Article Per Year (5 Year)
p-Index From 2020 - 2025
0.751
P-Index
This Author published in this journals
All Journal Budapest International Research in Exact Sciences (BirEx Journal)
Florenly Florenly
Departement of Medicine, Faculty of Medicine, Universitas Prima Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Physics Transportation

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Effectiveness of Ethanol Extract Mangosteen Peel (Garcinia Mangostana L.) in Accelerating Post-Tooth Extraction Healing in Wistar Rats Dong Qian; Florenly Florenly; Liena Liena; Dewi Riastawaty Purba
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3473

Abstract

Tooth extraction will cause a wound in the form of alveolar bone that opens in the oral cavity. Mangosteen peel has various pharmacological effects such as anti-inflammatory, antioxidant, antidiabetic, and antibacterial. The goal of this study was to find out the effectiveness of Mangosteen Peel Ethanol Extract (Garcinia mangostana L.) 45% with 90% in speeding up the healing time of post-tooth extraction wounds in Wistar rats. This type of research is an experimental laboratory with a post-test pattern only control group design. Conducted at the Laboratory of Pharmacology & Laboratory of Traditional Medicine Faculty of Pharmacy, University of North Sumatra January-March 2021. The animal is a male Wistar rat of 32 who is physically healthy. The size of the sample is determined by Federer's formula, the minimum sample size for each treatment is 16 rats. The results of the study that there is a significant relationship between the amount of fibroblast tissue per field of view in Wistar Rats after tooth extraction with the administration of mangosteen peel (Garcinia mangostana L.) with a concentration of 45% and mangosteen peel (Garcinia mangostana L.) concentration 90%, p = 0.036 (p<0.05). Mangosteen skin extract (Garcinia mangostana L.) is 45% and 90% effective in speeding up wound healing time after extraction of rat teeth Wistar. Mangosteen skin extract (Garcinia mangostana L.) is 90% more effective than turmeric extract (Curcuma longa) 45% in speeding up wound healing time post-extraction of rat teeth Wistar due to the flavonoid content in mangosteen skin extract (Garcinia mangostana L.) 90% which helps accelerate wound healing higher than skin extract Mangosteen (Garcinia mangostana L.) 45%. 
The Healing Analysis of II Degree Burn from Surgery Essential Oil Ointment (Curcuma Longa) in Wistar Rats (Rattus Norvegicus) Chen Wei; Florenly Florenly; Dewi Riastawaty Purba; Fioni Fioni
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3474

Abstract

Data in Indonesia the death rate from burns is still high at around 40%, mainly caused by severe burns. The most potential medicinal turmeric plant is its rhizome, which contains the phenolic compound curcumin and essential oils. Some of the benefits of turmeric antioxidants, anti-inflammatory, anti-cancer, acetylcholinesterase activity inhibitors, anti-fungal, and anti-bacterial. This study aims to find out the phytochemical content and effects of Turmeric Essential Oil Ointment (Curcuma longa Linn) in curing grade II burns in Wistar rats (Rattus norvegicus). This type of research is experimental with a pre-post approach and post-test control group design. The study was conducted at Riwandi Pet Shop and Animal House March-May 2021. The research sample is turmeric (Curcuma longa) obtained from a traditional market in the city of Medan and identified in herbarium Medanese (MEDA), Laboratoirum Taxonomy of Plants, Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), University of North Sumatra, Medan. The test animal is a Wistar strain rat with as many as 20 tails divided into 4 treatment groups, so each group consists of 5 rats. The results of the study contained significant differences in the epithelial period of the standard group, 10% turmeric ointment and 15% against the control group. However, in the turmeric ointment group and the standard group, there was no difference in epithelialization periods. This is evident from the value P < 0.05 (Value P = 0.029). The healing effects of burns possessed by Turmeric ointment are both 10% and 15% and nebacetin ointment as standard shows significant differences. Where the wound contraction rate of turmeric ointment is 15% better than nebacetin ointment as standard. But in both turmeric ointments, both 10% and 15% and nebacetin ointment as standard did not show significant differences in the parameters of the epithelial period.
Effects of Turmeric Ethanol Extract on Pancreatic Amylase Enzyme in Doxorubicin-Induced Wistar Mice Wen Shiqi; Florenly Florenly; Johannes Bastira; Fioni Fioni
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.3559

Abstract

Type II diabetes mellitus indicates the presence of chronic hyperglycemia and results from progressive failure of pancreatic β cells in which the amount of insulin is insufficient to meet metabolic demands and is characterized by peripheral insulin resistance and impaired insulin secretion. Turmeric (Curcuma longa Linn) has been widely researched and used for antioxidants, antivirals, anti-inflammatories, as well as its potential as a functional food for pancreatic-related diseases. The study's goal was to test the effectiveness of turmeric ethanol extract against pancreatic amylase enzymes in doxorubicin-induced Wistar mice (lowered fasting KGD, 2 hoursPP, HbA1C, in doxorubicin-induced male mice). This type of research is an experimental study, in early March 2021, conducted at the Laboratory of Pharmaceutical Pharmacology of the University of North Sumatra. The animals used in the study were male rats weighing 150–200g. The results in the treatment group iii treatment group (ethanol extract Curcuma longa 600g) had blood sugar levels of 74.2014 ± 3.78 mg/ml had a neggant difference (P<0.05) with the negative control group and did not have a significant difference (P>0.05) with the positive control group. Ethanol extract Curcuma longa doses of 200 mg/kg bb, 400 mg/kg bb, and 600 mg/kg bb had significantly different blood glucose levels decreased activity (P<0.05) with negative control groups given only CMC-Na and doxorubicin. Curcuma longa extract doses of 200 mg/kg bb, 400 mg/kg bb, and 600 mg/kg bb had significantly different hbA1c reduction activity (P<0.05) with negative control groups given only CMC-Na and doxorubicin. Advice, for researchers, can further do antidiabetic testing by looking at insulin expression after doxorubicin-induced and tested measurement of antioxidant levels such as GSH and Catalase.
Effect of Respiratory Relaxation Techniques on Pain Adaptation in Maternity Mothers at RSU Royal Prima in 2020 Wang Chunxiang; Florenly Florenly; Liena Liena; Dewi Riastawaty Purba
Budapest International Research in Exact Sciences (BirEx) Journal Vol 4, No 1 (2022): Budapest International Research in Exact Sciences, January
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v4i1.3476

Abstract

Every year an estimated 529,000 women die as a result of complications arising from pregnancy and childbirth. Labor pain is a physiological condition, an unpleasant feeling that occurs during labor. Nonpharmacological pain management can increase satisfaction during labor because the patient can control his feelings and strength, one of which is the texture of respiratory relaxation. The purpose of this study was to find out the effect of respiratory relaxation techniques on pain adaptation in maternity mothers. This type of research is descriptively correlational, using the One Group Pretest-Postest approach. Location in RSU Royal Prima Jalan Ayahanda Number 68A, Sei Putih Tengah, Medan Petisah, North Sumatra, september - November 2020. The population of 43 people, determining the number of samples with the formula slovin, so that the sample was obtained as many as 30 people. The data analysis used is a normality test using the Shapiro Wilk test, because the number of samples is <50. Bivariate analysis of the data is distributed normally using an at-dependent test (paired t-test), while if the data is not distributed normally using the Wilcoxon Signed Rank Test, with a meaningful limit of <0.05. The results of the study score change in the level of pain Wilcoxon test results at the time of the pre-test test the result of a mean value of 3,466, at the time of the post-test test the mean value of 3,166. So the result of the value Z = -2,714 then p-value as much as 0.007<0.05 so that it is concluded ho rejected and Ha received, which means there is an effect of giving respiratory relaxation techniques to changes in pain in maternity mothers when-I at RSU Royal Prima in 2020.
Co-Authors Chen Wei Dewi Riastawaty Dong Qian Fioni, Fioni Johannes Bastira Ginting Liena Liena Wang Chunxiang Wen Shiqi