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All Journal Jurnal Ilmu Kefarmasian Indonesia Asian Journal of Social and Humanities
HARMIDA HARMIDA
UNIVERSITAS SRIWIJAYA
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Earth & Planetary Sciences Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health

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Activity Tests of Bioactive Material of Salung Leaf (Psychotria viridiflora Reinw. Ex. Blume) against Salmonella thypi Bacteria In Vitro And In Vivo SALNI SALNI; HANIFA MARISA; HARMIDA HARMIDA
JURNAL ILMU KEFARMASIAN INDONESIA Vol 14 No 1 (2016): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (417.075 KB)

Abstract

Activity test of bioactive material of Salung leaf (Psychotria viridiflora Reinw. ex. Blume) against Salmonella thypi in vitro and in vivo has been carried out. Bioactive material was obtained from the maceration and followed by fractionation of liquid-liquid fractionation. Antibacterial activity test performed in vitro to determine the value of the minimum inhibitory concentration (MIC) and in vivo to determine the ability of bioactive cure diarrhea in in rats (Rattus norvegicus) infected by Salmonella typhi. Treatment of bioactive material given is 0, 10, 50 and 100 mg kg-1 of weight. The results showed that the MIC of salung leaf’s bioactive material to Salmonella typhi was 250 μg mL-1. Bioactive ingredient at dose of 10 and 50 mg kg-1 were able to decrease the number of bacterial colonies to 4.14x106 cfu g-1 and 5.4x105 cfu g-1, less than 5.04x106 cfu g-1 as control. Bioactive material in weight of 100 mg kg-1 of weight could reduce the population of Salmonella typhi to zero after 12 days of treatment. The ability to reduce the amount of bacterial colonies of the bioactive material 100 mg kg-1 of weight is equal to the ability of positive control chloramphenicol 10 mg kg-1 of weight.
Ethnobotany of Medicinal Plants for Infectious Diseases in the Besemah Tribe, Lahat Regency, South Sumatra Province, Indonesia Nina Tanzerina; Desti Safitri; Harmida Harmida; Nita Aminasih; Juswardi Juswardi
Asian Journal of Social and Humanities Vol. 2 No. 1 (2023): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v2i1.163

Abstract

Knowledge about medicinal plants in the Besemah tribe community in Jarai District and Sukamerindu District, Lahat Regency, South Sumatra Province, has long been known and used for generations and stored as local wisdom of the community. The use of medicinal plants as one of the community's solutions to cure infectious diseases, with natural medicinal materials the side effects caused are relatively less. This study aims to inventory and identify the types of medicinal plants and types of medicinal plants typical of the Besemah tribe, how to process, how to use, and how to use specifically to treat infectious diseases in the Besemah tribe in Jarai District and Sukamerindu District, Lahat Regency, South Sumatra Province. This research will be conducted from January to March 2023. The study was conducted using quantitative descriptive methods by conducting interviews with 9 traditional medicine (battra) as sources of information. The results showed that plants used as medicine by the Besemah tribe community as many as 94 species of plants from 47 families to treat 29 infectious diseases. There are seven species of typical plants of the Besemah tribe, namely Tetap kadam (Hadgsonia macrocarpa (Blume) Cogn.), Tetungau (Debregeasia longifolia (Burm.f) Wedd), Memban burung (Donax canniformis (G.Forst) K.Schum), Temperingat (Rubus moluccanus L.), Tapal selembar (Monophyllaea horsfieldii R.Brown), Sedingin hutan (Fissistigma fulgens (Hook.f & Thomson) Merr.), Memaye (Leea indica (Burm.f.) Merr), and the typical way of processing is that the stem is cut, the water is collected and drunk directly. The most widely used plant part is the 38% leaf part. The most processing method is used by boiling 46% and the most use method by drinking 53%.
Co-Authors Desti Safitri HANIFA MARISA Juswardi Juswardi Nina Tanzerina Nita Aminasih Salni Salni