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T Sjafriati
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Veterinary

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Mareks Disease in Chicken: I. Aetiology, Pathogenesis and its Control Adjid, R M A; Damayanti, R; Hamid, H; Sjafriati, T; ., Darminto
Indonesian Bulletin of Animal and Veterinary Sciences Vol 12, No 2 (2002)
Publisher : Indonesian Animal Sciences Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.523 KB) | DOI: 10.14334/wartazoa.v12i2.768

Abstract

Marek’s disease (MD) is a neoplastic and neuropathic disease of poultry, especially chicken, caused by a highly contagious cell-associated herpesvirus. Marek’s disease is one of poultry diseases that is seriously concerned by poultry farmers. Before introduction of vaccine technology, the disease caused great economic loss in poultry industry, for example, in the United State the annual losses was estimated around $150 millions. Marek’s disease virus is relatively resistant to physical and chemical influence.  In  poultry  farms  the  virus  remains infectious  for  months  and  play  an  important  role  as  source of  infection. Pathogenesis of the disease is complex and influenced by factors. There are four phases of infection: early cytolytic infection, latent infection, second phase of cytolytic infection, and proliferative infection. Pathogenesis influenced by factors causes variety on clinical syndroms and incubation period of the disease in field condition. Successful disease control can be achieved, with vaccination as the main program, by selection of breed resistance and good management systems. The emergence of more virulent pathotypes of MD is a serious threat to the poultry industry, which requires development of more effective control strategies.   Key words. Marek, poultry, etiology, pathogenesis, control
Marek's Disease in Chicken: I. Aetiology, Pathogenesis and its Control R M A Adjid; R Damayanti; H Hamid; T Sjafriati; Darminto .
WARTAZOA, Indonesian Bulletin of Animal and Veterinary Sciences Vol 12, No 2 (2002)
Publisher : Indonesian Center for Animal Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.523 KB) | DOI: 10.14334/wartazoa.v12i2.768

Abstract

Marek’s disease (MD) is a neoplastic and neuropathic disease of poultry, especially chicken, caused by a highly contagious cell-associated herpesvirus. Marek’s disease is one of poultry diseases that is seriously concerned by poultry farmers. Before introduction of vaccine technology, the disease caused great economic loss in poultry industry, for example, in the United State the annual losses was estimated around $150 millions. Marek’s disease virus is relatively resistant to physical and chemical influence.  In  poultry  farms  the  virus  remains infectious  for  months  and  play  an  important  role  as  source of  infection. Pathogenesis of the disease is complex and influenced by factors. There are four phases of infection: early cytolytic infection, latent infection, second phase of cytolytic infection, and proliferative infection. Pathogenesis influenced by factors causes variety on clinical syndroms and incubation period of the disease in field condition. Successful disease control can be achieved, with vaccination as the main program, by selection of breed resistance and good management systems. The emergence of more virulent pathotypes of MD is a serious threat to the poultry industry, which requires development of more effective control strategies.   Key words. Marek, poultry, etiology, pathogenesis, control
Co-Authors Darminto . Darminto . H Hamid R Damayanti R M A Adjid