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Sri Hartini
Department of Pharmacology and Toxicology, Bandung Institute of Technology, Bandung, West Java, Indonesia
Medicine & Pharmacology

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Adverse Drug Reactions in Hospitalized-Geriatric Patients with Hypertension Andi I. Julianti; Lia Amalia; Sri Hartini
Pharmacology and Clinical Pharmacy Research Vol 4, No 3
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13.573 KB) | DOI: 10.15416/pcpr.v4i3.24923

Abstract

Adverse drug reactions (ADRs) occur often in geriatric patients due to various factors which include a decrease in the physiological function and organs, nutritional deficiencies, multipathology, and polypharmacy. This study aimed to identify and analyse ADRs of hospitalized-geriatric patients with hypertension. We conducted a cross-sectional retrospective study (August 2012 to January 2013). Probability determination was calculated by the Naranjo scale. The subjects on this study were hospitalized-geriatric patients (n=86, 46.51% male, and 53.48% female). Thirty-one patients (11 men and 20 women) participated in this study by completing questionnaires to calculate ADRs probability using the Naranjo scale. The probability results were 7 probable, 8 possible, and 16 doubtful. Moreover, we observed that there were drug-related problems (DRP) during therapy, e.g., appropriate dose (59.37%), and inappropriate dose 34.37%. It can be concluded that in hospitalized-geriatric patients with hypertension, some problems related to ADRs remain existed.
Co-Authors Andi I. Julianti Lia Amalia