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All Journal Jurnal Kesehatan Islam : Islamic Health Journal Jurnal Kedokteran Komunitas (Journal of Community Medicine)
Dian Novita W
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Jurnal Kesehatan Islam : Islamic Health Journal

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Uji Potensi Antioksidan Kumis Kucing (Orthosiphon aristatus) dengan Pendekatan In Vitro dan In Silico Dian Novita W; Silvy Amalia Falyani
Jurnal Kesehatan Islam : Islamic Health Journal Vol 10, No 2 (2021): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v10i2.13823

Abstract

Abstract: Orthosiphon aristatus is a potential herb as a source of antioxidants. It is known from previous research, that the active compounds O.aristatus include eupatorin, rosmarinic acid and sinensetin. The study of the potential approach of active compounds extracts O.aristatus with the in vitro methods DPPH (1,1-Difenil-2-Pikrilhidrazil) and in silico using the help of pyrex autodock vina software, with the help of visualization using biovia discovery studio and pymol. Results obtained from in vitro tests using DPPH showed the presence of antioxidant activity with yellow spotting markers against a purple background. Studies in silico show that O.aristatus extract is potentially an antioxidant compound, this is demonstrated through the presence of ligand bonds with glutathione peroksidase (GPX) receptors namely van der Waals bonds, hydrogen bonds and several other bonds.
Co-Authors Damayanti, Dini Sri Moh. Yahya Al-Hilal Silvy Amalia Falyani