Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Jurnal Farmasi Higea
Riri Hariyani
Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang
Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Profil Disolusi Parasetamol Mukoadhesif Menggunakan Kombinasi Polimer Natrium Karboksimetilselulosa dan Gom Arab Auzal Halim; Riri Hariyani; Maria Dona Octavia
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (776.626 KB) | DOI: 10.52689/higea.v2i1.27

Abstract

Dissolution profiles of  4 formulas of paracetamol  mucoadeshif  formulas has been done. The test done by using pH 5,8 phosphate buffer as dissolution medium with rowing method, as stated in the Indonesian Pharmacopoeia IV edition. Paracetamol concentrations were measured by UV spectrophotometer at 243 nm. The average dissolution from each formula at 60 minutes are 10.1641%, 15.015%, 11.0631% and 11.8493% respectively. Adhesion test of some mucoadhesive granule adhesion test formulated by using Na-CMC single polymer and a combination of Na-CMC and gum arabic done bioadhesif in vitro assay using rabbit intestinal tissue. The result showed that the combination of Na-CMC polymer and gum Arabic can be used as a polymer bioadhesif because it shows results that meet the requirements of the test bioadhesif.
Co-Authors Auzal Halim Maria Dona Octavia