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All Journal Oto Rhino Laryngologica Indonesiana Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Ahmad Dahlan Medical Journal
Asti Widuri
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Pengaruh suplementasi probiotik Lactobacillus casei L shirota strain terhadap kadar IgE penderita rinitis alergi Asti Widuri; Lilis Suryani
Oto Rhino Laryngologica Indonesiana Vol 41, No 1 (2011): Volume 41, No. 1 January - June 2011
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (424.333 KB) | DOI: 10.32637/orli.v41i1.60

Abstract

Background: Allergic rhinitis is a nasal mucosal inflammatory reactions mediated by immunoglobulin E (IgE), after allergen exposure. Probiotics is considered has strong influence on the regulation of primary immunophysiology in intestinal mucosal barrier and might be useful to prevent allergy attacks.Purpose: To study the benefits of Lactobacillus casei Shirota strain L in preventing allergy attacks through the mechanism  of immunomodulatory systems that inhibit the production of IgE. Methods:The study was quasi-experimental  with pretest-posttest design. The subjects were 45 students with history of allergic rhinitis. Serum IgE levels were measured before and after given milk containing probiotics for one month. Results: With a paired t test, there was significant difference of the average IgE levels between before (291.88 IU/L) and after one month. Probiotic supplementation (141.43 IU/L),p<0.05. Conclusion: Supplementation of probiotic Lactobacillus casei Shirota strain L is useful in preventing allergy attacks.  Keywords: allergic rhinitis, probiotics, immunoglobulin E (IgE) Abstrak :  Latar belakang: Rinitis alergi adalah reaksi peradangan mukosa hidung yang diperantarai oleh imunoglobulin E (IgE) setelah terjadi pajanan alergen. Pemberian probiotik dianggap mempunyai pengaruh yang kuat terhadap regulasi imunofisiologi primer dalam barier mukosa usus. Tujuan:Mengkaji manfaat suplemen probiotik Lactobacillus casei L shirota strain dalam mencegah serangan alergi melalui mekanisme sistem imunomodulator yang menghambat produksi IgE. Metode: Desain penelitian adalah eksperimental kuasi case control dengan rancangan pretest-postest design. Subjek penelitian adalah 45 orang yang mempunyai riwayat rinitis alergi, diambil darah sampel untuk diperiksa kadar IgE sebelum dan setelah diberi susu yang mengandung probiotik selama satu bulan. Hasil: Dengan paired t test, terdapat perbedaan bermakna antara rata-rata kadar IgE sebelum suplementasi (291,88 IU/L) dan setelah diberi suplementasi probiotik Lactobacillus casei Lshirota strain selama satu bulan (141,43 IU/L), p<0,05. Kesimpulan: Suplementasi probiotikLactobacillus casei L shirota strain bermanfaat dalam mencegah serangan alergi melalui mekanisme imunomodulator yang menghambat produksi IgE. Kata kunci: rinitis alergi, probiotik, imunogobulin E (IgE)
Validity and Reliability of Knowledge, Attitude and Practice Questionnaire of Ear Care among Medical Workers Arsyada Hakama Syakuro; Deoni Daniswara; Adnan Abdullah; Rizka Fakhriani; Asti Widuri
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

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Abstract

The auditory system is a vital and prominent component of human. It is imperative for individuals to prioritize the maintenance of this organ throughout their lives. These methods encompass the maintenance of ear cleanliness, safeguarding against excessive noise exposure, preventing accidents, and warding off ear infections and disorders. The aim of this study was to determine the validity and reliability of knowledge, attitude, and practice about ear care among medical workers. This study uses a descriptive-analytic method with a cross-sectional design. The ear care questionnaire comprising of knowledge, attitude and practice translated and applicated for 45 participants, the validity test using Pearson’s correlation and reliability test evaluation determined by Cronbach’ s alpha. The ear care questionnaire Indonesian version found Pearson’s correlation of all items r above 0.35 or strongly valid, and the Cronbach’s alpha coefficient was 0.749 (adequate). Indonesian version of knowledge, attitude, and practice about ear care is valid and reliable, the result of assessment can indicate the needed of public awareness through education and health promotion.
Effect of Educational Videos on Knowledge, Attitudes, and Practices of Ear Health: A Quasi-Experimental Study among Medical Students in Yogyakarta, Indonesia Arsyada Hakama Syakuro; Asti Widuri; Rizka Fakhriani
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 8 No. 11: NOVEMBER 2025 - Media Publikasi Promosi Kesehatan Indonesia (MPPKI)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v8i11.8497

Abstract

Introduction: Many hearing problems arise from a lack of understanding about ear health and proper care. Lack of public awareness of how to maintain ear health, coupled with improper ear cleaning techniques such as using cotton swabs or other instruments, can lead to earwax blockages or infections in the outer ear. Some ear infections can be prevented by public health promotion activities, including videos. This study aims to examine the effect of ear health education videos on knowledge, attitudes, and ear cleaning practices. Methods: This study used a quasi-experimental pre-test and post-test design. Sixty-three medical students were recruited using consecutive sampling. After obtaining informed consent, they were asked to complete a valid and reliable Indonesian version questionnaire on knowledge, attitudes, and practices (KAP) of ear health, watch an educational video about anatomy, physiology, and ear health safety care, and then complete the same questionnaire again. Results: The research respondents were 38 (60.3%) female students and 25 (39.7%) male students. Overall KAP scores improved significantly after video intervention (Z = -3.92, p < 0.001, r = 0.49, 95% CI = [0.28-0.66]). Stratified analysis of each domain revealed heterogeneous outcomes. Knowledge and attitude scores showed a non-significant increase, but practices improved significantly with a small to moderate effect (Z = -2.03, p = 0.042, r = 0.26, 95% CI = [0.40-3.00]), particularly regarding avoidance of unsafe ear cleaning tools and noise exposure. Conclusion:Ear health video education did not substantially alter knowledge and attitude, but it produced significant behavioral shifts in self-reported ear-care practices. The absence of substantial change in knowledge and attitude ratings may be due to a high baseline level in this cohort, indicating a possible ceiling effect. This behavioral shift aligns with theories suggesting that multimedia interventions effectively improve procedural skills and self-efficacy, aiding the application of existing knowledge into positive action rather than promoting deeper conceptual change.
Co-Authors Adnan Abdullah Arsyada Hakama Syakuro Deoni Daniswara Lilis Suryani Rizka Fakhriani