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All Journal Current Research on Biosciences and Biotechnology
Wan Yaacob Wan Ahmad
School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43650 UKM Bangi, Selangor, Malaysia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Materials Science & Nanotechnology Medicine & Pharmacology

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Antibacterial activity of lupeol from the bark of Dehaasia cuneate (Lauraceae) Andi Rifki Rosandy; Sumail Sidik Ode Ishak; Noor Aziiraa Sabri; Wan Yaacob Wan Ahmad; Laode Muhammad Ramadhan Al Muqarrabun
Current Research on Bioscences and Biotechnology Vol. 2 No. 2 (2021)
Publisher : Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/crbb.2021.2.2/BOFY6724

Abstract

Dehaasia cuneata, locally known in Malaysia as ‘gajus hutan or pekan’, belongs to family Lauraceae. From its bark, A triterpenoid, lupeol was isolated and characterized. The chemical structure of the isolated compound was determined using spectroscopic methods, such as UV–vis, FT-IR, 1D & 2D-NMR, and ESIMS spectrometer. The isolated compound was tested against Gram-negative and positive bacteria using agar disc diffusion technique. The results showed that lupeol had a moderate inhibition zone value of 10.0±0.00 mm against Gram-negative Serratia marcescens ATCC 14756 whereas low inhibition which is 7.0±0.00 mm against Escherichia coli ATCC 25922, Vibrio fluvialis ATCC 33809, Bacillus subtilis ATCC 6633, and Methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300.
Co-Authors Andi Rifki Rosandy Laode Muhammad Ramadhan Al Muqarrabun Noor Aziiraa Sabri Sumail Sidik Ode Ishak