Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Jurnal Farmasi Indonesia
Alfi Mahmudah
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
PENETAPAN KADAR FENOLIK DAN FLAVONOID SERTA AKTIVITAS INHIBISI ENZIM TIROSINASE FREEZE DRY JUS BUAH JAMBLANG (Syzygium cumini (L.) Skeels) Nani Suryani; Dimas Danang Indriatmoko; Alfi Mahmudah; Dodik Efendi
Jurnal Farmasi Indonesia Vol 19 No 1 (2022): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v19i1.1331

Abstract

The skin is the largest organ that protects the body from various traumas such as thermal, chemical, and ultraviolet radiation. Melanin biosynthesis is the conversion of L-Tyrosine (4-hydroxyphenylalanine) to L-DOPA (L-3,4-dihydroxyphenylalanine) with the help of the tyrosinase enzyme. Phenolics and flavonoids significantly affect the inhibition of tyrosinase activity. Phenolics and flavonoids are thought to be contained in the fruit of Syzygium cumini. This study aimed to determine the levels of phenolics and flavonoids and to determine the tyrosinase enzyme inhibitory activity of freeze-dried S. cumini fruit juice. The method used to determine the levels of phenolics and flavonoids using UV-Vis spectrophotometry and tyrosinase inhibition test using in vitro ELISA (Enzyme Linked Immunosorbent assay). S. cumini contains total phenolic is 0.13155 mg GAE/g and total flavonoid is 37,333 mgQE/g. Freeze dry fruit juice of S. cumini has potential as a tyrosinase enzyme inhibitor at 31.25 ppm (14.846%), 62.5 ppm (16.246%), 125 ppm (19.238%), 250 ppm (22.059%), 500 ppm (25.665). %), 1000 ppm (32.283%) and 2000 ppm (44.188%).
Co-Authors Dimas Danang Indriatmoko Dodik Efendi Nani Suryani