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All Journal Biotropika Sari Pediatri Islamic Review : Jurnal Riset dan Kajian Keislaman Jurnal Ilmu Pendidikan dan Bahasa
Riza Rahmawati
Biology department, Mathematic and Natural Science Faculty, Brawijaya University Malang
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Social Sciences Other

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Dexamethasone Activities toward Population of B cells, Gr-1, and TNF-α cytokine in Mice (Musmusculus) Balb/c Biliary Atresia Model Rahmawati, Riza
Biotropika: Journal of Tropical Biology Vol 2, No 2 (2014)
Publisher : Biotropika: Journal of Tropical Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (104.608 KB)

Abstract

Biliary atresia iscondition caused by Rotavirus (RRV) infection. The aims of this study were to know the immune responses of mice model of biliary atresia treated with corticosteroid.Mice were splitinto 3 treatment groups: control (K), RRV injection (R), and RRV injection in the present of dexamethasone(R+D). In R treatment, the baby mice born in <24 hours were injected with 20 µl of phosphate buffered saline containing 1.5 x 106 fluorescence-forming units Rhesus Rotavirus (RRV). First termination was performed in the day 7 to 14, while second termination was done in the day 14 to 21. The dosage of dexamethasone which is applied in this experiment is 0.5mg/kg body weight.Immunocompetent cells were isolated from spleen,  and cell surface molecules were then analyzed by flowcytometry. The data was tested by SPSS 16.0 for Windows program. The results showed that dexamethasone given as corticosteroid for biliarry atresia theurapy couldsuppress TNF-αproduction as well as Gr-1 proliferation. In the other hand dexamethasonecan promote B220+ cell proliferation inrotavirus infected mice. Key word: Baby mice, biliary atresia, dexamethason, flowcytometry, rotavirus
Pancasila as State Ideology and Pillar of Religious Harmony in Indonesian Society Nurdianzah, Erry; Azizah, Nurul; Rahmawati, Riza; Munib, Ahmad; Sulistyowati, Octalia Heri; Albary, Hanifah
Islamic Review: Jurnal Riset dan Kajian Keislaman Vol 13 No 2 (2024): October 2024
Publisher : Mafapress - Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) IPMAFA Pati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35878/islamicreview.v13i2.1201

Abstract

Religious diversity in a country is natural, but even so, an arrangement within the country is needed to accommodate differences in religion and belief. Without a fair arrangement, this can make the state less stable and cause religious conflicts in a country.This article examines Pancasila as the state ideology in forming religious tolerance. This research is a qualitative research with a literature study approach, namely by using books, documents, journals and other related sources as sources of research data. This study discussed about Pancasila as state ideology and religion, Pancasila Philosophy in Islamic Views, and Pancasila as an ideology forming religious tolerance. While data analysis is carried out by grouping, sorting and then looking for themes that are in accordance with the focus of research for later interpretation. Results of studi show;1) Pancasila as the state ideology has been fully supported by religious normativity. 2) The values and norms contained in Pancasila have compatibility with the values that become the teachings of Islam. and 3) Pancasila plays an important role in creating religious tolerance, mutual respect and respect for adherents of other religions, and not forcing beliefs on other parties.
Model Pendidikan Islam Holistik: Menjawab Kebutuhan Pembentukan Karakter di Era Revolusi Industri 4.0 Rahmawati, Riza; Saputra, Dedi
Mandalika: Jurnal Ilmu Pendidikan dan Bahasa Vol 3 No 2 (2025): Mandalika Jurnal Ilmu Pendidikan dan Bahasa
Publisher : Mandalika Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59613/jipb.v3i2.304

Abstract

The Fourth Industrial Revolution has had a profound impact on education, particularly in shaping students’ character. Holistic Islamic education emerges as an integrative approach that unites intellectual, spiritual, emotional, and social aspects to address both moral challenges and the demand for 21st-century competencies. This study aims to formulate a holistic Islamic education model relevant to character building for the younger generation in the digital era. This research employs a qualitative method with a literature review design, applying content analysis. Data were collected from scholarly articles, conference proceedings, books, and official documents, and then analyzed through data reduction, thematic categorization, and synthesis of findings. Source triangulation was applied to ensure validity. The findings reveal that holistic Islamic education effectively integrates religious values with 21st-century skills, such as critical thinking, creativity, communication, and collaboration. The model emphasizes four main dimensions: spirituality (faith and morality), intellectual (knowledge and technology mastery), socio-emotional (empathy and responsibility), and digital-ethics (Islamic-based digital literacy). Practices in Islamic schools and pesantren in Indonesia and Malaysia demonstrate the effectiveness of this model in shaping students who are morally grounded, adaptive, and competitive. Thus, this study highlights the urgency of holistic Islamic education in addressing the challenges of the Fourth Industrial Revolution. The proposed model offers an alternative framework for preparing a globally competitive Muslim generation while preserving their religious identity.
Nilai Prediktif Indeks Imun Inflamasi Sistemik terhadap Kejadian Dengue Berat pada Anak: Sebuah Studi Kohort Retrospektif Rahmawati, Riza; Indrawanti, RR. Ratni; Pangarso, Alexandra
Sari Pediatri Vol 27, No 6 (2026)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp27.6.2026.415-22

Abstract

Latar belakang.Indonesia adalah salah satu negara endemik dengue. Pada tahun 2022, jumlah kasus dengue di Indonesia sebanyak 143.000 dengan insiden 52/100.000 penduduk, dan fatality rate 0,9%. Proporsi kasus anak sebesar 49%, sementara proporsi kematian anak mencapai 70%. Manifestasi klinis dengue sangat dipengaruhi oleh respons inflamasi sistemik, seperti rasio neutrofil-limfosit (RNL) dan indeks imun inflamasi sistemik (IIS). Nilai RNL dan IIS pada fase demam dapat digunakan untuk memprediksi dengue berat pada anak.Tujuan. Untuk mengetahui apakah RNL dan IIS dapat digunakan sebagai prediktor dengue berat pada anak.Metode. Penelitian ini merupakan studi observasional analitik dengan kohort retrospektif. Populasi penelitian adalah anak usia 1-18 tahun dengan demam dengue sejak Januari 2019 sampai Juni 2024 di RS Sardjito, Yogyakarta. Profil hematologi diambil pada demam hari ke-2 hingga ke-4. Data RNL dan IIS lalu dianalisis menggunakan kurva receiver operating characteristic (ROC) dan ditentukan titik potong dengan Youden Index, kemudian dilakukan analisis multivariat.Hasil. Didapatkan 530 pasien demam dengue dalam periode penelitian dan hanya 97 pasien yang memenuhi kriteria inklusi maupun eksklusi. Tidak ada perbedaan secara statistik untuk karakteristik jenis kelamin, obesitas, dan status infeksi sekunder pada luaran dengue berat dan dengue tidak berat. Nilai IIS <73.050,89 (p<0,05; RO 6,95; IK95% 1,97 – 24,61), usia 1-5 tahun (p<0,05; RO 5,56; IK95% 1,59 – 19,32), dan usia 6-10 tahun (p<0,05; RO 4,58; IK95% 1,54 – 13,61) merupakan prediktor dengue berat, sementara RNL (p<0,17; RO 0,40; IK 95% 0,11 – 1,48) tidak dapat dijadikan prediktor.Kesimpulan. Nilai IIS ?73.050,89, usia 1-5 tahun, dan usia 6-10 tahun merupakan prediktor kejadian demam berdarah (dengue) berat pada anak.
Co-Authors Albary, Hanifah Dedi Saputra Indrawanti, RR. Ratni Munib, Ahmad Nurdianzah, Erry NURUL AZIZAH Pangarso, Alexandra Sulistyowati, Octalia Heri