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All Journal Medical Journal of Indonesia Journal of Medical Physics and Biophysics
Djarwani Soeharso Soejoko
Department of Physics, Faculty of Mathematics and Natural Sciences, University of Indonesia
Medicine & Pharmacology Physics

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Virtual study to investigate the detectability of breast abnormalities on 2D mammography and digital breast tomosynthesis Kristina Tri Wigati; Hannah Manssens; Liesbeth Vancoillie; Cockmartin Lesley; Djarwani Soeharso Soejoko; Hilde Bosmans; Kristina Bliznakova
Journal of Medical Physics and Biophysics Vol 5, No 1 (2018)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1576.455 KB)

Abstract

This paper describes the use of virtual clinical trial software, as developed and improved in the frame of the Horizon2020 MaXIMA project, to study particular aspects of 2D mammography and digital breast tomosynthesis. A voxel-based breast phantom with inserted mathematical models of an irregular mass and two microcalcifications was created. Image acquisition was simulated by using XRAYImagingSimulator, while image reconstruction was accomplished with FDKR software. Series of images were created for different angular ranges with an identical total dose. Detectability of the abnormalities was investigated using visual assessment and quantitative measurements. The results agree with other studies in literature studying the same aspects and therefore confirm the value of the new framework for other future applications.
Bone growth evaluation in collagen-hydroxyapatite implant locations using digital radiography: an animal model Sari, Laela; Julia, Siti; Lubis, Lukmanda Evan; Sihono, Dwi Seno Kuncoro; Sari, Yessie Widya; Soejoko, Djarwani Soeharso
Medical Journal of Indonesia Vol. 32 No. 4 (2023): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.237051

Abstract

BACKGROUND Digital radiography has been used to evaluate the progress of bone growth with a collagen-hydroxyapatite implant in rabbit tibias. This study aimed to introduce digital radiography methods that provide comprehensive data availability for continuous information retrieval from the implant preparation to the cultivation period. METHODS 38 digital radiographs were divided into 3 treatment groups, namely a single defect without implant (control), single-implant, and three-implant. Radiographic acquisitions were performed at preparation time and post-implantation from 0 to 56 days. Observations were concentrated on the implantation site, followed by creating a lateral profile. The prediction of implantation growth was determined using relative bone density (RBD) percentage. RESULTS Based on the profile, the recovery process consisted of implant absorption and new bone tissue deposition. The absorption process was highly influenced by the defect size. In the control and single-implant groups, regardless of the different recovery processes, similar recovery results were observed 56 days post-implantation, with an RBD value of approximately 90%. Meanwhile, the three-implant group only had an RBD value of 62%. CONCLUSIONS Radiography can evaluate absorption and new bone growth during implantation in New Zealand white rabbits. Radiographs, which can be obtained at any time during cultivation, offered more information on the recovery implantation process than the other method that relies on data obtained after sacrificing the animals.
Co-Authors Cockmartin Lesley Hannah Manssens Hilde Bosmans Julia, Siti Kristina Bliznakova Kristina Tri Wigati laela Sari, laela Liesbeth Vancoillie Lubis, Lukmanda Evan Sihono, Dwi Seno Kuncoro Yessie Widya Sari