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All Journal Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Journal Pharmasci (Journal of Pharmacy and Science) Jurnal Abdi Masyarakat Kita Jurnal Farmasi Sains dan Praktis Borneo Journal of Pharmacy
Fitria Dewi Yunitasari
Akademi Farmasi Surabaya
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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HUBUNGAN TINGKAT PENDIDIKAN DAN PENGETAHUAN PETUGAS APOTEK TERHADAP PELAYANAN ANTIBIOTIK ORAL DI KABUPATEN SIDOARJO, INDONESIA Ilil Maidatuz Zulfa; Fitria Dewi Yunitasari
Majalah Farmasi dan Farmakologi Vol. 25 No. 2 (2021): MFF
Publisher : Faculty of Pharmacy, Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/mff.v25i2.13151

Abstract

Salah satu faktor yang berkontribusi pada resistensi bakteri adalah penggunaan antibiotik yang tidak rasional seperti pada fenomena penggunaan antibiotik tanpa resep. Fenomena penggunaan antibiotik tanpa resep yang terjadi tidak lepas dari pola pikir masyarakat maupun petugas apotek. Kurangnya pengetahuan petugas apotek tentang antibiotik, resistensi bakteri, dan aspek legal dari dispensing antibiotik berkontribusi pada pemberian layanan antibiotik di komunitas di beberapa negara dengan pendapatan rendah. Penelitian ini bertujuan untuk menganalisis hubungan tingkat pendidikan dan pengetahuan petugas apotek tentang antibiotik terhadap pelayanan antibiotik oral yang mereka berikan di Kabupaten Sidoarjo. Studi observasional dengan pendekatan secara cross sectional dilakukan kepada petugas apotek dengan membagikan kuisioner secara daring. Sebanyak 233 petugas apotek dari 56 apotek di Kabupaten Sidoarjo telah dilibatkan dalam penelitian. Sebagian besar dari responden memiliki pengetahuan baik tentang antibiotik (48,93%) serta hanya melayani antibiotik oral hanya berdasarkan atas resep (68,00%) walaupun masih sekitar 30,00% yang melayani berdasar resep dan non resep. Terdapat hubungan yang signifikan antara tingkat pengetahuan petugas apotek tentang antibiotik terhadap bentuk pelayanan antibiotik oral yang diberikan (p-value 0,001). Peningkatan pengetahuan petugas apotek tentang antibiotik akan berkontribusi pada bagaimana mereka melayani anitibiotik berdasarkan aturan yang berlaku sehingga peningkatan pengetahuan tentang antibiotik ditengah petugas apotek yang bertugas di layanan sangat penting untuk dilakukan.
EDUKASI GENERASI MUDA SIAP VAKSINASI COVID-19 Ilil Maidatuz Zulfa; Fitria Dewi Yunitasari
Jurnal Abdi Masyarakat Kita Vol 1 No 2 (2021): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1310.259 KB) | DOI: 10.33759/asta.v1i2.149

Abstract

Vaccination program for Covid-19 in Indonesia has been conducted since 13th of January 2021. However, the vaccination process has been accompanied by an increase false information that can lead to the decrease of public acceptance. Therefore, public education strengthening is a key concerns to succed the vaccination program. This was a report of public education strengthening activity conducted in April 2021 aimed to increase public awareness about Covid-19 vaccination program. There were 34 highschool students joined in the event. The result showed after joining the events 14,7% of students who refuse to support vaccinated program claim thet they are ready for vaccination. In conclusion, continuity in public education strengthening is essential to increase public acceptance about Covid-19 vaccination.
Edukasi Masyarakat Mengenai Suplemen dan Vitamin untuk Tumbuh Kembang Remaja dan Covid-19 Ilil Maidatuz Zulfa; Fitria Dewi Yunitasari
Jurnal Abdi Masyarakat Kita Vol 2 No 2 (2022): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/asta.v2i2.284

Abstract

Covid-19 pandemic has hit worldwide for three years. During the pandemic, a proper diet and optimum consumption of vitamins and suplements will help to maintain the immune system. However, there is still lack of public awareness in fulfillness the nutrition need during pandemic. Hence, it is essentials to increase public knowledge and awareness through the through the provision of information in order to make people easier in choosing the best diet, vitamins and suplement to combat the pandemic.
A SURVEY OF PHARMACY STAFF KNOWLEDGE RELATED TO ANTIBIOTICS IN SIDOARJO, INDONESIA Ilil Maidatuz Zulfa; Fitria Dewi Yunitasari
Jurnal Farmasi Sains dan Praktis Vol 6 No 2 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i2.3795

Abstract

Antibiotics resistance still remains the problem in treating infection disease both in developing and developed country. One of the factor contribute to the increase of antibiotics resistance is irrational antibiotics use without prescriptions. There is still lack of information about factors related to the antibiotics dispense by pharmacy staff. This study was aimed to observe pharmacy staff knowledge about the pharmacology and the regulation of antibiotics. A cross sectional online survey using questionnaire was conducted to pharmacy staff who work for service in Sidoarjo from February to April 2020. The knowledge of antibiotics was classified into lack, enough, and good knowledge. A total of 233 respondents from 56 pharmacy recruited in this study. Of them, 17,17% were pharmacist; 10,73% were pharmacy technician; 52,36% were pharmacy assistant and 19,74% non pharmacy worker. Overall the majority of respondents had a good knowledge about antibiotics (48,93%). However, most of them did not know that only pharmacist who had responsible to dispense antibiotics based on prescriptions (58,37%), fail to describe antibiotics indications (46,35%) and had poor knowledge about the minimum length of antibiotics course (58,37%). Educating and upskilling pharmacy personel about antibiotics will minimize the irrational use of antibiotics which lead to the increase of antibiotics resistance caused by the lack information received by patients.
Potential Drug-drug Interactions Analysis in Children Out-patients with Bronchopneumonia Medication Prescriptions Ilil Maidatuz Zulfa; Fitria Dewi Yunitasari; Susanty Kartika Dewi
Borneo Journal of Pharmacy Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i2.1316

Abstract

Drug-drug interactions (DDIs) is defined as the alteration of efficacy and toxicity of some drugs in the presence of other drugs. In the treatments of bronchopneumonia in outpatient settings, there is a lack of documentation of DDIs. This study was aimed to observe the potential DDIs on the prescriptions of children with bronchopneumonia. An observational and cross-sectional study was conducted on outpatient children with bronchopneumonia prescriptions during 2017. Potential for DDI was identified by online drug interaction checkers. The potential DDI then classified based on its severity (minor, moderate, and major) and mechanism (pharmacokinetic and pharmacodynamic). Among 86 prescriptions analyzed, potential DDIs observed at 48.84% of it. Of that, there were 67 potential DDIs where 72.34% of it were categorized as moderate. The majority of potential DDIs was pharmacodynamic interaction (76.12%) with the most frequently involved drug pair was Ephedrine-Salbutamol (29.85%). Children outpatients with bronchopneumonia are at risk of potential DDIs, especially to minor and moderate potential DDIs. Prescriptions screening for potential DDIs followed by monitoring of therapeutical effects and associated adverse drug events will optimize patient safety.
Prescribed Daily Dose (PDD) Antibiotik Untuk Penyakit Gigi di Salah Satu Apotek di Surabaya Ilil Maidatuz Zulfa; Fitria Dewi Yunitasari
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 2 No. 2 (2017): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v2i2.77

Abstract

ABSTRAKAntibiotik sistemik banyak diresepkan oleh dokter gigi baik sebagai profilaksis maupun penanganan infeksi. Tingginya peresepan antibiotik pada infeksi gigi dan periodontal akan berpotensi pada peningkatan resistensi bakteri karena penggunaan yang berlebihan. Tujuan dari penelitian ini adalah untuk menginvestigasi pola peresepan, Prescribed Daily Dose (PDD) dan rasio PDD/DDD yang ditetapkan WHO setiap antibiotik yang diresepkan untuk penyakit gigi. Studi cross-sectional retrospektif dilakukan pada rekam resep tahun 2016 di salah satu Apotek di Surabaya. Sebanyak 136 resep untuk penyakit gigi telah dianalisis dalam penelitian ini. Rata-rata usia pasien adalah 38,92+12,96 tahun. Antibiotik yang paling banyak diresepkan adalah Golongan –Laktam yaitu Amoksisilin (50,72%) dan Amoksisilin+Asam Klavulanat (3,62%) diikuti oleh golongan Linkosamid yaitu Klindamisin (28,99%) dan Linkomisin (5,80%), serta golongan Nitroimidazol yaituMetronidazol (5,07%). PDD Antibiotik yang diresepkan lebih rendah dibanding DDD yang ditetapkan WHO kecuali Amoksisilin (1509,2 mg/pasien/hari; rasio PDD/DDD 1,59), Amoksisilin+Asam Klavulanat (1368,42 mg/pasien/hari; rasio PDD/DDD 1,37), Eritromisin (1500,00 mg/pasien/hari; rasio PDD/DDD 1,50), dan Levofloksasin (500,00 mg/pasien/hari; rasio PDD/DDD 1,00). Terdapat perbedaan antara nilai PDD beberapa antibiotik dengan nilai DDD yang ditetapkan WHO dimana dalam penelitian ini nilai PDD lebih merefleksikan densitas penggunaan antibiotik.Kata kunci: Prescribed Daily Dose (PDD), Antibiotik, Infeksi gigi.ABSTRACTSistemic Antibiotics are prescribed by dentists not only for treatment of infection but also for profilactics. Most of dental and periodontal diseases are best treated by operative intervention and oral hygiene measures, so that the use of sistemic antibiotics are very limited. High rates of sistemic antibiotics prescribing in densitry can lead to bacterial resistance due to overuse of antibiotics. The aim of the study was to investigate the antibiotics prescribing patterns in densitry, Prescribed Daily Dose (PDD), and PDD/WHO’s Defined Daily Dose (DDD) ratio. A retrospective cross-sectional study was conducted on 2016 prescription records at a private pharmacy in Surabaya, East Java, Indonesia. A total 136 prescription records were analyzed. The average age of patients was 38,92+12,96 years old. The most common antibiotics prescribed in densitry was –Lactam group which were Amoxycillin (50,72%) and Amoxycillin+Clavulanic Acid (3,62%) followed by Linkosamide group w Clindamycin (28,99%) and Lincomycin (5,80%), and Nitroimidazol group which was Metronidazole (5,07%). The PDD of Antibiotics prescribed was lower than each WHO’s DDD except Amoxycillin (1509,2mg/patient/day; PDD/DDD ratio 1,59), Amoxycillin+Clavulanic Acid (1368,42 mg/patient/day; PDD/DDD ratio 1,37), Eritromisin (1500,00 mg/patient/day; PDD/DDD ratio 1,50), dan Levofloksasin (500,00 mg/patient/day; PDD/DDD ratio 1,00). There was a difference between PDD and WHO’s DDD. PDD was more likely reflect the density of antibiotic usage. Key Words: Prescribed Daily Dose (PDD), Antibiotics, Dental Infections
Hospitalisasi Pasien Skizofrenia di Rumah Sakit Jiwa Menur Surabaya Fitria Dewi Yunitasari; Ilil Maidatuz Zulfa
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 3 No. 2 (2018): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v3i2.118

Abstract

ABSTRAKSkizofrenia merupakan gangguan atau kumpulan gangguan mental yang mempengaruhi pemikiran, persepsi, dan perilaku sosial dan penyebabnya sebagian besar masih belum diketahui. Pengobatan farmakologis skizofrenia menggunakan obat-obat golongan antipsikotik terutama dalam jangka waktu lima tahun setelah episode akut pertama muncul. Penggunaan antipsikotik berpotensi menimbulkan kejadian hospitalisasi yang dapat menurunkan kualitas hidup pasien terkait penurunan fungsi sosial pasien skizofrenia. Penelitian ini bertujuan menganalisis potensi jenis kelamin dan jenis pengobatan antipsikotik sebagai faktor prediktor hospitalisasi pasien skizofrenia. Analisis cross sectional jenis kelamin dan penggunaan antipsikotik dilakukan pada rekam medis pasien rawat inap di Rumah Sakit Jiwa Menur Surabaya Bulan Oktober 2017 yang didiagnosis skizofrenia (ICD-10 F20). Faktor prediktor hospitalisasi pasien  dianalisis menggunakan uji Chi-square for goodness of fit yang membandingkan perbedaan jumlah frekuensi antar kategori pada masing-masing faktor prediktor. Faktor jenis terapi antipsikotik digolongkan menjadi tipikal, atipikal, dan kombinasi. Hasil menunjukan terdapat perbedaan jumlah pasien pada tiga jenis terapi yang berbeda (p-value 0,000) dimana sebagian besar pasien yang dirawat dirumah sakit menerima antipsikotik tipikal (47,41%). Perbandingan jenis kelamin tidak menunjukkan perbedaan yang signifikan pada pasien yang dirawat. Dapat disimpulkan jenis antipsikotik tipikal kemungkinan dapat mempengaruhi kejadian hospitalisasi pada pasien skizofrenia. Kata kunci: Skizofrenia, antipsikotik tipikal, antipsikotik atipikal, hospitalisasi.ABSTRACTSchizophrenia is a mental disorder that affect thought, perception, and social behaviours. Most of causes of schizophrenia are unknown. Pharmacological treatments of schizophrenia use antipsychotics especially during  five years after first acute episode observed. The use of antipsychotics potentially lead to hospitalization that can affect to patients’ quality of life. This study was aimed to analyze the potential of gender and types of antipsychotic treatments as predictor factors in hospitalization of schizophrenia patients. Cross sectional analysis in gender and types of antipsycotics was conducted to medical records of inpatients at Rumah Sakit Jiwa Menur Surabaya diagnozed with Schizophrenia (ICD-10 Code F20) in October 2017. Chi-square for goodness of fit test was used to determine the difference amount of patients among different gender and different types of antipsychotics used as predictor factors. Types of antipsychotics used was classified into three categories which were patients who received typical antipsychotic, atypical antipsycotic and combination. The results showed that there was a significant difference in amount of hospitalized patients who received typical antipsychotic, atypical antipsycotic and combination (p-value 0,000) which most of hospitalized patients received atypical antipsychotics (47,41%).On the other hand, the proportion of gender among hospitalized patients was found have no significant difference. In conclusion, types of antipsychotics used might related to the hospitalization of schizophrenia patients.Keywords: Schizophrenia, Typical antipsychotic, Atypical antipsychotic, Hospitalization.
Evaluasi Peresepan Terapi Bronkopneumonia Anak di Unit Rawat Jalan Rumah Sakit Umum Daerah Bangkalan, Indonesia Ilil Maidatuz Zulfa; Fitria Dewi Yunitasari; Nisa Dwi Ratnadi
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 4 No. 2 (2019): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v4i2.138

Abstract

ABSTRAKBronkopneumonia adalah salah satu manifestasi klinik dari pneumonia yang paling sering muncul pada anak. Obat yang diresepkan seringkali mengkombinasikan antibiotik dengan obat-obat simtomatis dan tidak sedikit yang berupa polifarmasi. Peresepan polifarmasi berpotensi pada kurang efisiennya pengobatan. Peresepan yang kurang efisien akan berakibat pada efektivitas dan keamanan terapi, eksaserbasi atau perpanjangan gejala dan penyakit, serta tingkat keamanan pada pasien, serta peningkatan biaya terapi. Tujuan dari penelitian ini adalah untuk mengevaluasi peresepan terapi bronkopneumonia pada anak. Studi observasional secara retrospektif dilakukan pada peresepan bronkopneumonia anak usia 0-14 tahun di Unit Rawat Jalan Rumah Sakit Umum Daerah Syarifah Ambami Rato Ebu Bangkalan, Indonesia selama tahun 2016. Evaluasi peresepan mengacu pada WHO prescribing indicator yang terdiri dari 5 poin. Hasil evaluasi pada penelitian ini menunjukkan bahwa rata-rata jumlah obat yang diresepkan adalah 4,60 item per kunjungan, obat generik diresepkan sebanyak 53,88%, antibiotik sebesar 69,31%, obat injeksi sebesar 0,99%, dan obat dalam Formularium Nasional tahun 2017 sebesar 48,28% dalam satu tahun periode peresepan. Sehingga, terdapat empat indikator yang belum sesuai dengan yang ditentukan WHO. Walaupun pemberian antibiotik sangat disarankan pada terapi bronkopneumonia, peresepan antibiotik masih memerlukan evaluasi lebih lanjut terkait rasionalitasnya. Selain itu, rendahnya peresepan berdasarkan Formularium Nasional tahun 2017 menunjukkan masih relatif rendahnya optimasi penggunaan obat yang cost-effective menurut kebijakan nasional.Kata kunci: Bronkopneumonia, Peresepan, Rawat Jalan.ABSTRACTBronchopneumonia is one of pneumonia manifestations commonly occur in children.The treatments usually combine antibiotics and symptomatic drugs in the form of polypharmacy.Polypharmacy can leads to inefficient treatmentsthat can cause ineffective and unsafe treatment, exacerbation or prolongation of illness, distress, harm to the patient and increasing the cost therapy.The aim of the study was to evaluate the prescribing for bronchopneumonia treatment in children. A retrospective observational study was conducted on prescriptions written for children with bronchopneumonia age 0-14 y.o in outpatient departement of Rumah Sakit Umum Daerah Syarifah Ambami Rato Ebu Bangkalan, Indonesia during 2016.WHO prescribing indicators was used to evaluate the prescribing. The result showed that the average number of medicine per encounter was 4.60 items, including medicine prescribed by generic name was 53.88%, antibiotics prescribed was 69.31%, injection prescribed was 0.99%, and medicines prescribed from National Formulary 2017 was 48.28%. Hence, there were four indicators found to be innapproppriate to WHO recomendation. Although antibiotics are highly recommended in bronchopneumonia, the usage of antibiotics still need an assessment related to its rationality. In addition, low percentage of medicines National Formulary showed low usage of cost-effective drugs based on the goverments policy.Keywords: Bronchopneumonia, Prescribing, Outpatients.
Co-Authors Nisa Dwi Ratnadi Susanty Kartika Dewi Zulfa, Ilil Maidatuz