,43±25,62 dengan nilai p=0,013. Kadar Apo A-I di pasien PJK dengan stenosis lebih besar atau samadengan 70% adalah 148,30±26,80 dan pasien PJK dengan stenosis lebih kecil 70% adalah 173,74±32,33 dengan nilai p=0,001. RasioApo B/Apo A-I di pasien PJK dengan stenosis lebih besar atau sama dengan 70% adalah 0,79±0,20, rasio Apo B/Apo A-I di pasienPJK dengan stenosis lebih kecil 70% adalah 0,55±0,14 dengan nilai p=0,0001. Dari hasil telitian dapat disimpulkan, bahwa terdapatperbedaan bermakna kadar Apo B, Apo A-I serta rasio Apo B/Apo A-I di pasien PJK dengan stenosis lebih besar atau sama dengan 70%dan pasien PJK dengan stenosis lebih kecil 70%.
HUBUNGAN KUALITAS TIDUR DENGAN TINGKAT KEBUGARAN JASMANI TERHADAP MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA ANGKATAN 2019 PUTRA, AIDIL TRI ERIA; ANSYARI, DEDI
JURNAL ILMIAH SIMANTEK Vol 8 No 1 (2024): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Physical fitness is a description of a person's physical condition or functional condition in carrying out various jobs or daily activities. The higher the level of physical fitness, the better the physical condition, so that they are able to do various jobs or workloads given and will be successful in completing the work. That way the ability or level of productivity is higher. To be able to do work or daily activities well, it takes good physical fitness as well. Healthy living habits are one of the factors that must be considered and can affect physical fitness, one of these habits is sleep. Sleep is a basic human need. Every human being needs time to rest and sleep to be able to restore stamina or good body condition so that they can do various jobs or daily activities. The purpose this research are to determine the relationship between sleep quality and physical fitness level for students of the Faculty of Medicine, University of Muhammadiyah North Sumatra, Class of 2019. Using an analytical method with a cross sectional approach, that is, each research subject will only be used once to determine the relationship between sleep quality and fitness level. physical student of the Faculty of Medicine, University of Muhammadiyah North Sumatra. The data of this study were obtained using the PSQI questionnaire and the Harvard Step Test. Data analysis using Chi Square test. The results showed that most of the respondents had poor sleep quality (64.4%) and most of them had a very poor level of physical fitness (57.8%). And there is a relationship between sleep quality and physical fitness level (p = 0.001).
Effectiveness of Fig Leaf Ethanol Extract (Ficus carica L.) As An Antidiabetes In Alloxan-Induced Diabetes Model in Rats Habibie, Muhammad Farhan; Ansyari, Dedi
Buletin Farmatera Vol 11, No 2 (2026): (In Progress)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.26745

Abstract

Abstract: Long-term use of diabetes mellitus medication can cause several complications, so oter alternative treatments are needed that tend to have safer effects, such as herbal treatments using fig plants. Researchers feel the need to test with different doses and subjects to determine whether fig leaf extract (Ficus carica L.) is effective as an antidiabetic in alloxan-induced diabetic mouse models. This research uses a true experimental method with a pretest-posttest with control group design. Sampling used the simple random sampling method. The samples used were 36 male white rats (Rattus norvegicus L.), which were divided into 6 groups. Data will be analysed using the paired sample T test, one-way ANOVA test, and Post hoc test. The results showed that administering ethanol extract of fig leaves at doses of 200 mg/KgBW, 400 mg/KgBW, and 600 mg/KgBW had effectiveness as an antidiabetic in reducing fasting blood sugar levels in rats induced by alloxan (p = 0.000). However, only the ethanol extract group of fig leaves at a dose of 600 mg/kg bw (P3) had antidiabetic activity that was as effective as the drug glibenclamide (p = 0.253). Administration of ethanol extract of fig leaves (Ficus carica L.) has antidiabetic effectiveness in a rat model of alloxan-induced diabetes.
USE OF CHLOROQUINE ON COVID-19 VIRUS INFECTION IN INDONESIA: STUDY OF LITERATURE Ansyari, Dedi
Medicina Biomedica Journal Vol 1, No 1 (2022)
Publisher : Medicina Biomedica Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/mbj.v1i1.9186

Abstract

BACKGROUND: COVID-19, which is caused by a new type of coronavirus, namely SARS-CoV-2, has become a disease that causes a public health emergency that is troubling the world. Chloroquine was initially reported as a potentially useful drug for COVID-19. The use of chloroquine has been reported in various countries in the world and also in Indonesia.AIM: This literature study aims to trace the use of chloroquine at the beginning of the COVID-19 pandemic until recently.METHODS: The method used is through searching articles published in national and international journals within the last 3 years.RESULTS AND CONCLUSION: From the search results, it can be concluded that chloroquine has not been proven to be useful in the management of COVID-19 patients and can cause severe side effects, its use is no longer recommended by WHO and also in Indonesia
Co-Authors Habibie, Muhammad Farhan Harris Hasan PUTRA, AIDIL TRI ERIA Tapisari Tambunan