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All Journal WARTAZOA Indonesian Bulletin of Animal and Veterinary Sciences
R M A Adjid
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Veterinary

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Mareks Disease in Chicken: I. Aetiology, Pathogenesis and its Control Adjid, R M A; Damayanti, R; Hamid, H; Sjafriati, T; ., Darminto
Indonesian Bulletin of Animal and Veterinary Sciences Vol 12, No 2 (2002)
Publisher : Indonesian Animal Sciences Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.523 KB) | DOI: 10.14334/wartazoa.v12i2.768

Abstract

Marek’s disease (MD) is a neoplastic and neuropathic disease of poultry, especially chicken, caused by a highly contagious cell-associated herpesvirus. Marek’s disease is one of poultry diseases that is seriously concerned by poultry farmers. Before introduction of vaccine technology, the disease caused great economic loss in poultry industry, for example, in the United State the annual losses was estimated around $150 millions. Marek’s disease virus is relatively resistant to physical and chemical influence.  In  poultry  farms  the  virus  remains infectious  for  months  and  play  an  important  role  as  source of  infection. Pathogenesis of the disease is complex and influenced by factors. There are four phases of infection: early cytolytic infection, latent infection, second phase of cytolytic infection, and proliferative infection. Pathogenesis influenced by factors causes variety on clinical syndroms and incubation period of the disease in field condition. Successful disease control can be achieved, with vaccination as the main program, by selection of breed resistance and good management systems. The emergence of more virulent pathotypes of MD is a serious threat to the poultry industry, which requires development of more effective control strategies.   Key words. Marek, poultry, etiology, pathogenesis, control
Rabies in Indonesia and The Development of Its:Diagnostic Techniques Adjid, R M A; Sarosa, A; Syafriati, T; ., Yuningsih
Indonesian Bulletin of Animal and Veterinary Sciences Vol 15, No 4 (2005)
Publisher : Indonesian Animal Sciences Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (855.845 KB) | DOI: 10.14334/wartazoa.v15i4.816

Abstract

Rabies is a zoonotic disease which is crucial for public health, as it can infect human beings and causes death . Rabies has spread across the world including Indonesia . Control to erradicate rabies still faces many obstacles. Rabies research at Research Institute for Veterinary Science emphasizes on rabies erradication focussing on some aspects of diagnostic techniques. Studies on the spesimen preservation, the shipment to the laboratory and the collection of brain specimens by straw method as well as the use of cornea touch preparat as intra vitam specimens have been conducted. Rabies diagnostic techniques by NPLA or modified FAVN on multispot slides and their applications in the field have also been studied. This paper also describes the preparation of FITC conjugate. ELISA technique was developed for serological test but still need to be improved to reduce non specific reaction, while RREID was used for antigen detection. Rabies diagnostic was conducted by using RT-PCR but its application was very difficult to be done for intra vitam. Research on Croton tiglium and Pangium edule extracts as an alternative for the strychnine poison used for dog elimination in the field has also been conducted but further research is needed in the future. Key words: Rabies, zoonosis, research, diagnostic
Rabies in Indonesia and The Development of Its:Diagnostic Techniques R M A Adjid; A Sarosa; T Syafriati; Yuningsih .
WARTAZOA, Indonesian Bulletin of Animal and Veterinary Sciences Vol 15, No 4 (2005): DECEMBER 2005
Publisher : Indonesian Center for Animal Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (855.845 KB) | DOI: 10.14334/wartazoa.v15i4.816

Abstract

Rabies is a zoonotic disease which is crucial for public health, as it can infect human beings and causes death . Rabies has spread across the world including Indonesia . Control to erradicate rabies still faces many obstacles. Rabies research at Research Institute for Veterinary Science emphasizes on rabies erradication focussing on some aspects of diagnostic techniques. Studies on the spesimen preservation, the shipment to the laboratory and the collection of brain specimens by straw method as well as the use of cornea touch preparat as intra vitam specimens have been conducted. Rabies diagnostic techniques by NPLA or modified FAVN on multispot slides and their applications in the field have also been studied. This paper also describes the preparation of FITC conjugate. ELISA technique was developed for serological test but still need to be improved to reduce non specific reaction, while RREID was used for antigen detection. Rabies diagnostic was conducted by using RT-PCR but its application was very difficult to be done for intra vitam. Research on Croton tiglium and Pangium edule extracts as an alternative for the strychnine poison used for dog elimination in the field has also been conducted but further research is needed in the future. Key words: Rabies, zoonosis, research, diagnostic
Marek's Disease in Chicken: I. Aetiology, Pathogenesis and its Control R M A Adjid; R Damayanti; H Hamid; T Sjafriati; Darminto .
WARTAZOA, Indonesian Bulletin of Animal and Veterinary Sciences Vol 12, No 2 (2002)
Publisher : Indonesian Center for Animal Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.523 KB) | DOI: 10.14334/wartazoa.v12i2.768

Abstract

Marek’s disease (MD) is a neoplastic and neuropathic disease of poultry, especially chicken, caused by a highly contagious cell-associated herpesvirus. Marek’s disease is one of poultry diseases that is seriously concerned by poultry farmers. Before introduction of vaccine technology, the disease caused great economic loss in poultry industry, for example, in the United State the annual losses was estimated around $150 millions. Marek’s disease virus is relatively resistant to physical and chemical influence.  In  poultry  farms  the  virus  remains infectious  for  months  and  play  an  important  role  as  source of  infection. Pathogenesis of the disease is complex and influenced by factors. There are four phases of infection: early cytolytic infection, latent infection, second phase of cytolytic infection, and proliferative infection. Pathogenesis influenced by factors causes variety on clinical syndroms and incubation period of the disease in field condition. Successful disease control can be achieved, with vaccination as the main program, by selection of breed resistance and good management systems. The emergence of more virulent pathotypes of MD is a serious threat to the poultry industry, which requires development of more effective control strategies.   Key words. Marek, poultry, etiology, pathogenesis, control
Co-Authors A Sarosa Darminto . Darminto . H Hamid R Damayanti T Sjafriati T Syafriati Yuningsih .