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All Journal The Indonesian Biomedical Journal ACI (Acta Cardiologia Indonesiana) Heart Science Journal Brawijaya Journal of Urology
Ardian Rizal
Department Of Cardiology And Vascular Medicine, Faculty Of Medicine, Universitas Brawijaya
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Symptomatic Bradycardia In CAD Patient: Which One First To Treat? Aloysius Yuwono Suprapta; Mohammad Saifur Rohman; Ardian Rizal; Sasmojo Widito
Heart Science Journal Vol 3, No 4 (2022): Prevention, Screening dan Rehabilitation : The Back Bone of Quality Care Improve
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2022.003.04.6

Abstract

Background: The incidence of sinus node dysfunction (SND) increases with age. Likewise, the incidence of coronary artery disease (CAD) has increased from year to year in Indonesia. When doctors are faced SND patients with CAD, it can be confusing in determining initial treatment options.Objective: This study aimed to describe the diagnosis and management of SND in CAD patient.Case Presentation: We will discuss a 75 years old male who had schedule to management of bradycardia symptomatic related to SND. Five month before admission, he had acute coronary syndrome, and had 2 DES implantation at left main (LM) to proximal left anterior descendent (LAD) artery and mid LAD. Two month after PCI he felt near syncope with bradycardia. Evaluation with ambulatory EKG was performed with result of SND, and correction of reversible cause related to SND already done. Eventually, symptom still exist and PPM insertion was decided to perform.Conclusion: Patients with SND and CAD have a higher risk of complications and death. Correction of reversible factors, one of which is CAD, can be done as an initial step in the treatment of SND. When symptomatic signs still appear after correction of reversible causes, PPM implantation is the modality of choice in management.
Perioperative Myocardial Infarction After Coronary Artery Bypass Grafting: How to Identify? Diah Ivana Sari; Setyasih Anjarwani; Ardian Rizal
Heart Science Journal Vol 4, No 1 (2023): Optimizing Outcome in Acute Cardiac Care
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.01.6

Abstract

Introduction. Perioperative myocardial infarction (PMI) associated with the surgical revascularization (CABG) occurs in about 3–5% of patients. Myocardial necrosis and ischaemia after CABG are caused by direct cardiac trauma from manipulation, reperfusion injury, incomplete revascularization, hypotension, bleeding, ventricular arrhythmia, acute graft closure, inadequate perioperative myocardial protection and others.Case report. The introduced case report explains the rupture of right ventricle result in periprocedural myocardial infarction following the surgical myocardial revascularization. 62-year-old man has undergone the coronary bypass surgery with arterial graft of left mammary artery (LIMA) to left anterior descending artery (LAD) and savenous graft to left circumflex coronary artery (LCx). Early in the post-surgery period a perioperative myocardial infarction (PMI) developed, with laboratory correlation of cardio-specific enzymes elevation and ECG changes in terms of ischaemia in the diaphragmatic region. Echocardiography showed akinesia of the apex, apical septal and apical inferior segments accompanied by the decrease in ejection fraction (EF) of the left ventricle.Conclusion. Early detection of PMI may therefore, prompt institution of therapeutic measures to relieve the ischaemia and decrease the incidence and the size of PMIKey words: Perioperative Myocardial Infarction, CABG
Ganoderma lucidum Polysaccharide Peptide Reduces Oxidative Stress and Improves Renal Function in Patient with Cardiometabolic Syndrome Syanindita Puspa Wardhani; Khilmi Ainun Nadliroh; Al Mazida Fauzil Aishaqeena; Fahriza Abid Sonia; Achmad Guntur Hermawan Suryo Adji; Intan Masyfufah Hanim; Rizkia Milladina Hidayatulloh; Anna Fuji Rahimah; Ardian Rizal; Peter Sugita; Ferry Sandra; Djanggan Sargowo
The Indonesian Biomedical Journal Vol 15, No 2 (2023)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v15i2.2137

Abstract

BACKGROUND: Cardiometabolic syndrome is a risk factor for the development of diseases related to cardiovascular disease and decreased renal function. Ganoderma lucidum polysaccharide peptide (GLPP) has been reported to have anti-inflammatory and antioxidant properties. The current study was conducted to investigate the role of GLPP in inflammatory, oxidative stress and renal function markers of cardiometabolic subjects.METHODS: A randomized double-blinded perspective control trial with pre-post design was conducted. Cardiometabolic syndrome subjects were treated with placebo or GLPP for 60 days. Blood serum was collected from each subject before the first capsule consumption and one day after the last capsule consumption. Serum tumor necrosis factor (TNF)-α, high-sensitivity-C-Reactive Protein (hs-CRP) and malondialdehyde (MDA) levels were measured using enzyme-linked immunosorbent assay, while superoxide dismutase (SOD) level was measured using colorimetric assay. Serum urea and creatinine levels were measured using a clinical analyzer. The Cockroft-Gault formula was used to calculate estimated glomerular filtration rate (eGFR).RESULTS: Compared with the control group, the MDA level was significantly reduced, while the SOD level was significantly increased in the GLPP treatment group. Furthermore, serum urea and creatinine were lowered, while eGFR was increased in the GLPP treatment group.CONCLUSION: Treatment of GLPP for 60 days could be beneficial for lowering oxidative stress and improving renal function of patients with cardiometabolic syndrome.KEYWORDS: Ganoderma lucidum, cardiometabolic syndrome, inflammation, oxidative stress, renal function
Relationship Between Benign Prostatic Hyperplasia and Metabolic Syndrome Taufiq Nur Budaya; Ardian Rizal; Hafizh Ananda Wibowo; Fauzan Kurniawan Dhani
Brawijaya Journal of Urology Vol. 5 No. 01 (2024): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2024.005.01.3

Abstract

Introduction. Benign Prostatic Hyperplasia (BPH) is a medical condition where there is an excessive growth of smooth muscle and epithelial cells in the prostate gland. BPH is typically seen in older men and is non-cancerous. It is estimated that around 50% of men aged 60 or above worldwide are affected by BPH. Some research has looked into the factors that may increase the risk of BPH, and one theory suggests a possible connection between metabolic syndrome and the development of BPH. This study aims to investigate the potential relationship between metabolic syndrome and the development of BPH.Methods. This study is an analytical observational research conducted at Saiful Anwar Hospital in Malang from 2015 to 2020, employing a case-control research design. The data used for this study are secondary data extracted from medical records. The data analysis involved the application of both Chi-Square and Logistic Regression methods.Results. The study gathered data from 90 patients, and the analysis revealed that the highest number of BPH patients fell into the category of those with hypertension, totaling 34 individuals (75.56%). Among the factors considered, including fasting blood glucose, body mass index, and metabolic syndrome, the chi-square test indicated that body mass index and blood pressure were significantly associated with BPH, both yielding p-values of 0.046; OR (95%Cl) = 2.473 (1.006 – 6.075). Furthermore, in the logistic regression test, it was determined that fasting blood glucose, blood pressure, and body mass index categories had a significant impact on BPH.Conclusions. This research illustrates that there is an association between type 2 diabetes, hypertension, and obesity with the occurrence of BPH. However, there is no statistically significant relationship between the components of metabolic syndrome and the occurrence of BPH.
Co-Authors Achmad Guntur Hermawan Suryo Adji Adhika Prastya Wikananda Aditha Satria Maulana Adriyawan Widya Nugraha Al Mazida Fauzil Aishaqeena Aloysius Yuwono Suprapta Anjarwani, Setyasih Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Aris Munandar ZI Aris Munandar Zulkifli Ismail Budi Satrijo Bunga Bella Pratiwi Cholid Tri Tjahjono Cik Kahadi Diah Ivana Sari Djanggan Sargowo Djanggan Sargowo Djanggan Sargowo Djanggan Sargowo Djanggan Sargowo Fahmy Rusnanta Fahmy Rusnanta Fahriza Abid Sonia Fajar, Jonny Karunia Faris Wahyu Nugroho Fauzan Kurniawan Dhani Ferry Sandra Fitranti Suciati Laitupa Hafizh Ananda Wibowo Harris Kristanto Heny Martini Icmi Dian Rochmawati Indra Prasetya Indra Prasetya Intan Masyfufah Hanim Khilmi Ainun Nadliroh Mohammad Rizki Fadlan Mohammad Saifur Rohman Mohammad Saifur Rohman Muhamad Rizki Fadlan Muhammad Saifur Rohman Novi Kurnianingsih Olivia Handayani Olivia Handayani Peter Sugita Puspa Lestari Putri Annisa Kamila Putri Annisa Kamila Rizkia Milladina Hidayatulloh Sasmojo Widito Sasmojo Widito Seprian Widasmara Setyasih Anjarwani Susanti Lara Dewi Syanindita Puspa Wardhani Taufieq Ridlo Makhmud Taufiq Nur Budaya Tonny Adriyanto Veny Kurniawati Wiwit Nurwidyaningtyas Yoga Waranugraha Yuke Fawziah Kemala