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All Journal Jurnal Farmasi Indonesia Jurnal Pengabdian Masyarakat dan Riset Pendidikan
Kusumaningtyas Siwi A
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Education Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Other

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Aktivitas Antibakteri Kombinasi Ekstrak Etanol Daun Johar (Cassia siamea Lamk.) dan Daun Alpukat (Persea americana Mill.) terhadap Salmonella Typhi Hanugrah Ardya Crisdian; Kusumaningtyas Siwi A
Jurnal Farmasi Indonesia Vol 18 No 2 (2021): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v18i2.1172

Abstract

Typhoid fever is an acute febrile disease caused by Salmonella typhi bacteria, WHO 2018 data states that in the world it reaches 11-20 million cases per year, in Indonesia it reaches a prevalence rate of 358-810/100,000 population. The purpose of this study was to determine the antibacterial activity of the combination of johar leaves (Cassia siamea Lamk) and avocado leaves (Persea americana Mill) against the growth of salmonella typhi bacteria. Testing the antibacterial activity of a combination of 1:1 70% ethanol extract of johar leaves and avocado leaves by diffusion and dilution methods, treatment using control (+) ciprofloxacin and control (-) DMSO 2% with series concentrations of 25, 50, 75 and 100%. Each treatment was repeated 3 times. The results of the antibacterial activity test of the combination of ethanol extract of johar leaves and avocado leaves had the greatest activity against Salmonella typhi bacteria at a concentration of 100% with a clear zone diameter of 9.9 mm while the smallest average was at a concentration of 25% with a diameter of 6 mm, and ciprofloxacin with a diameter of 29.3 mm. The minimum inhibition level was at a concentration of 12.5%.
Formulasi dan Uji Mutu Fisik Sediaan Lulur (Scrub) Ekstrak Kulit Jeruk Nipis (Citrus Aurantifolia) dan Beras Putih (Oryza Sativa): Penelitian Alfi Risna Fadilla; Kusumaningtyas Siwi A; Tatiana Siska Wardani
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 3 No. 4 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 3 Nomor 4 (April 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v3i4.1232

Abstract

Body scrub is one of the cosmetic pharmaceutical products that functions to smooth the skin by removing dead skin cells. White rice (Oryza sativa) is used as abrasive material in making body scrubs. Lime peel contains more than 60% flavonoids and around 170 different types of phytonutrient compounds. Flavonoids are the main group of polyphenol compounds that have antioxidant properties. This study aims to identify the content of secondary metabolites in lime peel extract, test the physical quality standards of the body scrub, and determine the best body scrub formulation. The method used in this study is a laboratory experimental method. The extraction process was carried out using maceration techniques using 70% ethanol solvent. Furthermore, a phytochemical screening test was carried out to identify the content of active compounds, as well as physical testing on body scrub preparations with three different extract concentrations (2%, 3%, and 4%). In addition, a hedonic test was carried out to assess the level of preference and an irritation test to ensure product safety. Data analysis was carried out using One Way ANOVA to see the differences between formulas, and a Dependent T-test to test the level of preference for body scrub preparations. The results of the observation showed that lime peel (Citrus aurantifolia) contains various secondary metabolites, including flavonoids, alkaloids, tannins, saponins, terpenoids, and antioxidant compounds.
Co-Authors Alfi Risna Fadilla Hanugrah Ardya Crisdian Wardani, Tatiana Siska