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All Journal Jurnal Kedokteran Brawijaya Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Indonesian Journal of Urology Folia Medica Indonesiana
Johan Renaldo
Department Of Urology, Faculty Of Medicine, Universitas Airlangga, Dr Soetomo Hospital, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Complication of trans-rectal prostate biopsy based on Clavien index: 5 years of experience Adhitya Fajar Prasetya; Johan Renaldo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 53, No 3 (2021)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (15.032 KB) | DOI: 10.19106/JMedSci005303202107

Abstract

Trans-rectal prostate biopsy has become the gold standard for early diagnosis of prostate cancer in developing countries. Despite its low risk, there are some post-procedural complications. The complications are classified by using a modified Clavien-Dindo system. The study aimed to recognize complications of trans-rectal prostate biopsy procedure by using Clavien-Dindo classification index. All patients undergoing trans-rectal prostate biopsy procedure in the Department of Urology, Dr. Soetomo General Hospital between January 2015-December 2019, were retrospectively analyzed in terms of post-procedural complaints, underlying comorbidities and ongoing additional examinations. The complaints were compiled into Clavien-Dindo classification. Univariate analysis of various predictors of post-procedural complications was also conducted. It was found 98 complication events from 400 patients (24.5%). Most complications were 1st degree (dysuria, hematuria, urinary retention, fever, rectal pain and bleeding, erectile dysfunction, and constipation).  In univariate analysis, positive results of urinary culture correlated to the emergence of post-procedural complications. In conclusion, the incidence of post-trans-rectal prostate biopsy complication in Dr. Soetomo General Hospital reached 24.5%. From all of the risk factors, positive urinary culture is related to the post-biopsy complication. Most complications are in the 1st grade of Clavien index, suggesting that the procedure is relatively safe and has a low risk
Risk Factors of Urethro-cutaneous Fistula Development in Hypospadias Surgery Wien Permana; Tarmono Tarmono; Johan Renaldo
Jurnal Kedokteran Brawijaya Vol. 31 No. 3 (2021)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2021.031.03.9

Abstract

Urethrocutaneous fistula development is the most common complication found hypospadias surgery. Several factors associated with the incidence of fistulas are the age at the time the surgery. The type of hypospadias, the degree of chordae, the operative technique applied and catheter type. This study aimed to determine the risk factors associated with the urethro-cutaneous fistula development in hypospadias surgery. The results showed that from 310 hypospadias patients undergoing urethroplasty, urethra cutaneous fistula development occurred among 105 patients (30.6%) with a mean age of surgery 10.89+6.27 years. Hypospadias type has a significant difference with the incidence of urethro-cutaneous fistula development (p = 0.027). Age (p = 0.615), degree of chordae (P=0.805), operative technique (P=0.901) and catheter type (P=691) do not have a significant impact to urethro-cutaneous fistula development. It can be concluded that operative urethroplasty has a risk of urethra-cutaneous fistula that associated with hypospadias type.
BACTERIAL PATTERNS AND URINE CULTURE SENSITIVITY DESCRIPTION OF UROLOGY PATIENTS IN THE PAEDIATRIC POPULATION AT TERTIARY HOSPITAL Permata, Veryne Ayu; Renaldo, Johan; Vermasari, Naritha
Indonesian Journal of Urology Vol 32 No 2 (2025)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v32i2.1050

Abstract

Objective: The aim of this research is to determine trends in urine culture and antibiotic resistance in pediatric urology patients in Soetomo General Hospital, January 2021-December 2023. Material & Methods: Medical record data and the microbiology laboratory database were studied retrospectively using a descriptive method. Identification of the pattern of antibiotic sensitivity for bacterial infection is the objective of the present study. Results: The most frequent bacteria cultured from 1,234 urine samples were: Escherichia coli 45%, Klebsiella pneumoniae 25%, and Pseudomonas aeruginosa 15%. E. coli exhibited high sensitivity to Meropenem (95%), Imipenem (93%), and Amikacin (90%), but strong resistance to Ampicillin (75%), Trimethopral-Sulfamethoxazole (70%), and Ciprofloxacin (65%). K. pneumoniae also displayed comparable resistance patterns. pneumoniae and P. aeruginosa, whose resistance to several drugs over the research period was clearly increasing. Conclusion: In summary, for juvenile uropathogens carbapenems and amikacin are still quite powerful therapeutic choices. These results highlight the critical requirement of responsible antibiotic use and continuous antimicrobial resistance surveillance in order to counteract increasing resistance trends and protect efficient treatment possibilities for children. Keywords: Urinary Tract Infections, Pediatric urology, Antibiotic resistance, Uropathogens, Escherichia coli
IMPACT OF COVID – 19 ON UROLOGICAL INTERVENTIONS AT TERTIARY REFERRAL HOSPITAL Subihardi, Lalu Muhammad Editia; Renaldo, Johan; Soebadi, Mohammad Ayodhia
Indonesian Journal of Urology Vol 30 No 2 (2023)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v30i2.838

Abstract

Objective: This study aims to identify and evaluate the impact of COVID-19 on urological interventions at Soetomo general-academic hospital as the tertiary referral center. Material & Methods: This study is a descriptive-retrospective, single-center study that included all confirmed cases of COVID-19 in urological patients from March 1, 2020 until December 31, 2021 at Soetomo general-academic hospital. We investigated these patients' characteristics, focusing on the demography, clinical data, and eventual outcome. Patient's gender, age, primary urological presentation, COVID-19-related symptom, comorbidity, chest x-ray result, and laboratory value were among the involved variables. The patient's outcome was categorized into death, delayed intervention, or intervention as scheduled. Results: Seventy-seven patients were enrolled, with a mean age of 44.2 years. Fever was found in 42 (54%) patients and respiratory symptoms in 32 (41.5%) patients. An NLR value of >6 was found in 55.8% of patients. A total of 18 patients experienced LUTS (23.4%), 33 patients presented with hematuria (42.9%), and 30 patients had urinary tract infections (39%). Nineteen out of 77 patients (27.3%) died before intervention. On the other hand, surgical intervention in 37 (66%) patients were delayed due to self-isolation, while intervention in 19 (34%) patients was performed as scheduled due to their emergency nature. Conclusion: Urological patients infected with COVID-19 were impacted by the delay of surgical procedures and mortality in the first 22 months of the pandemic.
Urogenital Fistula Patients Profile at a Tertiary Hospital in Surabaya, Indonesia from 2015 to 2021 Jamhari, Muhammad Arif Hakim; Soebadi, Mohammad Ayodhia; Renaldo, Johan
Folia Medica Indonesiana Vol. 58, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Highlights: • Vesicovaginal fistula is the most common urogenital fistula. • The transvaginal approach is preferred in treating urogenital fistula. Abstract: A fistula is an extra-anatomical channel between two or more hollow organs, or between an organ and the body surface. WHO estimated there were two million patients with untreated urogenital fistula, with 130,000 new cases every year. The ideal approach for urogenital fistula depends on surgeon preference and individual clinical characteristics. Accordingly, we aimed to determine the profile of patients with a urogenital fistula at a tertiary hospital of Dr. Soetomo General Academic Hospital in Surabaya, Indonesia, from 2015 to 2021. A retrospective study with a descriptive design was carried out by medical records data retrieval of patients with urogenital fistula. It included age, etiology, anatomical location, surgical management, and recurrence rate. The study population consisted of 55 patients. The majority of the patients were among the 41-50 y.o. age groups (41.17%), while the least were in the <20 years group (1.96%). History of obstructed labor was the most common etiology (70.59%). Fistulas in the study population were also associated with a history of trauma (15.68%) and malignancy (11.76%). The vesicovaginal fistula was the most common type of fistula (88.23%). Other types found include urethrovaginal, ureterovaginal, rectovesical, rectovaginal, and vesicocolon fistulas. The transvaginal approach was preferred in almost all study populations. A total of two cases of vesicovaginal fistula recurred (3.39%). In general, patients with urogenital fistula are prevalent in the 4th decade age group, with the most common etiology being a history of obstructed labor. Transvaginal surgery is the treatment of choice with good results and low recurrence rates.
Correlations Between Staging and Chemotheraphy Response with Testicular Carcinoma Non-Seminoma at Dr. Soetomo Hospital, Surabaya, Indonesia Nugroho, Ahmad; Renaldo, Johan; Djatisoesanto, Wahjoe
Folia Medica Indonesiana Vol. 56, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

The purpose of this study to describe patientscharacteristics, correlation between stagingnon-seminomacancer and chemotherapyresponse. Data on age, location of tumor, staging, serum levels of the tumor marker post operative, adjuvant therapy, chemotherapy side effects, and response of patient to chemotherapy were gained from medical records inSoetomo Hospital Surabaya from January 2012 to December 2015, and analyzed with SPSS. Correlation between staging and chemotherapyresponse, correlation primary tumor staging (pT) and Metastasis (M), correlation regional lymph nodes staging (N) and metastasis (M), correlation serum tumor marker and chemotherapy response was proccessed by Spearman correlation test. There were no significant correlation between pT staging and M and no significant correlation between N and M staging. Based on tumor markers (S), mostly patients were S2. There were no significant correlation between the response to chemotherapy and serum tumor marker levels. In category of staging group, the mostare 14 patientsstage III. BEP was the most adjuvant Chemotherapy.Nausea and vomiting were The most complained during chemotherapy. Anemia were the most hematologic side effects of chemotherapy.There are no significant correlation between the staging of non-seminoma and the response to chemotherapy. Conclusion: Non seminoma mostly happened in young males. Non-seminoma responses to chemotherapy. Patients in early stage would give a good response to chemotherapy compared to those with advanced stage. After chemotherapy, evaluation should be done to the patients' complaints and complete blood count to detect side effects.
Pre-Operative Hormonal Administration in Hypospadias Patients Undergoing Urethroplasty Ramadhani, Muhammad Zaniar; Renaldo, Johan
Folia Medica Indonesiana Vol. 58, No. 1
Publisher : Folia Medica Indonesiana

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Abstract

Highlight: • The gold standard therapy of hypospadias is reconstructive surgery. • Glans diameter and penile length are factors influencing urethroplasty outcomes. • Many studies are being conducted to investigate various methods of increasing the size and diameter of the penis prior to the operation in order to reduce complications. • Preoperative testosterone hormonal therapy is able to reduce overall complication and urethrocutaneous fistula in hypospadias patient undergoing urethroplasty. Abstract: The gold standard of treatment for hypospadias patients is reconstructive surgery. The result and post-operative complication of urethroplasty were affected by glans diameter and penile length. Pre-operative testosterone administration, both parenterally or topically, has become one of the main interests to increase the size and diameter of penis to minimize post-operative complications. However, there has not been enough evidence to justify this recommendation. Therefore, we aimed to perform a systematic review and meta-analysis to evaluate the role of pre-operative testosterone to prevent postoperative complications after urethroplasty in hypospadias patients. Online databases of Medline, Scopus and Embase were searched until October 2021 to identify RCT studies evaluating the effect of testosterone hormone therapy in reducing post-operative complication on hypospadias patient undergoing urethroplasty. Data analysis was performed using RevMan 5.4. A total of 4 RCTs were included in the analysis of this study with the total of 211 patients. Pre-operative testosterone hormonal therapy significantly reduced the overall complications group (OR=0.17; 95% CI=0.04, 0.77; p=0.02), post-operative urethrocutaneous fistula (OR=0.4, 95% CI=0.19, 0.83, p=0.01). Finally, there was no significant effect on the incidence of dehiscence and meatal stenosis with OR of 0.59, 95% CI=0.23, 1.54, p = 0.28, and 0.277; 95% CI=0.04, 1.65; p=0.16, respectively. Pre-operative testosterone hormonal therapy could reduce overall complication and urethrocutaneous fistula in hypospadias patients undergoing urethroplasty.
THE PROFILE OF URINE CULTURE IN PEDIATRIC PATIENTS WITH UPPER URINARY TRACT DILATATION AT DR. SOETOMO GENERAL HOSPITAL FROM 2020-2023. Aji, Iwan Purnomo; Renaldo, Johan; Vermasari, Naritha
Indonesian Journal of Urology Vol 33 No 1 (2026)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v33i1.1122

Abstract

Objective: To describe the bacteriologic profile and antimicrobial-susceptibility patterns of urine cultures from pediatric UUTD patients treated at Dr Soetomo General Hospital, Indonesia, between 2020 and 2023. Material & Methods: This retrospective descriptive study reviewed medical records of 154 inpatients aged 0–17 years with confirmed UUTD. Demographic data, cultured species, and antibiotic susceptibilities were extracted and reported as frequencies. Results: From 154 bacterial isolates, Gram-negative bacteria dominated (78.6%) compared to Gram-positive (21.4%). The most frequent species were Escherichia coli (31.8%), Pseudomonas aeruginosa (16.9%), and Klebsiella pneumoniae (12.3%). Antibiotics with the highest sensitivity against major uropathogens were amikacin (83.7%), piperacillin-tazobactam (77.6%), and meropenem (81.6%). In contrast, gentamicin and nitrofurantoin demonstrated lower sensitivities, 61.2% and 71.4%, respectively. Severe hydronephrosis occurred in 52.6% of cases and was associated with more resistant bacterial isolates. Conclusion: Urinary tract infections in pediatric UUTD patients at Dr. Soetomo General Hospital are predominantly caused by Escherichia coli, with the highest antibiotic sensitivities observed for amikacin, meropenem, and piperacillin-tazobactam. Gentamicin and nitrofurantoin should be administered based on culture results, especially for uncomplicated cystitis. Regular antibiotic resistance surveillance is essential to ensure effective empirical treatment. Keywords: Urine Culture, hydronephrosis, pediatrics, antibiotic, Escherichia coli.
Co-Authors A.A. Ketut Agung Cahyawan W Adhitya Fajar Prasetya Aji, Iwan Purnomo Diansyah, Ramzie Nendra Doddy M Soebadi Doddy M. Soebadi Efendi, Ferdyan Rachmat Jamhari, Muhammad Arif Hakim Kusuma, Raditya Laksmana, Wisnu Lukman Hakim Mohammad Ayodhia Soebadi Muhammad Arif Hakim Jamhari Muhammad Ridha Muhammad Zaniar Ramadhani Nugroho, Ahmad Nurakbariansyah, Rocky Permana, Wien Pramanta, Aditya Ramadhani, Muhammad Zaniar Subihardi, Lalu Muhammad Editia Sunaryo Hardjowijoto Tarmono Djojodimedjo Vermasari, Naritha Veryne Ayu Permata wahjoe djatisoesanto Waskito, Dwi Wien Permana