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Alan Anderson Bangun
Faculty of Medicine, Diponegoro University, Semarang 50275, Indonesia; Dr. Sardjito General Hospital, Jalan Kesehatan No. 1, Yogyakarta 55281, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Mathematics

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Overview of Boron Neutron Capture Therapy: a Medical Aspect Alan Anderson Bangun; Bagaswoto Poedjomartono
ASEAN Journal on Science and Technology for Development Vol. 35 No. 3 (2018): Developments in Nuclear Techniques in the Treatment of Cancer
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1010.558 KB) | DOI: 10.29037/ajstd.512

Abstract

Cancer is an abnormal growth of a cell due to the cell’s inability to control and maintain its proliferation, differentiation and apoptosis cycle. There are several methods to treat cancer; one of which is boron neutron capture therapy (BNCT). BNCT is a radiation modality by which a high radiation dose is delivered to tumor cells with lower damage to surrounding normal tissue. This modality has been used widely as a treatment for several cancer cases, such as head and neck cancer, breast cancer, and liver cancer. BNCT uses sodium borocaptate (BSH) or boronophenylalanine (BPA) as the delivery agent. Then, the tumor cell is irradiated by thermal radiation. This technique has excellent potential to become a main method of cancer therapy in the future, since it is noninvasive and has fewer side effects than other methods. Further studies on BNCT are needed to improve its performance as a cancer treatment modality.
Co-Authors Bagaswoto Poedjomartono Bagaswoto Poedjomartono