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All Journal Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Media Farmasi Journal of Pharmaceutical and Medicinal Sciences Pharmacoscript Jurnal farmasi UIN Alauddin Makassar Journal of Pharmaceutical and Health Research Jurnal Kesehatan Tambusai Dikmas: Jurnal Pendidikan Masyarakat dan Pengabdian Pharmaceutical Reports
Hamsinah Hamsinah
3Fakultas Farmasi, Universitas Muslim Indonesia, Makassar, Sulawesi Selatan
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Jurnal farmasi UIN Alauddin Makassar

 1 
Formulasi dan Evaluasi Granul Gastroretentive Mukoadhesif Amoksisilin Hamsinah Hamsinah; Jufri Jufri; Ermina Pakki
Jurnal Farmasi UIN Alauddin Makassar Vol 4 No 3 (2016): Jurnal Farmasi
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v4i3.2228

Abstract

Amoxicillin is a semisynthetic antibiotic, belonging to the β-Lactam family, which is effective for bacterial infection treatment, especially for Helicobacter pylori infection. In this research, Amoxicillin was formulated as mucoadhesive granules dosage form to improve their effectivenesses by increasing the residence time of dosage form in the stomach. Mucoadhesive granules were prepared by wet granulation method in ten formulas using HidroxypropylMethyl cellulose, Methyl cellulose and Ethyl cellulose as mucoadhesive polymers. Granules were evaluated for moisture content, flow rate, angle of repose, density, mucoadhesive strength with wash off test, and dissolution.The results of this researchshowed that formula IB with 50% HPMC has best mucoadhesive strength with percentage of mucoadhesion 20% in 90 minutes of wash off test, and also formula IB is slowest formula in releasing of drug, with percentage of drug released is 55,76% in 15 minutes and 104,01% in 180 minutes.
PEMANFAATAN EKSTRAK ETANOL KULIT RAMBUTAN (Nephelium lappaceum. L) SEBAGAI KRIM ANTIOKSIDAN Hamsinah Hasan; M Ilham Tomagola; Suci Mayasari
Jurnal Farmasi UIN Alauddin Makassar Vol 6 No 1 (2018): Jurnal Farmasi
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v6i1.5267

Abstract

The rind of Rambutan was consumed by citizen just becomes waste.  Rambutan with Latin Nephelium lappaceum. L of the Sapindaceae tribe of the skin can be used as an antioxidant that has been stained by Thitilertdecha, et al mention that the phenolic component of the skin of rambutan fruit (Nephelium lappaceum L), among others, is geranin and corilagin is a group of flavonoids, and alegat acid from tannins class. Based on this, we will conduct research and formulate rambutan rind extract into cream preparations that have an antioxidant effect. The rambutan rind extract was obtained by using maseration method with 70% ethanolic and the viscous extract followed by testing of antioxidant activity by using DPPH method, obtained by IC50 22.774 μg / mL. The formula is varied with three emulgators. Formula I uses 2% TEA emulgator, Formula II Tween 80 and Span 80 3%, and 1% sodium lauryl sulphate. This antioxidant cream formula is physically tested for stability, including organoleptic test, emulsion type, pH measurement, viscosity measurement, forced conditions, homogeneity and flow type. Then proceed with testing the emulsion type of the cream preparation. The creamy formula of rambutan skin ethanol extract with a pharmaceutically stable 1% sodium lauryl sulfate emulgator
Co-Authors Adinda Dwi Ayu D Rasyid Aminah Aminah Anifatul Mu’awanah Asriani Suhaenah Ermina Pakki Inayanti Fatwa Jufri Jufri M Ilham Tomagola M Vina Purnamasari Meylinda Amelia Mulyana, Imam Dwiyan Nurmaya Effendi Nurmaya Effendy Nurmila A. Abiwa Rachmat Mauluddin Ririn Ririn Sasanti D. Darijanto Suci Mayasari SULASMI ANGGO Sulfiani Sulfiani Syahratul Hawaisah Yahya Vina Purnamasari M