Claim Missing Document
Check
Articles

Found 18 Documents
Search

The Relationship Between Level of Transforming Growth Factor - β with Pulmonary Fibrosis in Post Pulmonary Tuberculosis in Medan Christine, Tamara; Tarigan, Amira Permatasari; Nainggolan, Nuryunita; Zaluchu, Fotarisman
Jurnal Respirologi Indonesia Vol 40, No 1 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i1.90

Abstract

Background: Untreated or undertreated, pulmonary tuberculosis could cause severe complications until death. After treatment, residual lesions might occur. The presence of residual lesions is varied, including: fibrosis, cavity, bronchiectasis and calcification. Transforming growth factor-β (TGF-β) is a cytokine associated with lung inflammation, which plays a role in lung fibrosis. However, only a few studies have assessed the serum level of TGF-β in post-treatment tuberculosis patients. The main objective of this study was to determine the relationship between TGF-β levels and pulmonary fibrosis in patients with pulmonary tuberculosis. Methods: Among 51 patients that had undergone anti-tuberculosis treatment were observed, consisting of 31 men, 20 women. Of all patients, there were 26 people with a smoking history, including 25 men and 1 woman. All patients had been recovered, confirmed by clinical state, laboratory and radiology examination. The ELISA test was performed to measure TGF-β level, while chest X-ray was used to evaluate for the occurence of pulmonary fibrosis. Results: The mean level of TGF-β in patients with lesion (+) was 7628.02 pg/mL (SD: ±4928.38) while the mean level of TGF-β in patients with lesion (-) was 2315.11 pg/mL (SD: ±505.83). Statistical test showed a significant relationship between TGF-β level and fibrosis lesion (P
Salat Dhuha Improves Blood Pressure: A Randomized Controlled Trial Boy, Elman; Lelo, Aznan; Tarigan, Amira Permatasari; Machrina, Yetty; Yusni, Yusni; Harahap, Juliandi; Sembiring, Rosita Juwita; Syafril, Santi; Sumartiningsih, Sri
Media Ilmu Keolahragaan Indonesia Vol 11, No 2 (2021): December 2021
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/miki.v11i2.34225

Abstract

The prevalence of hypertension increases with age, more than 1 in every two elderly has hypertension, dominated by women. The primary prevention of hypertension is a worldwide public health concern. Salat dhuha is a moderate-intensity physical activity. Salat 2 movement cycles demonstrated improved systolic and diastolic blood pressure in adults. Our study purpose was to assess the effect of 2 and 8 movement cycles (rakaat) of salat dhuha to improve systolic and diastolic blood pressure in healthy Muslim elderly women. Muslim elderly women in a government senior residence (aged 60-74 years) participated in a 6 weeks controlled trial. We completed formal physical, clinical, and blood assessments before admission. Participants with hypertension history were excluded. The participants were randomized into 2 groups. The intervention group performed 8 rakaat of salat dhuha (n=13) and the control group performed 2 rakaat of salat dhuha (n=13). Two participants were dropped out of this study. At baseline and at the end of 6 weeks, a blood pressure examination is recorded. Parametric and nonparametric methods were used to analyze the data. The baseline characteristics of the two groups of participants were homogeneous. Compared to the control, the 8 rakaat of salat dhuha achieved a significant reduction in systolic and diastolic blood pressure (P0.05) at the end of the 6-weeks period. The findings show that salat dhuha has significant potential to improve blood pressure.
PENINGKATAN AMBILAN OKSIGEN MAKSIMAL (VO2 MAKS) DAN FAT FREE MASS (FFM) PADA PASIEN PENYAKIT PARU OBSTRUKSI KRONIS STABIL YANG MELAKUKAN OLAHRAGA Tarigan, Amira Permatasari; Miranda, Melly; Pandia, Pandiaman; Zulkarnain, Zulkarnain; Maryaningsih, Maryaningsih; Vera, Yeni; Zaluchu, Fotarisman
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan Vol 7, No 2: Oktober 2023
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/so.v7i2.49725

Abstract

Pasien PPOK yang mengalami atrofi dan disfungsi otot akan mengurangi pengambilan oksigen maksimal (VO2 maks) dalam jaringan. Berat badan dan penipisan massa bebas lemak (fat free mass) adalah masalah umum pada pasien PPOK dan terkait dengan kelemahan otot dan intoleransi latihan, kedua hal ini akan menyebabkan penurunan aktivitas dan kualitas hidup. Olahraga (latihan fisik) pada pasien PPOK memberikan efek yang baik terhadap toleransi latihan dan kualitas hidup. Tujuan dari penelitian ini adalah untuk menilai peran olahraga terhadap VO2 maks dan fat free mass pada pasien PPOK. Desain penelitian ini adalah eksperimental, dilakukan pada 20 pasien PPOK. Pasien melakukan latihan tubuh bagian atas dan bawah dengan latihan otot pernapasan dan sepeda statis, dua kali seminggu selama 4 minggu, mulai dari 5-20 menit/sesi. Pengukuran VO2 maks dihitung sebelum dan sesudah intervensi menggunakan Nury’s Formula® yang dirancang khusus untuk orang Indonesia (r = 0,68; p < 0,005), dengan mengkonversi jarak berjalan 6 menit. Fat free mass diukur dengan BIA (Bio Impendances analysis) pre dan pasca intervensi dan indeks massa bebas lemak dihitung sebagai FFM kg/m2. Analisis statistik dilakukan oleh T Test. Terdapat peningkatan VO2 maks diperoleh dengan tes berjalan 6 menit, dari rerata 9.24 menjadi 9.44 tetapi tidak signifikan secara statistik (p = 0,066). Pada FFM ada peningkatan tetapi tidak signifikan secara statistik pada indeks massa bebas lemak dari rerata 18.37 menjadi 18.44 (p < 0,689) setelah intervensi. Kejadian eksaserbasi tidak ditemukan ketika intervensi dilakukan. Latihan tubuh dapat meningkatkan VO2 maks dan fat free mass tetapi tidak signifikan secara statistik.Kata Kunci: Latihan tubuh, Formula Nury®, PPOK, VO2 maks, FFM
Hubungan Self-Efficacy dan Kepatuhan Pengobatan terhadap Asthma Control Test pada Pasien Asma Girsang, Isah Masdiana; Suza, Dewi Elizadiani; Tarigan, Amira Permatasari
Journal of Telenursing (JOTING) Vol 6 No 1 (2024): Journal of Telenursing (JOTING)
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/joting.v6i1.9118

Abstract

This research aims to examine the relationship between self-efficacy and treatment compliance with the asthma control test in asthma patients. This type of research is quantitative using descriptive correlational methods. The number of samples in this study that met the inclusion criteria was 44 patients at the North Sumatra University Hospital, Medan, with the sampling technique used was consecutive sampling. The instruments used in this research were self-efficacy instruments, medication adherence instruments namely MMAS-8 and Asthma control test measurements by (ACT) by the American Lung Association (ALA) questionnaire. Data analysis in this research consists of Univariate analysis and Bivariate analysis using the Chi-Square statistical test. The research results showed that self-efficacy and the Asthma Control Test (ACT) obtained a value of p = 0.01 < 0.05 and the value of treatment compliance with the Asthma Control Test (ACT) obtained a value of p = 0.051 < 0.05. In conclusion, there is no significant relationship between self-efficacy and treatment compliance with the Asthma Control Test (ACT) in asthma patients. Keywords: Asthma Control Test, Treatment Compliance, Self-Efficacy.
Pengalaman Masyarakat Aceh Selatan Terkait Perilaku Kesehatan Selama Pandemi COVID-19 Kawati, Salma Merda; Suza, Dewi Elizadiani; Tarigan, Amira Permatasari
Journal of Telenursing (JOTING) Vol 6 No 2 (2024): Journal of Telenursing (JOTING)
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/joting.v6i2.12021

Abstract

This study aims to explore in depth the experiences of the people of South Aceh related to health behavior during the COVID-19 pandemic. The research method uses a descriptive phenomenological approach with an in-depth interview process, making interview transcripts and then analyzing the data using the Collaizi analysis method. The study results showed four themes: community efforts to prevent COVID-19, psychological disorders, activities carried out during the COVID-19 pandemic, and difficulties in implementing COVID-19 prevention efforts. The conclusion is that most of the community's behavior is positive, and the community has implemented prevention efforts well, even though some religious and traditional events have been carried out during the COVID-19 pandemic. Keywords: COVID-19, Community, Experience, Health Behavior
Survival Rate of Chronic Obstructive Pulmonary Disease Patients with Type II Respiratory Failure at Haji Adam Malik Hospital Nahrisyah, Putri; Syahrani, Fajrinur; Tarigan, Amira Permatasari; Ashar, Taufik
Journal of Society Medicine Vol. 3 No. 8 (2024): August
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i8.161

Abstract

Introduction: Chronic obstructive pulmonary disease is associated with acute exacerbations that can lead to respiratory failure and as major cause of morbidity and mortality worldwide. The Aim of study was to explore survival rate of COPD patients with type II respiratory failure Methods: Observational research with retrospective cohort design using data from medical records of chronic obstructive pulmonary disease patients with type II respiratory failure treated at H. Adam Malik General Hospital Medan for 10 months from November 2021 to September 2022. Analyzed of independent and dependent variables used Chi Square test. To obtain most dominant independent variable that influence dependent variable, a multiple logistic regression test is used. Results: There were 21 patients (50%) who alived until end of research but also 21 deaths occured. Survival rate was 50% with a median survival time 14 days (CI 95%: 7.178-20.822 days). Survival rate of COPD patients with type II respiratory failure who do not routinely received therapy was 16.7% with a median survival time 4 days (CI 95%: 42.962-5.039). Survival rate of COPD patients with type II respiratory failure who routinely received therapy was 75%. Based on log rank test, there was a significant difference median length of life between patients who did not and who routinely received therapy (p <0.001). Conclusion: The survival rate in COPD patients who regularly use inhaler therapy is significantly higher than patients who do not routinely use inhaler therapy.
Anxiety Levels of Severe COVID-19 Patients at Haji Adam Malik Hospital Medan in 2022 Nurul Citta Banu Putri; Tarigan, Amira Permatasari; Pendiaman Pandia; Andika Pradana; Putri Chairani Eyanoer; Elmeida Effendy
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 2 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i2.11941

Abstract

Background: The COVID-19 pandemic is affecting the healthcare system and causing psychological changes, not only among healthcare professionals but also among citizens. These psychological changes are caused by depression, fear, anxiety, or insecurity. This study aims to investigate the anxiety level of severe COVID-19 patients who were treated at Haji Adam Malik General Hospital Medan in 2022 Method: This research is a descriptive observational study at the Department of Pulmonology and Respiratory Medicine Haji Adam Malik Hospital Medan from January 2022 until several samples were fulfilled. Sampling was done by consecutive sampling technique by filling Google Form questionnaire. The Hospital Anxiety and Depression Scale (HADS) questionnaire consists of seven items which can breakdown into anxiety subscales. The detail scores for every item ranged from zero to three. Score three indicated the highest level of anxiety. A total subscale score of >8 points out of 21 indicates significant anxiety symptoms. Data were analyzed descriptively to find out the frequency distribution of research subjects based on research sample characteristics. Results: From 36 research samples, 23 samples (63.9%) were male, and 13 samples (36.1%) were female. On anxiety levels, it was found that HADS-A scores were severe in  21 patients with severe COVID-19 (58.3%) and moderate levels in 15 patients (41.7%) with severe anxiety levels. Conclusion: Anxiety levels appear to be significantly increased in patients with severe COVID-19
Relationship between LDH Levels with COVID-19 Degree of Severity Tambunan, Adrian Nurrachman; Ganie, Ratna Akbari; Tarigan, Amira Permatasari
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 4 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i4.14414

Abstract

Background: LDH has proved to be a significant predictor for prognosis and follow-up in COVID-19 patients. Several studies report elevated LDH in hospitalized COVID-19 patients to be associated with a higher risk of death. Increased LDH levels can result from any tissue damage due to SARS-CoV-2 infection. The study aims to describe the relationship between LDH levels with COVID-19 19 degree of severity. Methods: This study is a cross-sectional study of 55 patients who confirmed positive by RT-PCR SARS-CoV-2 at H. Adam Malik General Hospital Medan (November 2021 – Maret 2022). Examination of the LDH level was carried out by the Chemiluminescent Immunoassays method (Abbott Architect). COVID-19 degree of severity was assessed based on the diagnostic criteria for COVID-19 cases in Indonesia. Results: Among the 55 COVID-19 patients in this study, the average age found was 45.73, with men 54.5%. Moderate, severe, and critical patients were found in 63.6%; 29.1%; and 7.3% respectively. The mean LDH level at admission was 278 U/L, higher in the severe (333.19 U/L) and critical (465.75 U/L) groups compared to the moderate (231.31 U/L) groups. Increased LDH ≥ 256 U/L proved to be related to COVID-19 degree of severity upon hospital admission (CI 95%; p = 0.001). Conclusions: LDH levels that increased ≥ 256 U/L were significantly related to COVID-19 degree of severity during hospital admission.
The Relationship between Malnutrition and Quality of Life in Stable Chronic Obstructive Pulmonary Disease Patients at Prof. Dr. Chairuddin P. Lubis Hospital Field Dalimunthe, Muhammad Bayhaqi; Pradana, Andika; Tarigan, Amira Permatasari; Amelia, Rina
Journal of Society Medicine Vol. 3 No. 9 (2024): September
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i9.164

Abstract

Introduction: Malnutrition is a serious problem in patients with COPD, it interferes with normal skeletal muscle function, with reduced muscle mass and decreased respiratory muscle strength and endurance. It also contributes to respiratory muscle dysfunction, disease severity, and disability progression. Malnutrition is associated with disease severity, associated with more severe exacerbations, and increases the length of hospital stay. Malnutrition in COPD is described with varying prevalence rates ranging from 30-60%. The aim of this study was to analyse the relationship between malnutrition and quality of life in patients with COPD. Method: The research design is an observational analytic conducted from November 2023 to March 2024. The study population was COPD patients who sought treatment at the Pulmonary Polyclinic at RSCPL with a total sample using the consecutive sampling method of 91 people. Manultrition assessment by measuring TB and BW of patients when they arrived and assessing quality of life with the SGRQ questionnaire, Data processing using SPSS by correlating malnutrition with quality of life, degree of shortness of breath, and spirometry. Results: There was a significant positive correlation between malnutrition and quality of life (p=0.001) with the degree of shortness of breath (p=0.014) and spirometry (p=0.001). Conclusion: We found an association between malnutrition and quality of life, degree of breathlessness and spirometry of patients with COPD, further prospective studies in other populations are needed to validate the results of this study.
The Effect of Providing Education on the Use of Inhalers on Asthma Degrees Based on the Asthma Control Test (ACT) in Patients at Tanjungpura Hospital Bayani, Sri; Tarigan, Amira Permatasari; Pandia, Pandiaman; Amelia, Rina; Jefri, Budi
Journal of Society Medicine Vol. 3 No. 10 (2024): Oktober
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i10.168

Abstract

Introduction: The main goal of asthma treatment is to control symptoms and reduce emergency department (ED) visits due to acute exacerbations. Drug delivery through inhalation is an important component of asthma management. Patients with asthma should have a good knowledge of their disease to recognize signs of worsening that can be prevented by early detection. Asthma control can be evaluated using the Asthma Control Test (ACT). To determine the effect of providing education on the use of inhalers on the degree of asthma based on the ACT in patients at Tanjungpura Regional General Hospital. Methods: This quasi-experimental study conducted from March 2024 to May 2024, used a one-group pre-test and post-test design to evaluate the effect of education via smartphone applications on asthma control (ACT). Obtained 54 patients who were diagnosed asthma at Tanjungpura Regional General Hospital. The sample consisted of asthma patients using inhalers, selected consecutively based on inclusion and exclusion criteria. Results: Most patients were female (64.8%) with ages 18-60 years (83.3%). The majority were housewives (46.2%). Post-test showed that 75.9% of patients had partial asthma control. All patients (100%) used inhalers correctly after education. There was a significant difference in ACT results before and after education (P-value 0.001) and an increase in ACT scores after the first and second education (P-value 0.002 and 0.001, respectively). Conclusion: Providing education on the use of inhalers has a positive effect on ACT scores in asthma patients, with an increase in the mean ACT score from 15.67 before education to 17.11 after the first education, and 20.96 after the second education.