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All Journal Medica Hospitalia The New Ropanasuri Journal of Surgery
Siregar, Bintang Abadi
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Purse-String Suture for Skin Closure Following Large Thyroidectomy Kurnia, Ahmad; Siregar, Bintang Abadi; Ramli, Muchlis
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

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Abstract

Introduction. The total number of patients with thyroid nodules, especially large thyroid nodules (> 6 cm diameter), is increasing. However, the conventional suturing technique for closure of thyroidectomies is still only recommended as the standard for the tumor with a diameter up to 6 cm. Hence, this study aims to prove another surgical technique, purse-string stitching technique, for better esthetic outcomes on large thyroidectomy. Methods. This study was a non-randomized control trial. The subjects included the patients of Cipto Mangunkusumo Hospital in 2013 to 2014 with a thyroid tumor > 6 cm in diameter without any history of anterior cervical surgery and positive lymph nodes. Subjects were divided into the purse-string group and the conventional group. Thyroidectomies were done on all subjects, then were closed by the suturing technique of each group. Outcomes were recorded in the follow-up sessions, including wound scar size, wrinkle existence, and subject’s satisfaction level. Results. Purse-string technique resulted in shorter scar length compared to the conventional technique (median 35 mm vs. 94 mm, p< 0.01). The other outcomes, such as the width of the scar (median 3 mm vs. 2 mm, p=0.265), the presence of wrinkles (0 vs. 2, p=0.480), and satisfaction level of subjects (median 9 vs. 9, p=0.287) were also assessed. Conclusion. The purse-string suturing technique on large thyroidectomy wound closure could be an alternative, besides the conventional suturing technique for a better esthetic result.
Breast Cancer Metastases Based on Molecular Subtypes at RSUD Dr. H. Abdul Moeloek Lampung Nurmayeni; Islamy, Nurul; Tjiptaningrum, Agustyas; Siregar, Bintang Abadi; Kusumaningtyas, Aditya; Windarti, Indri
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 3 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i3.904

Abstract

BACKGROUND:Breast cancer is the most common cancer in Indonesia and is a leading cause of cancer-related deaths in the country. Metastases are responsible for most deaths among breast cancer patients. Breast cancer is typically classified into four subtypes based on immunohistochemistry: luminal A, luminal B, HER2+, and TNBC. OBJECTIVE:To determine the association between the metastatic pattern of breast cancer and their molecular subtypes at RSUD Dr. H. Abdul Moeloek Lampung. METHOD:This study was an observational analytic study with a cross-sectional design. The sample comprised 81 individuals who had suffered from breast cancer and were recorded in the medical records section of RSUD Dr. H. Abdul Moeloek Lampung between 2013 – 2021 and met the inclusion and exclusion criteria. The association between breast cancer subtypes and the incidence and metastase sites were tested using the Chi-Square test. RESULT:This study found a significant association between breast cancer subtypes and the incidence of metastases (p <0.05). The TNBC subtype had a more frequent rate of metastases (34.5%) than the other subtypes (31% luminal B, 20.7% luminal A, and HER2+ 13.8%). The study also revealed a relationship between ER status and the incidence of metastases (p < 0.05). The luminal A subtype tends to metastasize to the liver, luminal B tends to metastasize to the bone, HER2+ tends to metastasize to the lung and liver, and TNBC tends to metastasize to the lung. However, no significant association was found between breast cancer subtypes and metastatic sites. CONCLUSION:There was a significant association between breast cancer subtypes and the incidence of metastases, but not with the metastatic sites.  
Co-Authors Agustyas Tjiptaningrum Indri Windarti Kurnia, Ahmad Kusumaningtyas, Aditya Muchlis Ramli Nurmayeni Nurul Islamy