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All Journal Jurnal Kedokteran Brawijaya Jurnal (FORSINTA) Informatika, Sistem Informasi dan Kehutanan
Dessy Setiawati
Program Studi Magister Ilmu Biomedik, Fakultas Kedokteran Universitas Brawijaya
Agriculture, Biological Sciences & Forestry Computer Science & IT Medicine & Pharmacology

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Peningkatan Jumlah Apoptosis Airway Smooth MuscleBerhubungan dengan Peningkatan + Jumlah Sel T CD8 pada Model Mencit Asma Setiawati, Dessy; Kusuma, HMS Chandra; Kusworini, Kusworini
Jurnal Kedokteran Brawijaya Vol 25, No 3 (2009)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (767.727 KB) | DOI: 10.21776/ub.jkb.2009.025.03.4

Abstract

Airway  remodeling  is  an  important  thing  in  asthma.The  increase  of  airway  smooth  muscle  mass  is  a prominent  feature  of  asthmatic  airway  remodeling.  The importance  role  of  airway  smooth  muscle cell  (ASM) + apoptosis in airway remodeling is unknown.T cell also had important role in asthma, whereas CD4 T cell +role  in  airway  remodeling  has  already  known,  but  how  CD8   T cell  role  in  airway  remodeling  is  still  unclear.  A randomized  control  group experimental study  used Balb/c mice, that  categorized into  2 groups: asthma and control.  Asthma group was sensitized by ovalbumin intraperitoneally  in  day 0 and 14, followed  by inhalation +every  2-3  days  for  6  weeks.  In  week  8,  all  of  mice  were  terminated.   The  expression  of  CD8   T  cell  lymphocyte was  examined  through  immunohistochemistry  method,  whereas  ASM  apoptosis  by  TUNEL  method. Independent sample t-test and spearman test was used in statistical analysis with confident interval 95%. The  bronchioli  and  lungs  specimens  were  obtained  from  18  mice  (9  in  each  group).  Case  goup  had  significant +increase  in  the  amount of ASM apoptosis and expression of CD8   T cell lymphocyte  (p=0.000;  p=0.001). +There was also positif correlation between  ASM apoptosis and expression of CD8   T cell (r=0.37,  p=0.065). +We  conclude  that  increasing  ASM  apoptosis  has  a  relationship  with  increasing  CD8   T  cell+Keywords:  asthma,  mice,  ovalbumin,  ASM  apoptosis  and  CD8   T  cell
ANALISIS DAN PERANCANGAN PENGOLAHAN DATA ARSIP PADA KANTOR NOTARIS DAN PEJABAT PEMBUAT AKTA TANAH (PPAT) ISMET TAUFIK, S.H KOTA JAMBI Setiawati, Dessy; Marthiawati, Noneng; Ediansa, Oka
Jurnal Informatika, Sistem Informasi dan Kehutanan (FORSINTA) Vol. 3 No. 2 (2024): Jurnal Informatika, Sistem Informasi dan Kehutanan (Forsinta)
Publisher : LPPM Universitas Muhammadiyah Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53978/jfsa.v3i2.472

Abstract

Many companies, including the Notary Office and PPAT Ismet Taufik, S.H. in Jambi City, still rely on manual systems, leading to poorly organized archive data and inefficient data searches that hinder work processes. This research aims to analyze and design a web-based archival data processing system to improve data organization and search efficiency. Using the UML (Unified Modeling Language) methodology, this study incorporates use case diagrams, activity diagrams, and class diagrams. The system design follows a Prototype model visualized using the Canva application. The result is a design for a more effective and efficient archival data processing system tailored for the Notary Office and PPAT Ismet Taufik, S.H.
Co-Authors Ediansa, Oka HMS Chandra Kusuma Kusworini Handono Marthiawati, Noneng