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All Journal Media Farmasi Jurnal Aisyah : Jurnal Ilmu Kesehatan
Ariyani Buang
Universitas Pancasakti
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Pemanfaatan Pati Singkong Tergelatinasi Sebagai Pengikat Tablet Asetosal Yang Dibuat Dengan Metode Kempa Langsung Hesty Setiawati; Ariyani Buang; Rusli Rusli; Hendra Stevani; Ratnasari Dewi
Media Farmasi XXX Vol 16, No 2 (2020): MEDIA FARMASI
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar, Kementerian Kesehatan RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v16i2.1819

Abstract

Direct compression is the simplest and most efficient method of making tablets, but not all additives adopt this method. This research aims to analyze the ability of gelatinized cassava starch (Manihot utillissima) as an additive for the manufacture of tablets by direct compression using the acetosal active ingredient with a concentration of 100 mg. Furthermore, the cassava starch made from tubers (Manihot utillissima) is gelatinized by heating and then used as an additive in the manufacturing of acetosal tablets by direct compression. The results showed that the gelatinized cassava starch (Manihot utillissima) powder had good flow and compressibility properties and the acetosal acetosal tablets produced had good physical properties and solubility, therefore it was concluded that it is used as an additional ingredients in manufacturing acetosal tablets with direct compression methodKeywords : Gelatinized Cassava Starch (Manihot utillissima), Direct Compression, AsetosalKempa Langsung merupakan metode pembuatan tablet yang paling sederhana dan efisien, namun tidak semua bahan tambahan tablet dapat digunakan dalam metode kempa langsung. Penelitian ini bertujuan untuk menganalisis kemampuan pati singkong (Manihot utillissima) yang tergelatinasi sebagai bahan tambahan dalam pembuatan tablet secara kempa langsung dengan menggunakan bahan aktif asetosal dengan konsentrasi 100 mg. Pati singkong dari umbi singkong (Manihot utillissima) dibuat tergelatinasi dengan pemanasan lalu digunakan sebagai bahan tambahan dalam pembuatan tablet asetosal dengan metode kempa langsung. Hasil penelitian menunjukan serbuk pati singkong (Manihot utillissima) tergelatinasi memilki sifat Alir dan kompresibilitas yang baik dan tablet Asetosal asetosal yang dihasilkan memilki sifat fisik dan kelarutan yang baik, sehingga dapat disimpulkan Pati Singkong tergelatinasi dapat dimanfaatkan sebagai bahan tambahan dalam pembuatan tablet Asetosal dengan meode kempa langsungKata kunci : Pati Singkong (Manihot utillissima) tergelatinasi, Kempa Langsung, Asetosal 
Testing the larvacides activities of clove leaves extract (Syzygium aromaticum) on the mortality of Aedes Aegypti L. Ariyani Buang; Farid Fani Temarwut; Suprapto Prayitno
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 2: June 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v8i2.2048

Abstract

Dengue Hemorrhagic Fever (DHF) is an infection caused by the dengue virus which is transmitted by the Aedes Aegypti mosquito. Clove leaves (Syzigum aromaticum) is a part of a plant that contains eugenol, saponins, flavonoids and tannins which are useful as natural larvicides against Aedes Aegypti mosquito larvae.This study aims to determine the effect of larvicides Clove leaf extract (Syzigium aromaticum) on Aedes aegypti L larvae and to determine the LC50 value that can kill Aedes aegypti L larvae. This study was an experimental study with a post test only group control design. Clove leaves were extracted by maceration using 96% w/v ethanol.This study was divided into 7 groups using Aedes aegypty Instar III larvae, namely:2 control groups namely K1 NaCMC 1% as negative control and K6 Abate 0.1% b/v as positive controland 5 treatment groups each with a concentration of clove leaf extract K20.010 % w/v, K3 0.025 % w/v, K4 0.05 % b/v, K5 0.075 % b/v and K6 0.100 % b/v.The number of larvae deaths was counted after 24 hours.HThe results of the study showed that the number of deaths of Aedes aegypti mosquito larvae for each group was: K1 0%, K2 3.33%, K3 8.33%, K4 23.33%, K5 53.33%, K6 80% and K7 100 %Analysis results statistics using Anova. and the LSD follow-up test isthere was a significant difference in larval mortality at each concentration (p 0.00 less than 0.05) And K2 showed a non-significant effect with K3 (sig p 0.089 more than 0.05). From the research results it can be concluded that clove leaf extract (Syzygium aromaticum L) has a larvicidal effect on Aedes aegypti larvae. Clove leaf extract (Syzygium aromaticum) can kill Aedes aegypti mosquito larvae with an LC50 value of 600 ppm and is included in the toxic category.
Co-Authors Farid Fani Temarwut Hendra Stevani Hesty Setiawati Ratnasari Dewi Rusli Rusli Suprapto Prayitno