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Duration and frequency of catheterization in central vein stenosis: A case control study Suhartono, Raden; Supit, Caroline
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

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Abstract

Introduction. Placement of the central vein catheterization (CVC) is a major risk factor for central vein stenosis (CVS). Repetitive endothelial exposures to the CVC results in inflammation, microthrombi formation, hyperplasia of the intima, fibrosis and thus development of CVS. The study aimed to find out the correlation between the duration and frequency of CVC in patients with CVS. Method. A matched case-control study was conducted in dr. Cipto Mangunkusumo General Hospital. Samples were taken from the medical record. Multivariate statistical comparisons were done using Chi-square tests. Results. Fifty–four out of 717 patients underwent CVC for hemodialysis had CVS. A total of 32 patients with CVS enrolled in the study with 128 non–CVS patients as a control. Duration of CVC >6 weeks does not increase the risk of CVS (p = 0.207), whilst the odds ratio of CVS on the frequency of CVC >2 times is 30 times compared to those underwent 2 times increased the risk of CVS. Longer duration of CVC for hemodialysis did not increase CVS rate.
Pengaruh Maturitas Sistem Pengendalian Intern Pemerintah (SPIP) Dan Kapabilitas Aparat Pengawasan Intern Pemerintah (APIP) Terhadap Indeks Persepsi Korupsi Indonesia Suhartono, Raden
MAKSI UNTAN Vol 6, No 2 (2021): JURNAL MAHASISWA MAGISTER AKUNTANSI
Publisher : FAKULTAS EKONOMI DAN BISNIS UNTAN

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Abstract

This  thesis  aims  to  determine  whether  the  maturity  of  the  implementation  of  the government   internal   control  system  (SPIP)  and  the  capability  of  the  provincial /district/city  government  internal  control  apparatus  (APIP)  in  Indonesia  affect  the  corruption  perception index  in  Indonesia. The sample used in this study were 508 districts  / cities   in   Indonesia    during    2017-2019.    This    research    was    conducted    with    a  quantitative  approach  processed  with  the  help  of  SPSS.  This  study  uses  quantitative  analysis  methods which include descriptive analysis, classical assumptions, simple linear  regression,  hypothesis testing t test, F test, and the coefficient of determination (R2). The results of this study indicate that the maturity SPIP and the capabilities APIP in provinces/  istricts/cities  in  Indonesia  have  an  influence  on  the  corruption  perception  index  in Indonesia
The Role of Catheter Directed Thrombolysis on Acute Limb Ischemia (an Evidence-Based Case Report) Ali Farhan Fathoni; Raden Suhartono
Jurnal llmu Bedah Indonesia Vol. 49 No. 1 (2021): Juni 2021
Publisher : Ikatan Ahli Bedah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46800/jibiikabi.v49i1.79

Abstract

Introduction. Acute limb ischemia can be managed both with surgery and thrombolysis, especially catheter-directed thrombolysis. The risk, benefit and indication of thrombolysis is already well known. However, as a first line therapy, it is unclear which intervention is more beneficial; the catheter directed thrombolysis or surgery. This report aims to elucidate which technique is more effective and safer. Method. This is an Evidence-Based Case Report based on a case of a geriatric, diabetic patient whom suffered acute limb ischemia. The report systematically search for meta-analysis, systematic review, randomized controlled trial and cohort studies from Cochrane central and PubMed for all adult patient suffering from acute limb ischemia whose are treated with catheter-directed thrombolysis or surgery as first-line intervention and comparing the outcome in terms of efficacy (clinical outcome such as patency and amputation-free rates) and safety (mortality and morbidity). Results. Subjects’ characteristics should be placed first to draw the demography. Put the study finding(s) here with no interpretation. For all adult patient regardless of their diabetic status and age there is no statistically significant difference for limb salvage, amputation, and mortality between two technique, however catheter directed thrombolysis showed reduced need for additional intervention whilst increasing risk of bleeding events. Conclusion. Neither techniques are more superior than the other but catheter-directed thrombolysis can be considered given that it reduce the need for further intervention, less invasive and even though it has risks for bleeding complication it is still lower compared to systemic thrombolysis. The selection of which technique can be up to clinician’s discretion in consideration of risk and benefit for each patient.
After A Year of Follow Up Non-Cirrhotic Portal Hypertension Patient with Partial Spleen Embolization (PSE) Management Akhmadu Muradi; Chyntia Olivia Maurine Jasirwan; Raden Suhartono; Patrianef Darwis; Dedy Pratama; Teguh Dwi Nugroho; Karina Zulkarnain
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 3 (2021): VOLUME 22, NUMBER 3, December 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2019.322 KB) | DOI: 10.24871/2232021249-253

Abstract

Non-cirrhotic portal hypertension (NCPH) is a heterogeneous group of liver disorders leading to portal hypertension. There are multiple approaches to managing portal hypertension' clinical complications to treat/prevent spontaneous hemorrhage by mitigating thrombocytopenia. Portal hypertension complications have been traditionally managed with serial endoscopic variceal ligation (EVL) or with invasive open surgical procedures such as orthotopic liver transplantation (OLT) or portosystemic shunting, splenectomy.6–9 There are several risks associated with splenectomies, such as hemorrhagic complications or intraoperative blood loss.5,6,14 Partial Spleen Embolization (PSE) ‎may overcome the limitations of splenectomy and provide patients with an alternative treatment. An eighteen-year-old male has a splenomegaly history since he was 12 years old and has recurring hematemesis and melena. After performing abdominal computed tomography, laboratory studies, and several endoscopies, the results indicated secondary hypersplenism due to non-cirrhotic portal hypertension. The patient had 13 endoscopies and 2 EVL in 5 years. Despite adequate treatment, the patients developed recurrent variceal bleeding and no improvement in blood function. The patient underwent PSE at Integrated Cardiovascular Center in Dr. Cipto Mangunkusumo, General Hospital, Jakarta, Indonesia. It was performed through the femoral access with a PVA (polyvinyl alcohol) embolus. The procedure went successful, and there was no major complication with the patient. Twenty days after the patient had an abdominal CT scan, it showed no abscess, and the spleen volume was reduced by 20%. Long-term results over a  year after the procedure are presented. PSE is a safe, effective, semi-invasive alternative to splenectomy in non-cirrhotic portal hypertension because it preserves functional spleen mass and avoids postprocedure accelerated liver disease or encephalopathy.
Surgical Shunting Versus Trans-Jugular Intrahepatic Portosystemic Shunt for Recurrent Variceal Bleeding in Portal Hypertension Due to Liver Cirrhosis: An Evidence-Based Case Report Magfira, Nadya; Nurrafiani, Arie Rozzaqi; Jasirwan, Chyntia Olivia Maurine; Suhartono, Raden
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 3 (2023): VOLUME 24, NUMBER 3, December, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2432023264

Abstract

Aim: This evidence-based case report aims to determine whether the surgical shunt is better than the trans-jugular intrahepatic portosystemic shunt (TIPS) to prevent re-bleeding in patients with portal hypertension due to liver cirrhosis.  Method: Literature searching was performed in 4 online databases, Cochrane, PubMed, Embase, and SCOPUS. Three meta-analyses were appraised critically.Results: Of all meta-analyses included, the internal validities were poor and only included a small number of trials. However, the results show that surgical shunt is better for preventing variceal re-bleeding with varied heterogeneities.Conclusion: Surgical shunts may have benefits over TIPS in preventing variceal re-bleeding. 
Navigating the intersection of COVID-19 and lower extremity acute limb ischemia: A retrospective cohort study of clinical characteristics and outcomes at Dr. Cipto Mangunkusumo Hospital Muradi, Akhmadu; Fachriza, Ihza; Pratama, Dedy; Suhartono, Raden; Harunarashid, Hanafiah
Narra J Vol. 5 No. 3 (2025): December 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i3.2557

Abstract

Acute limb ischemia (ALI), a critical condition threatening limb viability and patient survival, has demonstrated an increased incidence during the COVID-19 pandemic, primarily due to virus-associated thrombotic complications. The pandemic has also led to delays in the diagnosis and treatment of non-COVID conditions, including ALI. The aim of this study was to evaluate the clinical characteristics and outcomes of ALI patients treated at Dr. Cipto Mangunkusumo Hospital between 2018 and 2022, comparing outcomes before and during the COVID-19 pandemic. Patients were categorized into two cohorts: pre-pandemic (n=28) and pandemic (n=53), with March 2020 marking the onset of the pandemic period. Treatment outcomes—revascularization success, re-intervention, and mortality—were assessed using multivariate logistic regression. Among the 81 patients, 34.6% were treated before the pandemic and 65.4% during the pandemic. Revascularization success was significantly higher during the pandemic (relative risk (RR): 2.46; 95% confidence interval (CI): 1.16–5.24; p=0.013), whereas no significant differences were observed in re-intervention or mortality rates (both with p>0.05). A prior history of COVID-19 was not significantly associated with revascularization outcome (p=0.933). The use of fluoroscopic guidance was significantly associated with improved revascularization success (RR: 36.58; 95%CI: 6.54–204.6; p=0.001). Rutherford classification was a significant predictor of re-intervention success (p=0.022), while the presence of dyslipidemia and cardiovascular disease were independently associated with mortality (RR: 0.08–0.76, p=0.0o5, and RR: 2.24–25.18, p=0.001, respectively). In conclusion, fluoroscopy appears to enhance revascularization outcomes in the treatment of ALI. Comorbidities such cardiovascular disease, and COVID-19 history should be taken into account when managing patients with ALI.
Evaluation of the Influence of Risk Factors on the Time of Onset of Ulcers, Rest Pain, and New Gangrene Post-Angioplasty in Patients with Chronic Limb Threatening Ischemia (CLTI) at Dr. Cipto Mangunkusumo General Hospital Effendi, Haikal; Suhartono, Raden; Kekalih, Aria
Indonesian Journal of Multidisciplinary Science Vol. 4 No. 11 (2025): Indonesian Journal of Multidisciplinary Science
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/ijoms.v4i11.1178

Abstract

Chronic Limb Threatening Ischemia (CLTI) represents the end stage of peripheral arterial disease, characterized by rest pain, ulcers, and gangrene. This study aims to evaluate the influence of metabolic risk factors—namely diabetes mellitus (DM), chronic kidney disease (CKD), and hypertension—on the timing of new symptom onset. This study employed a retrospective observational design involving CLTI patients who underwent successful angioplasty at RSUPN Dr. Cipto Mangunkusumo. Clinical data and the onset time of symptoms were collected and analyzed using univariate, bivariate, and multivariate logistic regression analyses. The study revealed a high prevalence of diabetes mellitus (89.3%, with 56% uncontrolled), hypertension (77.3%, with 41.3% uncontrolled), and chronic kidney disease (32%). Post-angioplasty symptoms included gangrene (33.3%), rest pain (24%), combined rest pain and gangrene (24%), and ulcers (18.7%), with a mean onset time of 80 ± 105 days. Uncontrolled diabetes mellitus (p=0.001; mean 39.46 days), hypertension (p=0.006; mean 54.81 days), and chronic kidney disease (p=0.001; mean 29.58 days) were significantly associated with accelerated symptom onset. Multivariate regression analysis identified hypertension as the strongest predictor (p=0.021; B=59.234; ?=0.273), followed by DM (p=0.027; B=40.693; ?=0.249) and CKD (p=0.036; B=30.234; ?=0.226), collectively explaining 53.9% of the variation in onset time. Uncontrolled DM was associated with increased incidence of ulcers and gangrene; hypertension with combined rest pain and gangrene; while CKD was more frequently associated with rest pain. These findings highlight the importance of aggressive risk factor management and structured post-angioplasty monitoring to delay symptom onset and reduce complications.
Comparison of ABI, TBI, TOE Pressure, and Ankle Pressure Examinations in PAD Patients, Before and After Angioplasty with and without Type 2 DM at RSCM Rizki, Mohammad Nazril; Suhartono, Raden; Herqutanto , Herqutanto
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 8 (2025): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i8.4753

Abstract

Diabetes Mellitus (DM) exacerbates peripheral artery disease (PAD) and can affect the diagnostic accuracy of the ankle-brachial index (ABI) due to arterial calcification. Alternative examinations such as toe-brachial index (TBI), toe pressure (TP), and ankle pressure (AP) require evaluation to compare their effectiveness post-angioplasty in PAD patients with and without DM. This study aims to compare the changes in the values of these four parameters before and after angioplasty in both groups of patients. Method. This retrospective cohort study involved 78 PAD patients (39 with DM, 39 without DM) at Cipto Mangunkusumo Hospital. Hemodynamic parameters (ABI, TBI, AP, TP) were measured 24 hours before and after angioplasty. Bivariate analysis and linear regression are used to assess changes and their predictive factors. Post-angioplasty, all parameters showed significant improvement in both groups. However, the delta differences between groups were only significant in ABI and AP, not in TBI and TP. Preangioplasty parameter values were the main predictors of the magnitude of post-operative changes (p<0.001), while age had only a significant effect on delta TBI and TP. Conclusion. Angioplasty significantly improved ABI, TBI, TP, and AP values in PAD patients with and without type 2 DM. There was a significant difference between the delta parameters of ABI and AP in both groups after angioplasty. The value of the clinical parameters of preangioplasty had an effect on the delta value of each parameter, while age only affected the change in TBI and TP. The finding that TBI and TP did not show  significant delta differences  between the DM and non-DM groups implied that these two parameters were more robust and less affected by the condition of diabetes, making them worthy of consideration as a more reliable assessment tool, particularly in diabetic populations at risk of arterial calcification.
The Correlation of Smoking and Coffee Consumption with Diabetic Foot Ulcer Using Wifi Criteria at Cut Meutia General Hospital, Lhokseumawe Syafruddin, Syafruddin; Suhartono, Raden; Sanyoto, Dhanasari Vidiawati
Indonesian Journal of Multidisciplinary Science Vol. 4 No. 12 (2025): Indonesian Journal of Multidisciplinary Science
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/ijoms.v4i12.1187

Abstract

Diabetic Foot Ulcer (DFU) is a serious complication of diabetes mellitus. Risk factors such as smoking habits and coffee consumption have been associated with poor glucose control and vascular dysfunction; however, their relationship to the severity of DFU is not yet fully understood. The severity of DFU wounds can be assessed using the clinically validated WIFI system (Wound, Ischemia, and Foot Infection). This research aims to evaluate the association between smoking habits and coffee consumption with the severity of DFU based on the WIFI score in patients at RSUD Cut Meutia, Aceh. This was a cross-sectional study involving 188 DFU patients who met the inclusion criteria. Statistical analysis was performed using the Chi-square test of independence. Results show a significant association was found between moderate smoking and DFU severity (p=0.002). Coffee consumption was not significantly associated with the severity of DFU (p=0.468). In multivariate analysis, no significant effect of smoking or coffee consumption on WIFI scores was found when analyzed simultaneously (p>0.05). Moderate smoking is associated with increased DFU severity, especially when combined with light or moderate coffee consumption. Coffee consumption alone did not show a meaningful relationship. The multivariate analysis did not reveal a significant simultaneous effect of both variables, suggesting the potential influence of other confounding factors on DFU severity.