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All Journal Jurnal Ilmu Kefarmasian Indonesia
Sri Sumarni
Poltekkes of Health Ministry Semarang
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Pemanfaatan Ekstrak Kelopak Bunga Rosella (Hibiscus Sabdariffa Linn.) untuk Meningkatkan Kadar Hemoglobin dan Hematokrit Remaja Putri Penderita Anemia Luluk Handayani; Sri Sumarni; Donny Kristanto Mulyantoro
JURNAL ILMU KEFARMASIAN INDONESIA Vol 20 No 1 (2022): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v20i1.1213

Abstract

This research aims to prove the provision benefits of Rosella (Hibiscus sabdariffa Linn.) calyx extract to increase hemoglobin and hematocrit levels in female adolescents anemia. This research is a true experiment with a randomized pre-test and post-test control group design. Totals of samples were 40 female adolescents with anemia according to the inclusion and exclusion criteria divided by randomization sampling technique, consisting of two groups intervention groups and control groups. Data analysis used paired t-test statistical test to determine the difference between pretest and post-test each group and an independent t-test to determine the difference between the different groups. The average difference in hemoglobin and hematocrit levels in the intervention group was higher than in the control group. The average difference in hemoglobin levels in the intervention group was 1.8 g/dL in and the control group was 0.9 g/dL, (p < 0.05), The difference in the average hematocrit level in the intervention group was 5.6% and the control group was 2.7% (p < 0.05). The researchers also found significant statistics differences between hemoglobin and hematocrit levels of female adolescents from intervention and control groups s with a p-value < 0.05. The combination of Rosella (Hibiscus sabdariffa Linn.) calyx extract and Fe2+ tablet was effective to increasing hemoglobin and hematocrit levels in female adolescents with anemia.
Co-Authors Donny Kristanto Mulyantoro Handayani, Luluk