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All Journal Jurnal Respirologi Indonesia Jurnal Multidisiplin Indonesia
Putri Eyanoer
Universitas Sumatera Utara
Education Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Veterinary

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Correlation Between Wood Dust Levels with Interleukin-8 in Blood Serum Wood Processing Workers at X Company, Tanjung Morawa Jubilette Windy Hutabarat; Nuryunita Nainggolan; Amira Permatasari Tarigan; Putri Eyanoer
Jurnal Respirologi Indonesia Vol 40, No 1 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i1.94

Abstract

Backgrounds: Wood dust exposure can stimulate proinflammatory cytokines and increase IL-8 levels, which is a foreign body in the body will be phagocytosis by macrophages and excrete mediators such as chemokines, cytokines, and chemoattractants which can cause inflammation. Duration of exposure, number and size of wood dust in the respiratory tract of wood industry workers are associated with various pulmonary disorders such as, COPD, occupational asthma, allergic rhinitis, decreased pulmonary function and pulmonary fibrosis. The aim this study is determine correlation between wood dust levels with interleukin-8 in blood serum among wood processing workers at x company, Tanjung Morawa-North Sumatera. Methods: A cross-sectional study which involved 40 workers from 3 different locations namely cutting, sanding and drafting. Cumulative wood dust exposure was calculated by measuring the dust content at the work site using Dusttrak TSI. IL-8 serum levels were measured using the ELISA technique. The Spearman correlation test was used. Results: Out of 40 workers those who worked in the cutting section were 15 people (37,5%), sanding section were 15 people (37,5%) and drafting section were 10 people (25%). The average level of wood dust PM 2,5 was 5,23 mg/m3while PM10 was 8,24 mg/m3 and the mean level of IL-8 in serum was 163,3 ng/L. This study find that there is a strong correlation between wood dust and IL-8 serum (r = 0,683; p
Overview of Functional Capacity and Quality of Life of Chronic Obstructive Pulmonary Disease (COPD) Patients Rizki Rahmadani Dalimunthe; Pandiaman Pandia; Amira Permatasari Tarigan; Putri Eyanoer
Jurnal Multidisiplin Indonesia Vol. 5 No. 6 (2026): Jurnal Multidisiplin Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jmi.v5i6.2767

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is one of the leading causes of morbidity and mortality worldwide, with a significant impact on patients’ functional capacity and quality of life. This study aims to describe the functional capacity and quality of life of COPD patients at Prof. Dr. Chairuddin P. Lubis Hospital. This study is a descriptive observational study with a serial case design. The research subjects were stable COPD patients who met the inclusion and exclusion criteria, using a convenience sampling technique. Data collected included demographic characteristics, inhaled bronchodilator therapy, functional capacity measured using spirometry and the six-minute walking distance (6MWD) test, and quality of life assessed using mMRC and CAT scores. Statistical analysis was performed using descriptive methods. A total of 110 patients participated in the study; the majority were aged 60–69 years (69.6%) and male (78%). Mean FEV?/FVC, FEV?, FVC, and 6MWD scores were higher in the tiotropium group compared with the indacaterol/glycopyrronium group. The mean CAT score indicated slightly worse quality of life in the indacaterol/glycopyrronium group (10.9 vs. 9.9). The majority of patients had cardiovascular-related comorbidities (20.9%). Tiotropium therapy showed better results in functional capacity compared with indacaterol/glycopyrronium, while quality of life was influenced by COPD severity and comorbidities. A holistic management approach that includes comorbidity management and patient education is needed to improve prognosis and quality of life. Further research is needed to explore the relationship between therapy and clinical outcomes.
Co-Authors Jubilette Windy Hutabarat Nuryunita Nainggolan Pandiaman Pandia Rizki Rahmadani Dalimunthe Tarigan, Amira Permatasari