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Implementation of teleHealth using SKEDit for protein diet education for diabetes patients Khoirul Rista Abidin; Eka Riana
Media Keperawatan Indonesia Vol 4, No 4 (2021)
Publisher : Universitas Muhammadiyah Semarang

A protein diet is an alternative to control hyperglycemia and hyperlipidemia conditions in diabetic patients. However, for the program to run optimally, the implementation of technology in the form of TeleHealth is needed to help educate patients on a regular and flexible basis. The purpose of this study was to analyze the effectiveness of implementing TeleHealth using the SKEDIt application for protein diet education in diabetic patients. Methods: This research is a quasi-experimental study, pre and post-test with a control group. The subjects involved were 20 diabetic patients, divided into 2 groups (intervention and control). Parameters analyzed were lipid profile and blood glucose levels. There was no difference in lipid profile and blood glucose levels between the intervention and control groups (p > 0.05). However, there was a difference between the pre and post-test on cholesterol parameters in the lipid profile examination of the control group: p=0.031 and LDL p=0.021 (p <0.05). Implementation of TeleHealth using SKEDit may be an effective recommendation to support health education methods but needs to be supported by good patient compliance.

Efektifitas Poster Edukasi Diet Tinggi Protein Melalui WhatsApp terhadap Kadar Glukosa Darah Pasien Diabetes Eka Riana; Khoirul Rista Abidin; Ismaulidia Nurvembrianti; Sofia Afritasari
Jurnal Ilmu Kesehatan Masyarakat Vol 12 No 05 (2023): Jurnal Ilmu Kesehatan Masyarakat
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikm.v12i05.2218

Penyakit diabetes merupakan penyakit gangguan metabolisme kronis yang menyebabkan kematian tertinggi di dunia. Ada berbagai tipe diabetes salah satunya diabetes tipe 2 yang termasuk ke dalam penyakit seumur hidup. Adapun faktor penyebab terjadinya DM diantaranya kebiasaan mengkonsumsi makanan tinggi lemak dan obesitas. Diet yang dapat dilakukan untuk mengatasi permasalahan ini diantaranya dengan diet tinggi protein. Tujuan dari studi ini adalah untuk melihat efektifitas Informasi yang di sampaikan melalui poster edukasi diet tinggi protein yang di kirim ke nomor WhatsApp pasien. Metode penelitian yang digunakan ialah kuasi eksperimen, pre dan post test dengan control group. Adapun populasi ialah pasien rawat jalan dan inap Klinik PKU Muhammadiyah Kitamura yang di diagnosis diabetes mellitus tipe 2 sebanyak 20 pasien. Efek diet tinggi protein terhadap kadar glukosa darah pasien diabetes menggunakan poster yang dibagikan melalui pesan singkat (WhatsApp) belum menjadi rekomendasi (nilai p = 0,97). Diperlukan tingkat kepatuhan pasien yang sangat tinggi terhadap edukasi yang diberikan agar hasil lebih optimal.

PENINGKATAN CITRA PROGRAM STUDI TEKNOLOGI LABORATORIUM MEDIK MELALUI WEBINAR PROFESI Puji Astuti; Khoirul Rista Abidin; Puspa Amalia; Fadli Sukandiarsyah; Zahro Mufida
Jurnal Inovasi dan Terapan Pengabdian Masyarakat Vol. 1 No. 1 (2021)
Publisher : Politeknik 'Aisyiyah Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35721/jitpemas.v1i1.13

Background: Medical Laboratory Technologist (ATLM) is one of the important types of health workers in Indonesia. However, it is less popular than other health professions such as doctor, nurse, and midwife. This low image causes student interest in pursuing education in the Medical Laboratory Technology study program to be relatively low. The webinar about ATLM’s profession for students is expected to improve the image of the TLM study program. Purpose: This community service aims to improve the image of the medical laboratory technology study program through profession webinars. Result: The results of this dedication show that profession webinars are quite popular for the public with up to 120 webinar participants, but this webinar cannot directly improve the image of the TLM study program, which is marked by the low number of students who become students in the TLM department at Politeknik Aisyiyah Pontianak (35%). Conclusion: Webinars are a promotional medium that is in great demand, but it has not been able to improve the image of the medical laboratory technology study program. Continuous efforts are needed to be able to improve the image of a study program or profession.

EDUKASI SECARA DARING TENTANG PEMANFAATAN MOODLE UNTUK GURU DAN DOSEN SELAMA PANDEMI COVID-19 Khoirul Rista Abidin; Puji Astuti; Zahro Mufida; Fadli Sukandiarsyah; Puspa Amalia
Jurnal Inovasi dan Terapan Pengabdian Masyarakat Vol. 1 No. 1 (2021)
Publisher : Politeknik 'Aisyiyah Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35721/jitpemas.v1i1.14

Background Online learning is the implementing learning and teaching process that is carried out without face to face directly or by means of applications via the internet. Moodle is one of the learning applications that can be included. Purpose : This study is aimed to analyze the effect of online education on educators, namely teachers and lecturers, regarding the use of Moodle as a resource for distance learning during the Covid-19 pandemic. Methods: Moodle educational activities were conducted online for 2 days by inviting all educators from Sabang to Merauke. At the end of the activity, participants were evaluated by asking to fill in quiz questions to determine their level of understanding about Moodle. Results Participants who took part in the Moodle training activity were 763 people, consisting of teachers and lecturers with an educational background of S1, S2 and S3. The results of the evaluation are as many as 85% of subjects get a score of> 50. Conclusion Moodle can be a recommendation application to support innovative distance learning.

WEBINAR NASIONAL TUBERKULOSIS PADA MASA PANDEMI COVID -19 DI LINGKUNGAN MASYARAKAT Khairul Bariyah; Khoirul Rista Abidin; Luluk Deka Fatmawati; Ainun Sa'adah
Jurnal Inovasi dan Terapan Pengabdian Masyarakat Vol. 1 No. 2 (2021)
Publisher : Politeknik 'Aisyiyah Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35721/jitpemas.v1i2.20

Tuberculosis is a direct infectious disease caused by Tuberculosis bacteria (Microbacterium Tuberculosis). The response to the Covid-19 pandemic requires adjustments to other health program services, including TB services that are run at health care facilities. Indonesia is the country with the most Covid-19 cases in Southeast Asia. Where people with Covid-19 and TB can show the same symptoms as cough, fever, and difficulty breathing. Both of these diseases attack mainly the lungs and both biological agents are transmitted through close contact or physical contact. Objective: to determine the relationship between science and tuberculosis prevention during the Covid-19 pandemic in the community. Methods: questionnaires on data collection techniques in quantitative research as community service and the role of health webinar participants in science and prevention of tuberculosis during the Covid-19 pandemic in the community. The media used is the website of the Pontianak Aisyiyah Polytechnic campus (Polita). This community service was carried out on February 4, 2021. Results: The number of participants who registered for the webinar was 1,498 people, where participants in the science category were in the very good category on tuberculosis and prevention 98.7% - 79.6%, good category on transmission with family and environment 65.2%-59.2%, and the lowest method of TB examination is 40.9%. Conclusion: This study involved webinar participants in knowledge and prevention of TB, the highest was 98.7% and the lowest was the method of TB examination, 40.9%, which was carried out in the laboratory. This National Health Webinar is a solution in handling knowledge and preventing Tuberculosis during the Covid-19 pandemic in Indonesian society.

Efektifitas Poster Edukasi Diet Tinggi Protein Melalui WhatsApp terhadap Kadar Glukosa Darah Pasien Diabetes Eka Riana; Khoirul Rista Abidin; Ismaulidia Nurvembrianti; Sofia Afritasari
Jurnal Ilmu Kesehatan Masyarakat Vol 12 No 05 (2023): Jurnal Ilmu Kesehatan Masyarakat
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikm.v12i05.2218

Penyakit diabetes merupakan penyakit gangguan metabolisme kronis yang menyebabkan kematian tertinggi di dunia. Ada berbagai tipe diabetes salah satunya diabetes tipe 2 yang termasuk ke dalam penyakit seumur hidup. Adapun faktor penyebab terjadinya DM diantaranya kebiasaan mengkonsumsi makanan tinggi lemak dan obesitas. Diet yang dapat dilakukan untuk mengatasi permasalahan ini diantaranya dengan diet tinggi protein. Tujuan dari studi ini adalah untuk melihat efektifitas Informasi yang di sampaikan melalui poster edukasi diet tinggi protein yang di kirim ke nomor WhatsApp pasien. Metode penelitian yang digunakan ialah kuasi eksperimen, pre dan post test dengan control group. Adapun populasi ialah pasien rawat jalan dan inap Klinik PKU Muhammadiyah Kitamura yang di diagnosis diabetes mellitus tipe 2 sebanyak 20 pasien. Efek diet tinggi protein terhadap kadar glukosa darah pasien diabetes menggunakan poster yang dibagikan melalui pesan singkat (WhatsApp) belum menjadi rekomendasi (nilai p = 0,97). Diperlukan tingkat kepatuhan pasien yang sangat tinggi terhadap edukasi yang diberikan agar hasil lebih optimal.

In Silico Approaches to Analyze a Potency of Mangostin Compounds as Inhibitors of Gardnerella vaginalis Arsella Nur; Khoirul Rista Abidin; Adelia Chintya Ningrum; Febrina Siregar; Suchi Suchi; M. Dzaki Al-Ghifari
Indonesian Journal of Herbal and Biomedical Research Vol. 1 No. 1 (2025)
Publisher : Bahiraliya Natura Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66982/ijhbr.v1i1.1

Background: Gardnerella vaginalis is the predominant pathogen in bacterial vaginosis (BV), known for its biofilm formation and increasing resistance to standard antibiotics such as metronidazole. Natural compounds such as xanthones from Garcinia mangostana, including α-, β-, and γ-mangostin, have shown antimicrobial properties and are promising as alternative therapeutic candidates. Aims: This study aimed to evaluate the potential of α-mangostin, β-mangostin, and γ-mangostin as inhibitors of G. vaginalis using in silico approaches, focusing on their interactions with the DAHP synthase enzyme. Methods: The study involved ligand preparation with energy minimization using Chem3D, receptor modeling of DAHP synthase through SWISS-MODEL, and validation using Ramachandran plot analysis. Molecular docking was conducted using HDock, while pharmacokinetic properties (ADME) were predicted using SwissADME and pkCSM. Molecular dynamic modeling was performed using the iMODS server, analyzing main-chain deformability, eigenvalues, elastic network, variance, and covariance. Results: γ-Mangostin showed the lowest docking score (–165.89) and highest confidence score (0.57), indicating strong affinity and interaction with active site residues such as Arg135A and Asp368A. ADME analysis revealed that all mangostin compounds had high gastrointestinal absorption with no Lipinski violations. Molecular dynamics simulations confirmed γ-mangostin’s ability to induce structural stability and coordinated residue motion in DAHP synthase, suggesting its favorable bioactive profile. Conclusions: γ-Mangostin is a promising natural inhibitor candidate against G. vaginalis through stable and specific interaction with DAHP synthase, supporting its potential for further in vitro and in vivo studies as a BV therapeutic agent.

Uji Aktivitas Ekstrak Etanol Kapulaga (Amomum compactum) sebagai Penghambat Pertumbuhan Candida albicans Marda Hamelya Putri; Khoirul Rista Abidin; Khairul Bariyah; Puspa Amalia
Indonesian Journal of Herbal and Biomedical Research Vol. 1 No. 1 (2025)
Publisher : Bahiraliya Natura Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66982/ijhbr.v1i1.2

This study aimed to evaluate the antifungal effectiveness of ethanol extract of cardamom against Candida albicans. The well diffusion method was used with extract concentrations of 5%, 10%, and 15%, alongside a positive control (ketoconazole). The inhibition zone was measured to assess antifungal activity. The 15% extract concentration produced an average inhibition zone of 16.56 ± 0.86 mm, categorized as moderate inhibition. These findings suggest that A. compactum possesses antifungal potential due to its bioactive compounds, such as flavonoids and tannins, which are known for their antimicrobial properties. The growing resistance of Candida albicans to synthetic antifungal agents highlights the importance of exploring natural alternatives. Hence, A. compactum extract demonstrates promising potential as a natural antifungal candidate that could be further developed for pharmaceutical or herbal formulations. The 15% ethanol extract of A. compactum exhibited measurable inhibitory activity against Candida albicans, with inhibition zones of 16.7 mm, 17.65 mm, 16.3 mm, and 15.6 mm across four replications. The mean inhibition zone was 16.56 mm with a standard deviation of 0.86 mm, indicating moderate antifungal strength. The variation among replicates was within the expected range for microbiological assays and may result from minor differences in extract diffusion or fungal growth conditions.

Activities Analysis of Encapsulated Mitragyna speciosa Extracts in High-Fat Diet-Induced Rats Model: In vivo and In silico Studies : Nanoparticles of M. speciosa to High-fat Diet Rats Khoirul Rista Abidin; Mas Rizky AA Syamsunarno; Aziiz Mardanarian Rosdianto; Kelana Kusuma Dharma; Ronny Lesmana; Nasrul Wathoni; Sriwidodo Sriwidodo
Indonesian Journal of Herbal and Biomedical Research Vol. 1 No. 1 (2025)
Publisher : Bahiraliya Natura Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66982/ijhbr.v1i1.3

Background: UCP-1 deficiency can be addressed through the activation of thermogenesis using various herbs, including Mitragyna speciosa (M. speciosa ). Purpose: This study aims to evaluate the efficacy of M. speciosa extracts, encapsulated in nanoparticles, in stimulating the activity of UCP-1 . Methods: The research utilized an in silico approach to test the docking of Mitragynine and epinephrine ligands against β1 and β3 adrenergic receptors. The nanoparticles were prepared using chitosan, alginate, and polyethylene glycol (PEG). An in vivo study was performed utilizing Wistar rats subjected to a high-fat diet (HFD) and assigned to six groups: Normal, HFD, HFD + MG50, HFD + Npm5, HFD + Npm10, and HFD + Npm20. The induction period for all groups was set at four weeks. Results: The docking tests yielded binding scores of -189.55 for Mitragynine against the β1 adrenergic receptor and -179.76 for the β3 receptor. The interactions between Mitragynine and the adrenergic receptors involved amino residues similar to those found in the native ligand epinephrine, specifically Asn1006A, Ser1007A, and Asn1022A for β1, and Asn332R for β3. Nanoparticles at doses of 5, 10, and 20 mg/kg BW demonstrated significant differences (p < 0.05) in body temperature and UCP-1 levels. Notably, the 10 and 20 mg/kg BW dosages did not lead to weight gain in the rats (p > 0.05). Conclusion: Mitragynine shows potential as an agonist for β1 and β3 adrenergic receptors. Furthermore, the nanoparticles at 5, 10, and 20 mg/kg BW were effective in stimulating UCP-1 activity and elevating body temperature in rats subjected to a high-fat diet.

Formulation and Characterization of Uncaria gambir (U. gambir) Extract Cream as an Anti-Psoriasis Candidate: In Silico and In Vitro Studies Khoirul Rista Abidin; Ariffialdi Nurhidayattulloh; Febrina Siregar; Abdurrafi Maududi Dermawan; Fath Dwisari; Oktaviria Oktaviria; Suchi Suchi; Melly Indriani; Firda Aulia Putri; Hernyati Prasetyaningsi; Shofia Shofia
Indonesian Journal of Chemical Research Vol 13 No 3 (2026): Edition for January 2026
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2026.13-kho

Background: Psoriasis is a chronic inflammatory skin disorder in which oxidative stress and COX-2–mediated pathways contribute to disease progression. Conventional topical therapies, particularly corticosteroids, are effective but associated with adverse effects and limited mechanistic targeting. Objective: This study investigated Uncaria gambir (U. gambir) extract as a natural anti-psoriasis candidate in a topical cream formulation through phytochemical, antioxidant, in silico, and physicochemical evaluations. Methods: The extract was screened for phenolic and flavonoid content and evaluated for DPPH radical scavenging activity (IC₅₀). Molecular docking of catechin against the COX-2 receptor was performed using quercetin as a reference. Cream formulations containing varying extract concentrations were assessed for pH, spreadability, and adhesiveness. Results: U. gambir extract exhibited very strong antioxidant activity (IC₅₀ = 6.84 ppm), falling within the range of highly active antioxidants, although less potent than vitamin C. Catechin showed stable COX-2 binding (−4.76 kcal/mol). The 4.5% cream formulation (F2) demonstrated optimal properties, with a skin-compatible pH (~7.5) and good spreadability (~5.5 cm). Conclusion: U. gambir extract shows promising potential as a natural topical agent targeting oxidative stress and inflammation in psoriasis, supporting further in vivo and clinical validation.

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