Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Medical Journal of Indonesia The New Ropanasuri Journal of Surgery Jurnal Penyakit Dalam Indonesia
Muchlis Ramli
Department of Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta.
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

Published : 22 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 22 Documents
Search

 1   2   3 
Purse-String Suture for Skin Closure Following Large Thyroidectomy Kurnia, Ahmad; Siregar, Bintang Abadi; Ramli, Muchlis
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. The total number of patients with thyroid nodules, especially large thyroid nodules (> 6 cm diameter), is increasing. However, the conventional suturing technique for closure of thyroidectomies is still only recommended as the standard for the tumor with a diameter up to 6 cm. Hence, this study aims to prove another surgical technique, purse-string stitching technique, for better esthetic outcomes on large thyroidectomy. Methods. This study was a non-randomized control trial. The subjects included the patients of Cipto Mangunkusumo Hospital in 2013 to 2014 with a thyroid tumor > 6 cm in diameter without any history of anterior cervical surgery and positive lymph nodes. Subjects were divided into the purse-string group and the conventional group. Thyroidectomies were done on all subjects, then were closed by the suturing technique of each group. Outcomes were recorded in the follow-up sessions, including wound scar size, wrinkle existence, and subject’s satisfaction level. Results. Purse-string technique resulted in shorter scar length compared to the conventional technique (median 35 mm vs. 94 mm, p< 0.01). The other outcomes, such as the width of the scar (median 3 mm vs. 2 mm, p=0.265), the presence of wrinkles (0 vs. 2, p=0.480), and satisfaction level of subjects (median 9 vs. 9, p=0.287) were also assessed. Conclusion. The purse-string suturing technique on large thyroidectomy wound closure could be an alternative, besides the conventional suturing technique for a better esthetic result.
The Changes of Amino Terminal Pro B-type Natriuretic Peptide(NT-proBNP) Concentration and Left Ventricular EjectionFraction on Doxorubicin Chemotherapy Patients Kamelia, Telly; Waspadji, Sarwono; Makmun, Lukman Hakim; Effendi, Shufrie; Ramli, Muchlis; Timan, Ina Susanti
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Cancer patients who received chemotherapy regimen containing doxorubicin has been known to have serious side effect in heart, called as cardiotoxicity. The measurement of NT-proBNP proposed to be used as a new parameter to identify and evaluate cardiotoxicity in cancer patients earlier before it has been manifested, superior than measurement of left ventricle ejection fraction (LVEF). The aims of this study to examine the changes of NT-proBNP concentration and LVEF on patients with cancer who receive chemotherapy regimen containing doxorubicin. Methods. The study used pre and post test design to observe the changes of NT-proBNP concentration and LVEF on the patients who receive naïve doxorubicin chemotherapy and after chemotherapy-cycle I to cyce IV at the Ciptomangunkusumo hospital, Jakarta. Echocardiography and NT-proBNP were examined on naïve chemotherapy and after chemotherapy each cycle. Statistical analysis was performed by using two way Anova and Friedman nonparametric test. Results. During the period of October 2007 to June 2008, a total of 29 consecutive patiets receiving doxorubicin chemotherapy regimen CHOP (Cyclophosphamide, doxorubicin, Vincristine, Prednisone and FAC-5 Fluorouracil, doxorubicin, Cyclophosphamide) were collected. The increase of median NT-proBNP concentration between naïve chemotherapy and: post chemotherapy cycle I was 32 pg/mL (12,5-124,6 pg/mL), post chemotherapy cycle II was 135 pg/mL (44-275,2 pg/mL), post chemotherapy cycle III was 275,1 pg/mL (97,8-907,2 pg/mL), post chemotherapy cycle IV was 514,6 pg/mL (80,6-6458,2 pg/mL). With Friedman test, p< 0,000. With Anova two way test, it was found the difference between naïve LVEF and LVEF: post chemotherapy cycle I was 5,1% (p 0,000), post chemotherapy cycle II 8,9% (p 0,000), post chemotherapy cycle III 11,2% (p 0,000), post chemotherapy cycle IV 12,5% (p 0,000). Conclusions. Elevated NT-proBNP concentration and LVEF reduction had been observed in doxorubicin chemotherapy patients.
Co-Authors Ahmad Tjarta Didid Tjindarbumi Drupadi Dillon Drupadi S. Dillon Endang Hardjolukito Endang S. Roostini Esti Soetrisno Goi Sakamoto Gunawan Tjahjadi Idral Darwis Idwal Darwis Ina Susanti Timan, Ina Susanti Joedo Prihartono Kenji Wakai Kenzi Wakai Kurnia, Ahmad Lukman Hakim Makmun Nakako Kubo Primariadewi Rustamadji Sadao Suzuki Santoso Cornain Sarwono Waspadji Setiawati Budiningsih Setyawati Budiningsih Shufrie Effendi, Shufrie Siregar, Bintang Abadi Susilowati Herman Susumu Watanabe Telly Kamelia Yoshiyuki Ohno Yoshiyuki Ohno Ohno