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All Journal Sport and Fitness Journal METAMORFOSA Journal of Biological Sciences INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES E-Jurnal Medika Udayana JURNAL BIOMEDIK Public Health of Indonesia ISM (Intisari Sains Medis) : Jurnal Kedokteran Neurologico Spinale Medico Chirurgico IJAAM (Indonesian Journal of Anti-Aging Medicine) Jurnal Ilmiah Sangkareang Mataram Public Health and Preventive Medicine Archive Journal of Global Pharma Technology
Gde Ngurah Idraguna Pinatih
Bagian Ilmu Kedokteran Komunitas/Ilmu Kedokteran Pencegahan Fakultas Kedokteran Universitas Udayana
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Journal : JURNAL BIOMEDIK

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Pemberian suplemen Swissoats A3® meningkatkan kadar hormon estrogen pada tikus (Rattus norvegicus) betina menopause galur Wistar Widhayanthi, Trisna A.; Pangkahila, Wimpie; Pinatih, Gde Ngurah Indraguna
Jurnal Biomedik : JBM Vol 9, No 2 (2017): JURNAL BIOMEDIK : JBM
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.9.2.2017.16354

Abstract

Abstract: Aging is a physiological process that occurs in all living creatures. Swissoats A3® is an anti-aging supplement that contains phytoestrogens. This study was aimed to prove that Swiss oats A3® supplementation could increase estrogen levels in menopausal female Wistar rats (Rattus norvegicus). This was an experimental study with a completely randomized pretest-posttest control group design. Subjects were 20 menopausal female rats (Rattus norvegicus), Wistar strain, healthy, aged 15-16 months, weighing 200 g, divided into 2 groups: the control group (P0), treated with distilled water for 21 days and the treatment group (P1), treated with Swissoats A3® of 34.2 mg/rat/day for 21 days. Before and after 21 days of treatment, 1 ml venous blood was drawn through the medial canthus of orbital sinus using microcapillary tube and the estrogen levels were meassured by using indirect ELISA method. The results showed that before treatment, the mean estrogen level in P0 group was 14.96±2.0468 pg/ml and in P1 group was 14.21±2.3905 pg/ml (P > 0.05). Meanwhile, after 21-day treatment, the mean estrogen level in P0 group was 15.07±1.8851 pg/ml, whereas in P1 group was 28.33±3.2052 pg/ml (P < 0.01). The analysis showed that the Swissoats A3® could elevate the estrogen levels significantly (P < 0.01) in group P1 (2.3905±14.21 vs 28.33±3.205). Conclusion: Swissoats A3® supplementation could increase the estrogen levels in menopausal female Wistar rats (Rattus norvegicus).Keywords: Swiss oats A3®, estrogen, female Wistar rats, menopauseAbstrak: Penuaan (aging) merupakan suatu proses fisiologik yang dialami oleh seluruh mahluk hidup. Swissoats A3® merupakan suplemen anti-aging yang mengandung fitoestrogen. Penelitian ini bertujuan untuk membuktikan bahwa pemberian suplemen Swissoats A3® dapat meningkatkan kadar estrogen pada tikus (Rattus norvegicus) betina menopause galur Wistar. Jenis penelitian ialah eksperimental dengan randomized pretest-posttest control group design. Subjek penelitian ialah 20 ekor tikus putih betina (Rattus norvegicus) galur Wistar, sehat, menopause, umur 15-16 bulan, berat badan 200 gr. Tikus dibagi menjadi 2 kelompok yaitu kelompok kontrol (P0) yang diberikan aquadest secara sonde selama 21 hari dan kelompok perlakuan yang diberikan suplemen Swissoats A3® dosis 34,2mg/ekor/hari secara sonde selama 21 hari. Sebelum dan sesudah 21 hari perlakuan, darah vena diambil melalui medial canthus sinus orbitalis sekitar 1 ml dengan menggunakan tabung mikrokapiler dan dilakukan pemeriksaan kadar estrogen menggunakan metode indirect ELISA. Hasil penelitian menunjukkan bahwa sebelum perlakuan, rerata kadar estrogen kelompok P0 14,96±2,0468 pg/ml dan kelompok P1 14,21±2,3905 pg/ml (P > 0,05). Setelah perlakuan selama 21 hari, rerata kadar estrogen kelompok P0 15,07±1,8851 pg/ml dan kelompok P1 28,33±3,2052 pg/ml (P < 0,01). Analisis efek perlakuan menunjukkan terjadinya peningkatan kadar hormon estrogen yang sangat bermakna (P < 0,01) pada kelompok P1 (14,21±2,3905 vs 28,33±3,205). Simpulan: Swissoats A3® dapat meningkatkan kadar estrogen pada tikus (Rattus norvegicus) betina menopause galur wistar.Kata kunci: Swissoats A3®, estrogen, tikus wistar betina, menopause
HUBUNGAN PEMBERIAN ASI EKSKLUSIF TERHADAP KEJADIAN DIARE PADA BAYI USIA 6-12 BULAN DI PUSKESMAS DENPASAR BARAT II P., Gede Odi Bayu D.; Duarsa, Dyah P.; Pinatih, Gde Ngurah I.; Ariastuti, Luh P.
JURNAL BIOMEDIK : JBM Vol 12, No 1 (2020): JURNAL BIOMEDIK : JBM
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.12.1.2020.27714

Abstract

Abstract: Diarrhea is the leading cause of death and morbidity among infants in developing countries. This disease can be triggered by various factors, one of them is unprovided exclusive breastfeeding. Infants who were given exclusive breastfeeding until the age of 6 months had fewer digestive and growth problems. This study was aimed to determine the relationship between exclusive breastfeeding and the incidence of diarrhea among infants aged 6-12 months at West Denpasar II Public Health Center. This was an analytical study with a cross sectional design. Respondents were 84 mothers of infants selected by using purposive sampling technique. Data of this study were obtained by using the Likert scale questionnaire. The Pearson correlation test showed a negative correlation between exclusive breast feeding and the occurrence of diarrhea (r=-0.646 and p=0.000) and a positive correlation between partial breastfeeding and the occurrence of diarrhea (r=0.731 and p=0.000). In conclusion, there was a significant relationship between exclusive breastfeeding and the occurrence of diarrhea. The more the exclusive breast feeding the lower the occurrence of diarrhea. It is suggested to socialized the benefit of exclusive breastfeeding to nursing mother and mother to be, therefore, prevention of infant diarrhea can be achieved.Keywords: infants, diarrhea, exclusive breastfeeding Abstrak: Diare merupakan penyebab utama terjadinya mortalitas dan morbiditas pada bayi di negara berkembang. Diare dapat dipicu oleh berbagai faktor, salah satunya ialah tidak dilakukannya pemberian ASI eksklusif. Bayi yang diberikan ASI eksklusif sampai usia 6 bulan lebih sedikit mengalami gangguan gastrointestinal dan gangguan pertumbuhan. Penelitian ini bertujuan untuk mengetahui adanya hubungan antara pemberian ASI eksklusif dengan angka kejadian diare pada bayi usia 6-12 bulan di Puskesmas Denpasar Barat II. Jenis penelitian ialah analitik dengan desain potong lintang. Responden berjumlah 84 ibu dari bayi yang dipilih dengan teknik purposive sampling. Pengumpulan data yang digunakan ialah melalui kuesioner dengan skala Likert. Uji korelasi Pearson menunjukkan hubungan negatif antara pemberian ASI eksklusif dan kejadian diare (r=-0,646 dan p=0.000) serta hubungan positif antara pemberian ASI parsial dengan kejadian diare (r=0,731 dan p=0,000). Simpulan penelitian ini ialah terdapat hubungan bermakna antara pemberian ASI eksklusif dengan kejadian diare. Semakin meningkatnya pemberian ASI eksklusif maka kejadian diare akan menurun. Disarankan untuk meningkatkan sosialisasi masalah pemberian ASI eksklusif kepada ibu menyusui ataupun calon ibu menyusui agar dapat meningkatkan kesehatan bayi khususnya terhindar dari penyakit diare.Kata kunci: bayi, diare, pemberian asi eksklus
Co-Authors A. A. G. P. Wiraguna A. Santosa Adiputra, I Made Sudarma Anak Agung Ayu Ngurah Susraini Anak Agung Gde Putra Wiraguna Anak Agung Gde Putra Wiraguna Anak Agung Mas Putrawati Triningrat Ariastuti, Luh P. Ariesanti Tri Handayani, Ariesanti Tri Azri Hazwan Bunge Dianmentari Citra Anggraeny Devita Horax Dhumaranang, Hyangayu Dedari Dyah Pradnyaparmita Duarsa Fanny Rustandi Felicia Hartono Felix Kusmana Gede Putra IGN Gian Lisuari Adityasiwi Gina Septivani H Da Silva Hayatul Firi Herman Saputra I Dewa Nyoman Wibawa I Gede Widyatmika Pratama I Gusti Agung Triana Suharidewi I Gusti Ayu Sri Mahendra Dewi I Gusti Made Aman I Made Krisna Dinata I MADE MULIARTA . I Made Suganda Yatra I MADE SUTARGA I Putu Adiartha Griadhi I Putu Gede Adiatmika I Wayan Gede Artawan Eka Putra I Wayan Gede Jayanegara I Wayan Weta Ida Ayu Eugenia Natasha Blanco Oka Ida Bagus Ngurah IKG Muliartha Imtihanatun Najahah Jaeynisha Mathavan Kadek Tresna Adhi Ken Andrina Anindita Ketut Pramana Adiputra Ketut Tirtayasa Luh Made Indah Sri Handari Adiputra Luh Seri Ani Made Agus Kusumadjaja Makbullah - Marthin Alexander Rocky Muh. Irfan Muhammad Syairozi Hidayat Mulyanto Munawwarah, Muthiah Ni Made Ari Sukmandari Ni Made Septiari Maryani Ardi Ni Wayan Septarini Ni Wayan Trisnadewi, Ni Wayan NT Suryadhi Ompusunggu, Hillary Sekarningrum P., Gede Odi Bayu D. Pande Made Respa Dharma Syantih Pande Putu Januraga Pradnyaparamita, Dyah Putu Adhi Surya Pradana Rubagan Chelvam Samantha Celena Triadi Sawitri, Anak Agung Sagung Sriwiyanti Sriwiyanti Susy Purnawati Thivyadharshini Uvaraju Triyanto Nugroho Wahyuddin, Wahyuddin Widhayanthi, Trisna A. Wimpie I Pangkahila